Results 71 to 80 of about 8,348,024 (289)

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

Ruxolitinib in refractory acute and chronic graft-versus-host disease: a multicenter survey study [PDF]

, 2020
Graft-versus-host disease is the main cause of morbidity and mortality after allogeneic hematopoietic stem cell transplantation. First-line treatment is based on the use of high doses of corticosteroids.
Sánchez Ortega, Isabel, Grupo Español de Trasplante Hematopoyético (GETH), Parody, Rocío   +2 more
core   +3 more sources

Lower gastrointestinal endoscopic findings in patients with acute gastrointestinal graft-versus-host disease or infectious colitis.

, 2018
Lower gastrointestinal endoscopic findings in patients with acute gastrointestinal graft-versus-host disease or infectious colitis.
Gota Sudo (5570936), Daisuke Hirayama (4396837), Tomoya Iida (4732995), Toshiyuki Kubo (5570939), Masanori Nojima (52788), Hiroo Yamano (5570942), Kentaro Yamashita (796584), Hiroshi Nakase (783451), Sae Ohwada (5570933)   +8 more
core   +1 more source

Self‐Assembling Copolymers Encapsulating Single Endothelial Cells Induce Endogenous ECM Deposition and Vascular Regeneration

Advanced Materials, EarlyView.
This study presents the first demonstration of stable sub‐50‐micron single‐cell GPM vesicles fabricated through the intrinsic self‐assembly of an amphiphilic copolymer. Hierarchical assembly of cell containing GPM vesicles into microspheres enable tunable, sustained cell delivery with immune protection.
Viola B. Morris, Sangho Lee, Kalp Soni, Simon He, Matthew Huang, Dandan Chen, Dae Hoon Lee, Kyung Hee Kim, Seonggeon Cho, Laura Pencea, Divit Jain, Young‐Sup Yoon   +11 more
wiley   +1 more source

Improved graft-versus-host disease-free, relapse-free survival associated with bone marrow as the stem cell source in adults

Haematologica, 2016
We previously reported that bone marrow grafts from matched sibling donors resulted in best graft-versus-host disease-free, relapse-free survival at 1-year post allogeneic hematopoietic cell transplantation.
Rohtesh S. Mehta, Regis Peffault de Latour, Todd E DeFor, Marie Robin, Aleksandr Lazaryan, Aliénor Xhaard, Nelli Bejanyan, Flore Sicre de Fontbrune, Mukta Arora, Claudio G. Brunstein, Bruce R. Blazar, Daniel J. Weisdorf, Margaret L. MacMillan, Gerard Socie, Shernan G. Holtan   +14 more
doaj   +1 more source

Radiative Thermal Management for Extreme Environments: Mechanisms and Design Strategies

Advanced Materials, EarlyView.
In this review, we discuss the fundamental mechanisms of radiative cooling and solar heating, material and structural design strategies, hybrid approaches integrating additional heat transfer pathways, and durability‐oriented designs addressing environmental stresses.
Hyung Rae Kim, Haeseong Kim, Joo Hwan Ko, Gil Ju Lee, Dae‐Hyeong Kim, Young Min Song   +5 more
wiley   +1 more source

Prediction, diagnosis and treatment of experimental graft-versus-host disease : an investigation of genomic, molecular and cellular factors in graft-versus-host disease and mesenchymal stromal cell therapy in a rat model of allogeneic stem cell transplantation [PDF]

, 2011
Patients who suffer from leukemia or lymphoma can be cured by the transplantation of bone marrow stem cells from a volunteer donor (allogeneic hematopoietic cell transplantation).
Zinöcker, Severin
core   +1 more source

Intelligent Micro/Nanorobots for Targeted Interventional Therapy: From Bench to Clinic

Advanced Robotics Research, EarlyView.
Zirui Zhang et al. reviewed the application and challenges of mobile nanomachines in interventional therapy. By converting exogenous energy, including chemical, magnetic, optical, and ultrasonic sources, into mechanical forces, micro/nanorobots (MNRs) enable precise actuation at unprecedented scales. Evolving far beyond traditional drug delivery, these
Zirui Zhang, Yu Dong, Yongsheng Du, Rui Gao, Lin Zhang, Fei Tong   +5 more
wiley   +1 more source

A prospective randomized trial comparing cyclosporine/methotrexate and tacrolimus/sirolimus as graft-versus-host disease prophylaxis after allogeneic hematopoietic stem cell transplantation

Haematologica, 2016
Improvement of graft-versus-host disease prophylaxis remains an important goal in allogeneic hematopoietic stem cell transplantation. Based on reports of possibly preferential properties of sirolimus, we compared the standard regimen of cyclosporine and ...
Johan Törlén, Olle Ringdén, Karin Garming-Legert, Per Ljungman, Jacek Winiarski, Kari Remes, Maija Itälä-Remes, Mats Remberger, Jonas Mattsson   +8 more
doaj   +1 more source

Oral chronic graft-versus-host disease: analysis of dendritic cells subpopulations [PDF]

Anais Brasileiros de Dermatologia, 2014
The graft-versus-host disease is the major cause of morbidity and mortality in patients who have undergone hematopoietic stem cell transplantation. Aiming at contributing to the understanding of the role of myeloid and plasmacytoid dendritic cells, and ...
Clara Marino Espricigo Botari, Adauto José Ferreira Nunes, Mair Pedro de Souza, Érica Sinara Lenharo Orti-Raduan, Ana Gabriela Salvio   +4 more
doaj   +2 more sources