Results 41 to 50 of about 292,830 (293)

Pharmacologically blocking p53-dependent apoptosis protects intestinal stem cells and mice from radiation. [PDF]

, 2015
Exposure to high levels of ionizing radiation (IR) leads to debilitating and dose-limiting gastrointestinal (GI) toxicity. Using three-dimensional mouse crypt culture, we demonstrated that p53 target PUMA mediates radiation-induced apoptosis via a cell ...
Cramer, Julie M, Dunn, James CY, Epperly, Michael, Greenberger, Joel, Judge, Colleen, Lagasse, Eric, Leibowitz, Brian J, Li, Linheng, Martin, Martin G, Stelzner, Matthias G, Wang, Fengchao, Wang, Xinwei, Wei, Liang, Yu, Jian, Zhang, Lin   +14 more
core   +2 more sources

Management of hyperkalemia in the acutely ill patient. [PDF]

, 2019
PURPOSE:To review the mechanisms of action, expected efficacy and side effects of strategies to control hyperkalemia in acutely ill patients. METHODS:We searched MEDLINE and EMBASE for relevant papers published in English between Jan 1, 1938, and July 1,
Dépret, François, Legrand, Matthieu, Liu, Kathleen D, Peacock, W Frank, Rafique, Zubaid, Rossignol, Patrick   +5 more
core   +3 more sources

Combining Acute Kidney Injury with Gastrointestinal Pathology: A Clue to Acute Oxalate Nephropathy

Case Reports in Nephrology, 2018
Acute oxalate nephropathy (AON) is an increasingly recognized cause of acute kidney injury (AKI). Herein, we present two cases of biopsy-proven acute oxalate nephropathy in patients with gastrointestinal malabsorption, coincidentally both stemming from cholangiocarcinoma.
Benjamin Fox, Nishkarsh Saxena, Leah Schuppener, Laura Maursetter   +3 more
openaire   +4 more sources

The effect of melatonin on bacterial translocation following ischemia/reperfusion injury in a rat model of superior mesenteric artery occlusion [PDF]

, 2015
Background: Acute mesenteric ischemia is a life-threatening vascular emergency resulting in tissue destruction due to ischemia-reperfusion injury. Melatonin, the primary hormone of the pineal gland, is a powerful scavenger of reactive oxygen species (ROS)
Aydin, B., Aydin, C., Berber, I., Birsen, O., Cevahir, N., Gumrukcu, G., Yenisey, C., Özban, Murat.   +7 more
core   +2 more sources

Investigating the Protective Effects of Atorvastatin against Radiotherapy-Induced Gastrointestinal Toxicity in Abdominal and Pelvic Cancers: A Randomized, Double-Blind, Placebo-Controlled Trial [PDF]

Middle East Journal of Cancer
Background: Radiotherapy (RT) for pelvic cancers often causes gastrointestinal toxicity. While statins show promise in reducing radiation-induced injury through anti-inflammatory properties, their impact on acute toxicity remains unclear. The aim of this
Dr.Nadia Najafi Zade, Neda Mohammadi, Simin Hemati   +2 more
doaj   +1 more source

Clinical features of alcoholic hepatitis in latinos and caucasians: A single center experience. [PDF]

, 2017
AimTo study differences of presentation, management, and prognosis of alcoholic hepatitis in Latinos compared to Caucasians.MethodsWe retrospectively screened 876 charts of Caucasian and Latino patients who were evaluated at University of California ...
Durbin-Johnson, Blythe, Halsted, Charles H, Medici, Valentina, Pinon-Gutierrez, Rogelio   +3 more
core   +1 more source

Albumin concentrations are primarily determined by the body cell mass and the systemic inflammatory response in cancer patients with weight loss [PDF]

, 2001
The association between hypoalbuminemia and poor prognosis in patients with cancer is well recognized. However, the factors that contribute to the fall in albumin concentrations are not well understood.
Colin S. McArdle, Donald C. McMillan, Fearon KCH, Hazel R. Scott, Kotler DP, McMillan DC, McMillan DC, Micozzi MS, O'Gorman P, Patricia O'Gorman, Preston T, Schneider SM, Tom Preston, Walter S. Watson, Watson WS   +14 more
core   +1 more source

Acute gastrointestinal injury in the intensive care unit: diagnosis, severity assessment, and general approaches to correction

Вестник анестезиологии и реаниматологии
Introduction. Acute gastrointestinal injury is a polymorphic syndrome with many causes.The objective was to consider modern aspects of diagnosis and assessment of severity of acute gastrointestinal injury.Materials and methods.
M. M. Sokolova, T. N. Semenkova, I. S. Zabaldin, V. V. Kuzkov, M. Yu. Kirov   +4 more
doaj   +1 more source

Transactivation of EGFR by LPS induces COX-2 expression in enterocytes [PDF]

, 2012
Necrotizing enterocolitis (NEC) is the leading cause of gastrointestinal morbidity and mortality in preterm infants. NEC is characterized by an exaggerated inflammatory response to bacterial flora leading to bowel necrosis.
A Grishin, AA Fanaroff, AA Maynard, Anatoly Grishin, AO Fagbemi, AV Grishin, B Dvorak, B Lugo, BB Warner, BJ Stoll, BK Reuter, CE Shin, CL Leaphart, Claus Schneider, CP Sodhi, D Hsu, D. Brent Polk, DH Chung, Henri Ford, JA Clark, Jeffrey Upperman, JL Koff, Jörn-Hendrik Weitkamp, M Fukata, M Fukata, M Petrosyan, MD Halpern, Michael J. Rosen, Michael Kallen, Nathalie Signoret, Noemi Tejera, O Morteau, P Chailler, PJ Miettinen, Poojitha Matta, PW Lin, RR Nair, S Cetin, SC Fitzgibbons, SC Gribar, SC Gribar, SO Guthrie, Steven J. McElroy, Stuart Hobbs, T Jilling, T Yamaoka   +45 more
core   +6 more sources

Colitis Associated With Sevelamer Carbonate: A Case Report

Annals of Internal Medicine: Clinical Cases, 2023
Sevelamer carbonate is an anion-exchange, nonabsorbable resin that is commonly used to treat hyperphosphatemia in patients with advanced chronic kidney disease and end-stage renal disease.
Prajwol Pant, David LaBel, Nora Hernandez Garcilazo, Shailendra Sharma, Sumughda Rayamajhi   +4 more
doaj   +1 more source