Results 11 to 20 of about 190,176 (265)

A novel nomogram for adult primary perihilar cholangiocarcinoma and considerations concerning lymph node dissection

Frontiers in Surgery, 2023
ObjectiveTo construct a reliable nomogram available online to predict the postoperative survival of patients with perihilar cholangiocarcinoma.MethodsData from 1808 patients diagnosed with perihilar cholangiocarcinoma between 2004 and 2015 were extracted
Qi Zhang, Qi Zhang, Zehan Liu, Zehan Liu, Shuangqing Liu, Ming Wang, Xinye Li, Jing Xun, Jing Xun, Xiangyu Wang, Qin Yang, Ximo Wang, Dapeng Zhang, Dapeng Zhang   +13 more
doaj   +1 more source

The Crucial Role of PPARγ-Egr-1-Pro-Inflammatory Mediators Axis in IgG Immune Complex-Induced Acute Lung Injury

Frontiers in Immunology, 2021
BackgroundThe ligand-activated transcription factor peroxisome proliferator-activated receptor (PPAR) γ plays crucial roles in diverse biological processes including cellular metabolism, differentiation, development, and immune response.
Chunguang Yan, Chunguang Yan, Chunguang Yan, Jing Chen, Yue Ding, Zetian Zhou, Bingyu Li, Chunmin Deng, Dong Yuan, Qi Zhang, Ximo Wang   +10 more
doaj   +1 more source

IgG immune complex-induced acute lung injury is ameliorated by cAMP via down-regulation of C/EBP- and AP-1-mediated transcriptions

Journal of Inflammation, 2023
Background Acute lung injury (ALI) and its more severe form, acute respiratory distress syndrome (ARDS) are life threatening pulmonary diseases, and we are now lack of effective therapeutic methods. Inflammatory responses are essential for initiating ALI/
Chunguang Yan, Jing Chen, Huifang Tang, Chunmin Deng, Qi Zhang, Ximo Wang   +5 more
doaj   +1 more source

The effect of ursodeoxycholic acid on the relative expression of the lipid metabolism genes in mouse cholesterol gallstone models

Lipids in Health and Disease, 2020
Background Many studies indicate that gallstone formation has genetic components. The abnormal expression of lipid-related genes could be the basis for particular forms of cholesterol gallstone disease.
Ning Fan, Ke Meng, Yuqing Zhang, Yong Hu, Donghua Li, Qiaoying Gao, Jianhua Wang, Yanning Li, Shangwei Wu, Yunfeng Cui   +9 more
doaj   +1 more source

CD44 is a potential immunotherapeutic target and affects macrophage infiltration leading to poor prognosis

Scientific Reports, 2023
CD44 plays a key role in the communication of CSCs with the microenvironment and the regulation of stem cell properties. UALCAN was used to analyze the expression of CD44 in bladder cancer (BLCA) and normal tissue.
Shuangqing Liu, Zehan Liu, Aichen Shang, Jing Xun, Zongjing Lv, Siying Zhou, Cui Liu, Qi Zhang, Yuming Yang   +8 more
doaj   +1 more source

Analysis of risk factors for intra-cystic hemorrhage in microwave ablation of partially cystic thyroid nodules

Frontiers in Endocrinology, 2023
ObjectiveThe aim of this study is to identify risk factors of intra-cystic hemorrhage in microwave ablation of mixed solid and cystic microwave ablation s, and to design a preoperative nomogram to predict the risk value of intraoperative bleeding with ...
Yao Fu, Yuhui Huang, Yongtai Liu, Yu Song   +3 more
doaj   +1 more source

Sodium selenite inhibits proliferation and metastasis through ROS‐mediated NF‐κB signaling in renal cell carcinoma

BMC Cancer, 2022
Background Sodium selenite (SSE) has been reported to exert anti-tumor effects in several cancer cells. However, the underlying mechanisms in renal cancer are yet to be elucidated.
Xiao Liu, Meng Jiang, Chenggang Pang, Jianning Wang, Lijuan Hu   +4 more
doaj   +1 more source

Cinnamomi Ramulus inhibits the growth of colon cancer cells via Akt/ERK signaling pathways

Chinese Medicine, 2022
Background Colon cancer (CC) ranks the second highest mortality rate among malignant tumors worldwide, and the current mainstream treatment regimens are not very effective.
Boyu Pan, Yafei Xia, Zilu Gao, Gang Zhao, Liangjiao Wang, Senbiao Fang, Liren Liu, Shu Yan   +7 more
doaj   +1 more source

Optimizing the Method of Cell Separation from Bile of Patients with Cholangiocarcinoma for Flow Cytometry

Gastroenterology Research and Practice, 2019
Analysis of the change of the cells in bile is an evolving research field in biliary pathophysiology and has potential value in diagnosis and therapy. However, laboratory studies of cell in bile across the world are scarce.
Yafei Xia, Yuan Gao, Botao Wang, Hui Zhang, Qi Zhang   +4 more
doaj   +1 more source

Survival for Children Diagnosed With Wilms Tumour (2012–2022) Registered in the UK and Ireland Improving Population Outcomes for Renal Tumours of Childhood (IMPORT) Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background The Improving Population Outcomes for Renal Tumours of childhood (IMPORT) is a prospective clinical observational study capturing detailed demographic and outcome data on children and young people diagnosed with renal tumours in the United Kingdom and the Republic of Ireland.
Naomi Ssenyonga, Angela Lopez‐Cortes, Reem Al‐Saadi, Suzanne Tugnait, Kristina Dzhuma, Catriona Duncan, Gordan Vujanic, Tanzina Chowdhury, Claudia Allemani, Michel P. Coleman, Kathy Pritchard‐Jones, the Children's Cancer and Leukaemia Group (CCLG) Renal Tumour Special Interest Group, Hugh Bishop, Anthony McCarthy, Pamela Kearns, Helen Rees, Amos Burke, Meriel Jenney, Jane Pears, Hamish Wallace, Milind Ronghe, Tanzina Chowdhury, Susan Picton, Emma Ross, Lisa Howell, Bernadette Brennan, Gail Halliday, Richard Grundy, Shaun Wilson, Sucheta Vaidya, Daniel Yeomanson, Jessica Bate, Vesna Pavasovic, Jessica Bate, Sabine Irtan, Jesper Brok, Minou Oostveen, Kristina Dzhuma, Mark Weeks, Richard Williams, Mark Powis, Max Pachl, Bruce Okoye, Naima Smeulders, Gordan Vujanic, Oystein Olsen, Tom Watson, Susan Shelmerdine, Dan Saunders, Angela Lopez-Cortes, Taryn Treger, Tom Jackson, Suzanne Tugnait, Lisa Howell, Tanzina Chowdhury, Sam Behjati, Angela Polanco   +56 more
wiley   +1 more source