Results 61 to 70 of about 292,830 (293)

The Effects Of Acute Kidney Injury On The Outcomes Of Patients With Gastrointestinal Bleeding

Journal of Rawalpindi Medical College
Objective: To determine the clinical outcomes of patients with acute kidney injury in patients with upper gastrointestinal bleeding (UGIB), as it is a very frequently encountered condition with high morbidity and treatment costs.
Mahvesh Mahmud, Khurram Baqai, Ashok Kumar   +2 more
doaj   +1 more source

Acute Kidney Injury Associated With Semaglutide

Kidney Medicine, 2021
Case reports of acute kidney injury in patients taking the glucagon-like peptide 1 (GLP-1) receptor agonists exenatide and liraglutide have been reported.
David J. Leehey, Mohamed A. Rahman, Ewa Borys, Maria M. Picken, Christina E. Clise   +4 more
doaj   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

A review of the immunomodulating components of maternal breast milk and protection against necrotizing enterocolitis [PDF]

, 2019
Breast milk contains immunomodulating components that are beneficial to newborns during maturation of their immune system. Human breast milk composition is influenced by an infant\u27s gestational and chronological age, lactation stage, and the mother ...
Fiorentino, Jinquan, Lila S. Nolan, Misty Good, Moe-Byrne, Olivia B. Parks   +5 more
core   +2 more sources

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Acute Kidney Injury and Acute Renal Failure in Coronaviral Infection

Acta Medica Bulgarica, 2022
In December 2019 a newly described single-stranded coronavirus, later named SARS-CoV-2, started its expansion around the world and subsequently caused a global pandemic, affecting the lives of millions of people worldwide.
Nikolova M., Angelova I., Kotseva V., Kostadinova A., Genov D., Vutova C., Koleva N., Todorov J., Chupetlovska K., Penkov M., Ananiev J., Milenova V., Kundurdzhiev A.   +12 more
doaj   +1 more source

Transfusion-related acute lung injury in ICU patients admitted with gastrointestinal bleeding [PDF]

Intensive Care Medicine, 2010
Transfusion of blood components is common in patients admitted to the intensive care unit (ICU) for gastrointestinal (GI) bleeding, yet the incidence and risk factors for development of transfusion-related acute lung injury (TRALI) in these patients are unknown.Patients admitted to a medical ICU for GI bleeding (n = 225) were analyzed for patient- and ...
Alexander B, Benson, Gregory L, Austin, Mary, Berg, Kim K, McFann, Sila, Thomas, Gina, Ramirez, Hugo, Rosen, Christopher C, Silliman, Marc, Moss   +8 more
openaire   +2 more sources

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Structural analysis and treatment of acute liver injury of polysaccharides from the Radix Actinidiae Chinensis

Frontiers in Pharmacology
ObjectiveTo investigate the therapeutic effects of the PRAC on acute liver injury and its potential as an ingredient in drugs and nutraceuticals.MethodsMicrowave-assisted extraction technology combined with Box-Behnken model combined with the three kinds
Zhongpeng Ding, Qianyi Ying, Jing Lei, Jing Lei, Ningchen Zhang, Yu Xia, Yilin Du, Beihua Xu, Senlin Shi   +8 more
doaj   +1 more source

Hospital Readmission After Traumatic Brain Injury Hospitalization in Community‐Dwelling Older Adults

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the risk of hospital readmission after an index hospitalization for TBI in older adults. Methods Using data from the Atherosclerosis Risk in Communities (ARIC) study, we used propensity score matching of individuals with an index TBI‐related hospitalization to individuals with (1) non‐TBI hospitalizations (primary analysis)
Rachel Thomas, Connor A. Law, Joan A. Casey, Thomas Mosley, Rebecca F. Gottesman, Ramon Diaz‐Arrastia, Holly Elser, Andrea L. C. Schneider   +7 more
wiley   +1 more source