Results 71 to 80 of about 3,639,746 (361)

Principles of appropriate antibiotic use for treatment of uncomplicated acute bronchitis: background. [PDF]

, 2001
The following principles of appropriate antibiotic use for adults with acute bronchitis apply to immunocompetent adults without complicating comorbid conditions, such as chronic lung or heart disease.
Bartlett, JG, Besser, RE, Centers for Disease Control and Prevention, Cooper, RJ, Gonzales, R, Hickner, JM, Hoffman, JR, Sande, MA   +7 more
core   +2 more sources

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

A case report of human infection with avian influenza H10N3 with a complex respiratory disease history

BMC Infectious Diseases
Background On March 16th 2024, the first case of Human infection with avian influenza H10N3 since the end of the global COVID-19 Pandemic was reported in Kunming, China.
Zhenxi Zhao, Siyi Luo, Yudong Gao, Min Dai, Jun Yan, Ying Yang, Hongwei Li, Yan Zhang, Zhipeng Mao   +8 more
doaj   +1 more source

Genomic Analyses Uncover Evolutionary Features of Influenza A/H3N2 Viruses in Yunnan Province, China, from 2017 to 2022

Viruses
Influenza A viruses evolve at a high rate of nucleotide substitution, thereby requiring continuous monitoring to determine the efficacy of vaccines and antiviral drugs.
Meiling Zhang, Jienan Zhou, Ruize Ni, Xiaonan Zhao, Yaoyao Chen, Yanhong Sun, Zhaosheng Liu, Xiaoyu Han, Chunrui Luo, Xiaoqing Fu, Yong Shao   +10 more
doaj   +1 more source

EPI Update, May 5, 2006 [PDF]

, 2006
Weekly newsletter for Center For Acute Disease Epidemiology of Iowa Department of Public ...

core  

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

EPI Update, May 18, 2010 [PDF]

, 2010
Weekly newsletter for Center For Acute Disease Epidemiology of Iowa Department of Public ...

core  

Gene Therapy for Acute Diseases

Molecular Therapy, 2001
The use of gene transfer systems to study cell function makes it apparent that overexpression of a transgene can restore or improve the function of a protein and positively influence cell function in a predetermined manner for purposes of counterbalancing cellular pathophysiology.
Phillip Factor, Phillip Factor
openaire   +3 more sources

The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1

FEBS Letters, EarlyView.
MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson, Robert Gustafsson Westergren, Ingrid Almlöf, Ann‐Sofie Jemth, Martin Scobie, Ulrika Warpman Berglund, Thomas Helleday, Pål Stenmark   +7 more
wiley   +1 more source

A new reportable disease is born: Taiwan Centers for Disease Control's response to emerging Zika virus infection

Journal of the Formosan Medical Association, 2016
Zika virus infection, usually a mild disease transmitted through the bite of Aedes mosquitos, has been reported to be possibly associated with microcephaly and neurologic complications.
Angela Song-En Huang, Pei-Yun Shu, Chin-Hui Yang   +2 more
doaj   +1 more source