Results 181 to 190 of about 677,866 (413)

Outcomes following Sonothrombolysis in Severe Acute Ischemic Stroke: Subgroup Analysis of the CLOTBUST Trial

open access: green, 2014
Kristian Barlinn   +10 more
openalex   +1 more source

Brd4 BD1 Domain Antagonism of MS436 Preserves Blood‐Brain Barrier Integrity via Rnf43/β‐Catenin Signaling Pathway

open access: yesAdvanced Science, EarlyView.
MS436 competitively binds to the BD1 domain of Brd4, thereby suppressing Brd4 induced degradation of tight junction proteins via the Rnf43‐Fzd4‐β‐catenin signaling pathway. Consequently, this attenuation of degradation reduces blood‐brain barrier leakage, leading to an improved overall prognosis after stroke.
Chenxiao Li   +10 more
wiley   +1 more source

Neuroprotective Nanoplatform Integrating Antioxidant MXene Nanozymes and Ferroptosis Inhibitors for Targeted Therapy of Cerebral Ischemia‐Reperfusion Injury

open access: yesAdvanced Science, EarlyView.
Cerebral ischemia‐reperfusion injury (CIRI) is a key pathological process limiting the efficacy of stroke therapy. This study has developed an innovative, multifunctional, brain‐targeted nanoplatform (RFP) containing MXene nanoenzymes and ferroptosis inhibitors.
Lu Wang   +9 more
wiley   +1 more source

Barthel Index Score and Total Serum Cholesterol Levels Correlation as Prognostic Tool for Acute Ischemic Stroke

open access: yesJLUMHS
OBJECTIVE: To find a correlation between total serum cholesterol (TSC) in acute ischemic stroke and their prognosis is assessed employing the Barthel Index (BI) score.
Zulfiqar Ali   +5 more
doaj   +1 more source

Acute ischemic stroke after enjoying Top of Europe [PDF]

open access: gold, 2021
Marina P. Krasteva   +2 more
openalex   +1 more source

Disrupting CSPG‐Driven Microglia–Astrocyte Crosstalk Enables Scar‐Free Repair in Spinal Cord Injury

open access: yesAdvanced Science, EarlyView.
This study identifies CSPGs as key drivers of glial scar maturation after spinal cord injury by reprogramming microglial metabolism and inducing astrocyte fibrosis. To address this, a reactive oxygen species‐responsive, reactive astrocyte‐targeted ChABC gene delivery system is designed to locally degrade CSPGs, precisely disrupt maladaptive glial ...
Yufei Zheng   +10 more
wiley   +1 more source

Neuronal plasma biomarkers in acute ischemic stroke [PDF]

open access: hybrid
Julia K. Gundersen   +10 more
openalex   +1 more source

EFFECTIVENESS OF EARLY REHABILITATION IN PATIENTS WITH ACUTE ISCHEMIC STROKE IN NEUROLOGY UNIT

open access: diamond, 2020
Оксана Іванівна Коленко   +2 more
openalex   +2 more sources

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