Results 71 to 80 of about 14,159,590 (434)

Coeliac crisis with severe hypokalaemia in an adult [PDF]

, 2012
Coeliac crisis is a rare life-threatening presentation of coeliac disease, in which acute dramatic metabolic derangements are present. It is observed mainly in children less than two years of age. In adults, coeliac disease usually has an indolent course
Magro, Rosalie, Pullicino, Edgar
core  

Ablation of LRP6 in alpha‐smooth muscle actin‐expressing cells abrogates lung inflammation and fibrosis upon bleomycin‐induced lung injury

FEBS Letters, EarlyView.
Low‐density lipoprotein receptor‐related protein 6 (LRP6) is a key receptor for the Wnt antagonist Dickkopf1 (DKK1). DKK1 protein expression is induced in a bleomycin (BLM)‐induced lung injury model. We show that DKK1 induces proinflammatory and profibrotic genes in lung fibroblasts.
Eun‐Ah Sung, Mikhail G. Dozmorov, SuJeong Song, Theingi Aung, Min Hee Park, Patricia J. Sime, Wook‐Jin Chae   +6 more
wiley   +1 more source

Histone demethylase KDM6B inhibits breast cancer metastasis by regulating Wnt/β‐catenin signaling

FEBS Open Bio, 2021
Tumor metastasis remains a major challenge for patients with breast cancer. Aberrant epigenetic factor lysine‐specific demethylase 6B (KDM6B) has been associated with tumor progression.
Jing Xun, Ruifang Gao, Botao Wang, Yifan Li, Yuan Ma, Jun Guan, Qi Zhang   +6 more
doaj   +1 more source

New onset acute symptomatic seizure and risk factors in coronavirus disease 2019: A retrospective multicenter study

Epilepsia, 2020
Our aim was to clarify the incidence and risk of acute symptomatic seizures in people with coronavirus disease 2019 (COVID‐19). This multicenter retrospective study enrolled people with COVID‐19 from January 18 to February 18, 2020 at 42 government ...
Lu Lu, Weixi Xiong, Dan Liu, Jing Liu, Dan Yang, Nian Li, J. Mu, Jian Guo, Wei-min Li, Gang Wang, Hui Gao, Yingying Zhang, Mintao Lin, Lei Chen, Sisi Shen, Hesheng Zhang, Josemir W Sander, Jianfei Luo, Shengli Chen, Dong Zhou   +19 more
semanticscholar   +1 more source

Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells

FEBS Letters, EarlyView.
Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga, Kazuki Harada, Takuya Yamauchi, Tetsuya Kitaguchi, Masami Yokota Hirai, Mitsuharu Matsumoto, Takashi Tsuboi   +6 more
wiley   +1 more source

Spatial and Temporal Analysis of Severe Fever with Thrombocytopenia Syndrome in Anhui Province from 2011 to 2023

Journal of Epidemiology and Global Health
Objective To analyze the spatial autocorrelation and spatiotemporal clustering characteristics of severe fever with thrombocytopenia syndrome(SFTS) in Anhui Province from 2011 to 2023.
Xiu-Jie Chu, Dan-Dan Song, Na Chu, Jia-Bing Wu, Xiaomin Wu, Xiu-Zhi Chen, Ming Li, Qing Li, Qingqing Chen, Yong Sun, Lei Gong   +10 more
doaj   +1 more source

Epidemiological characteristics and influencing factors of hand, foot, and mouth disease outbreaks in Jiangsu province, 2010 – 2022: a register data analysis

Zhongguo gonggong weisheng
ObjectiveTo analyze epidemiological characteristics and determinants of hand, foot, and mouth disease (HFMD) outbreaks in Jiangsu province over the period of 2010 to 2022 for developing local HFMD prevention and control measures.
Mingyang LI, Xiaoqing CHENG, Ye WEI, Huan FAN, Xuefeng ZHANG, Changjun BAO, Qingxiang SHANG, Hong JI   +7 more
doaj   +1 more source

The International Registry of Acute Aortic Dissection (IRAD): new insights into an old disease.

Journal of the American Medical Association (JAMA), 2000
CONTEXT Acute aortic dissection is a life-threatening medical emergency associated with high rates of morbidity and mortality. Data are limited regarding the effect of recent imaging and therapeutic advances on patient care and outcomes in this setting.
Peter G. Hagan, Christoph A Nienaber, E. Isselbacher, D. Bruckman, Dean J. Karavite, P. Russman, A. Evangelista, R. Fattori, Toru Suzuki, Jae K. Oh, Andrew G Moore, Joseph F. Malouf, L. Pape, Charlene Gaca, Rn, U. Sechtem, Suzanne Lenferink, Hans J. Deutsch, H. Diedrichs, Jose Marcos y Robles, A. Llovet, D. Gilon, Sugata Das, William F. Armstrong, G. M. Deeb, Kim A. Eagle   +25 more
semanticscholar   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

FEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Isobavachalcone Activates Antitumor Immunity on Orthotopic Pancreatic Cancer Model: A Screening and Validation

Frontiers in Pharmacology, 2022
Pancreatic cancer is accompanied by poor prognosis and accounts for a significant number of deaths every year. Since Psoralea corylifolia L. (PCL) possesses a broad spectrum of bioactivities, it is commonly used in traditional Chinese medicine. The study
Xuanming Liu, Hongbo Zhang, Jianlin Cao, Yuzhen Zhuo, Jiahui Jin, Qiaoying Gao, Xiangfei Yuan, Lei Yang, Dihua Li, Yan Wang, Yan Wang   +10 more
doaj   +1 more source