Results 161 to 170 of about 6,769,906 (346)
ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma
In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In
Daniel K. C. Lee +9 more
wiley +1 more source
ACUTE INFLAMMATION in the HEAD and EYES after WITNESSING ELECTRIC WELDING OPERATIONS: Its PREVENTION and TREATMENT [PDF]
H. Bendelack Hewetson
openalex +1 more source
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima +6 more
wiley +1 more source
Editorial: Novel and emerging therapies in heart failure
Grigorios Giamouzis +8 more
doaj +1 more source
2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure
P. Ponikowski +20 more
semanticscholar +1 more source
EFFECTS OF ACUTE ANOXIA ON THE CIRCULATION AND RESPIRATION IN PATIENTS WITH CHRONIC PULMONARY DISEASE STUDIED DURING THE “STEADY STATE” 1 [PDF]
A. P. Fishman +3 more
openalex +1 more source
Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides +13 more
wiley +1 more source

