Results 161 to 170 of about 3,932,966 (340)

Downregulation of the cysE/cysK genes of Clostridioides difficile induced by cysteine revealed the response of bacteria to iron homeostasis

BMC Microbiology
Background Cysteine can affect the expression level of Clostridioides difficile toxins. CysE and cysK are the key genes involved in de novo cysteine synthesis in C. difficile.
Wenpeng Gu, Feng Liao, Lulu Bai, Wenzhu Zhang, Senquan Jia, Jianwen Yin, Yongming Zhou, Xiaoqing Fu, Yuan Wu   +8 more
doaj   +1 more source

Association between depression and three key COVID-19-related outcomes: The SHARE study

Human Vaccines & Immunotherapeutics
This study investigated the potential associations between preexisting depression and COVID-19 vaccination, SARS-CoV-2 infection risk, and long COVID among middle-aged and older Europeans, based on the Survey of Health, Ageing and Retirement in Europe ...
Yumeng Gao, Chunxiao Duan, Tongtong Miao, Qian Shen, Jia Yu, Suwen Shen, Yujun Chen, Yuan Shen, Kaixin Zhang   +8 more
doaj   +1 more source

Acute Abdominal Disease [PDF]

BMJ, 1950
openaire   +2 more sources

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Distinguishing Incubation and Acute Disease Stages of Mild-to-Moderate COVID-19. [PDF]

Viruses, 2022
Müller M, Volzke J, Subin B, Schmidt CJ, Geerdes-Fenge H, Reisinger EC, Müller-Hilke B.   +6 more
europepmc   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Comparison of post-COVID symptoms in patients with different severity profiles of the acute disease visited at a rehabilitation unit. [PDF]

PLoS One, 2022
Perrot JC, Segura M, Beranuy M, Gich I, Nadal MJ, Pintor A, Terra J, Ramirez E, Paz LD, Bascuñana H, Plaza V, Güell-Rous MR.   +11 more
europepmc   +1 more source

In‐Hospital Outcomes of Dual Loading Antiplatelet Therapy in Patients 75 Years and Older With Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention: Findings From the CCC‐ACS (Improving Care for Cardiovascular Disease in China‐Acute Coronary Syndrome) Project

, 2018
Guanqi Zhao, Mengge Zhou, Changsheng Ma, Yong Huo, Sidney C. Smith, Gregg C. Fonarow, Junbo Ge, Yaling Han, Jing Liu, Yongchen Hao, Jun Liu, Xiao Wang, Kathryn A. Taubert, Louise Morgan, Dong Zhao, Shaoping Nie, the CCC‐ACS Investigators   +16 more
openalex   +1 more source

Insights from early mathematical models of 2019-nCoV acute respiratory disease (COVID-19) dynamics [PDF]

, 2020
Jomar F. Rabajante
openalex   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source