Results 121 to 130 of about 15,063,784 (383)

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Tandem Mass Tag (TMT) Proteomic Analysis of Saliva in Horses with Acute Abdominal Disease [PDF]

, 2021
Alberto Muñoz-Prieto, Damián Escribano, María Dolores Contreras-Aguilar, Anita Horvatić, Nicolas Guillemin, Stine Jacobsen, J. M. Castro Cerón, Vladimir Mrljak   +7 more
openalex   +1 more source

EPI Update, August 10, 2012 [PDF]

, 2012
Weekly newsletter for Center For Acute Disease Epidemiology of Iowa Department of Public ...

core  

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Knowledge of prevention and treatment of infectious diarrhea among parents of children under five with diarrhea in Anhui province: an outpatient-clinic-based questionnaire survey

Zhongguo gonggong weisheng
ObjectiveTo assess the status and determinants of knowledge of prevention and treatment of infectious diarrhea among parents of children aged ≤5 years with diarrhea to provide evidence for the development of targeted health intervention strategies ...
Yuanfang SUN, Yongkang XIAO, Lei GONG, Hongyuan WEI, Wanwan MA, Shuo FENG, Qiang ZHANG, Linlin LI, Qile WU, Jiabing WU   +9 more
doaj   +1 more source

A new reportable disease is born: Taiwan Centers for Disease Control's response to emerging Zika virus infection

Journal of the Formosan Medical Association, 2016
Zika virus infection, usually a mild disease transmitted through the bite of Aedes mosquitos, has been reported to be possibly associated with microcephaly and neurologic complications.
Angela Song-En Huang, Pei-Yun Shu, Chin-Hui Yang   +2 more
doaj   +1 more source

EPI Update, October 9, 2009 [PDF]

, 2009
Weekly newsletter for Center For Acute Disease Epidemiology of Iowa Department of Public ...

core  

Climate change and the kidney [PDF]

, 2019
The worldwide increase in temperature has resulted in a marked increase in heat waves (heat extremes) that carries a markedly increased risk for morbidity and mortality.
Butler-Dawson, Jaime, Diaz, Henry F., Garcia, Gabriela, Hernando, Ana Andres, Johnson, Richard J., Lanaspa, Miguel A., Lemery, Jay, Newman, Lee S., Rodriguez-Iturbe, Bernardo, Roncal-Jimenez, Carlos A., Sato, Yuka, Sánchez-Lozada, Laura G., Tolan, Dean R.   +12 more
core   +1 more source

Biomarkers of Acute and Chronic Kidney Disease.

Annual Review of Physiology, 2019
The current unidimensional paradigm of kidney disease detection is incompatible with the complexity and heterogeneity of renal pathology. The diagnosis of kidney disease has largely focused on glomerular filtration, while assessment of kidney tubular ...
William R Zhang, C. Parikh
semanticscholar   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source