Results 121 to 130 of about 3,932,966 (340)

Blinatumomab vs historic standard‐of‐care treatment for minimal residual disease in adults with B‐cell precursor acute lymphoblastic leukaemia [PDF]

, 2019
Nicola Gökbuget, Hervé Dombret, Sebastian Giebel, Monika Brüggemann, Michael Doubek, Robin Foà, Dieter Hoelzer, Christopher Kim, Giovanni Martinelli, Е. Н. Паровичникова, Josep‐María Ribera, Marieke Schoonen, Catherine Tuglus, Gerhard Zugmaier, Renato Bassan   +14 more
openalex   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

The latency time of SARS-CoV- 2 Delta variant in infection- and vaccine-naive individuals from Vietnam

BMC Infectious Diseases
Background The latency time (from infection to infectiousness) guides the choice of measures required to control an infectious disease. Estimates of the SARS-CoV- 2 latency time are sparse due to lack of appropriate and representative data.
Vera H. Arntzen, Manh Nguyen Duc, Marta Fiocco, Lan Truong Thi Thanh, Tam Nguyen Hoai Thao, Buu Mai Thanh, Tu-Anh Nguyen, Nhat Le Thanh Hoang, Marc Choisy, Lam Phung Khanh, Nga Le Hong, Ronald B. Geskus   +11 more
doaj   +1 more source

Digital health and acute kidney injury: consensus report of the 27th Acute Disease Quality Initiative workgroup. [PDF]

Nat Rev Nephrol, 2023
Kashani KB, Awdishu L, Bagshaw SM, Barreto EF, Claure-Del Granado R, Evans BJ, Forni LG, Ghosh E, Goldstein SL, Kane-Gill SL, Koola J, Koyner JL, Liu M, Murugan R, Nadkarni GN, Neyra JA, Ninan J, Ostermann M, Pannu N, Rashidi P, Ronco C, Rosner MH, Selby NM, Shickel B, Singh K, Soranno DE, Sutherland SM, Bihorac A, Mehta RL.   +28 more
europepmc   +1 more source

Review of Chagas Disease and Treatment Obstacles to Eradication [PDF]

, 2019
The World Health Organization and the Center for Disease Control reports Chagas disease, or American trypanosomiasis, as a major neglected tropical disease prevalent in 21 endemic Latin American countries.
Sherman, Emily
core   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Acute disease induced cognitive dysfunction in older patients - an unrecognized syndrome. [PDF]

BMC Geriatr, 2022
Wirth R, Klimek CN, Lueg G, Pourhassan M, Danielzik LM, Krüger C, Trampisch US.   +6 more
europepmc   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Antiviral activity of pimecrolimus against dengue virus type 2 infection in vitro and in vivo

Scientific Reports
Dengue virus (DENV) infection is a public health concern in several countries and is associated with severe diseases, such as dengue hemorrhagic fever and dengue shock syndrome.
Seong-Ryeol Kim, Jung-Min Lee, Hae Ji Kang, Jungsang Ryou, Sang-Mu Shim   +4 more
doaj   +1 more source

Acute hemiplegia associated with cat-scratch disease [PDF]

, 2004
Jaime Luís Lopes Rocha, L.N. Pellegrino, Leonardo V. Riella, Luzilma Terezinha Flenik Martins   +3 more
openalex   +1 more source