Results 191 to 200 of about 677,866 (413)

Crossing the Blood–Brain Barrier with Molecularly Imprinted Polymeric Nanocarriers: An Emerging Frontier in Brain Disease Therapy

Advanced Science, EarlyView.
Molecularly imprinted polymeric nanocarriers (nanoMIPs) offer robust, antibody‐mimetic platforms to overcome the blood‐brain barrier. The article surveys nanoMIP design and ligand‐directed surface engineering that harness receptor‐mediated transcytosis, and highlights therapeutic and diagnostic applications in neurodegeneration, brain tumors and ...
Ranjit De, Shuliang Shi, Kyong‐Tai Kim
wiley   +1 more source

Leucine‐Dependent SLC7A5–PGAM5 Interaction Promotes Advanced Atherosclerosis Through Hindering Mitochondrial Function of Macrophages

Advanced Science, EarlyView.
Higher plasma leucine is associated with increased risk of new‐onset myocardial infarction. Leucine deprivation alleviates advanced atherosclerosis in mice. Tumor‐induced leucine deprivation reprograms macrophage metabolism and increases CD5Lhi macrophages in mouse plaques. Mechanistically, leucine deficiency reduced SLC7A5‐PGAM5 binding in macrophages,
Shan Zhong, Xueyu Wang, Qingsong Li, Siqi Wang, Bin Sun, Wenjun Ni, Gengyu Zhou, Fan Wang, Xianwei Xie, Cheng Jin, Gang Xu, Peng Zhao, Xiang Peng, Feiyuan Han, Xiangwen Xi, Yidan Wang, Juan Xu, Yue Wang, Xia Gu, Shuo Li, Jian Zhang, Shuijie Li, Jinwei Tian   +22 more
wiley   +1 more source

Review for "High fibrinogen-to-albumin ratio is associated with hemorrhagic transformation in acute ischemic stroke patients"

, 2020
Yohei Tateishi
openalex   +1 more source

Advanced Therapeutic Approach Based on LDHs–Mimetic Oxidoreductase

Advanced Science, EarlyView.
Overview of Sructure, Multienzyme‐mimicking Activity and Advanced Therapeutic Approach Based on LDHs–Mimetic Oxidoreductase. Abstract Redox dysregulation is recognized as a key driver in the pathophysiology of numerous refractory diseases, contributing significantly to the progression and poor prognosis.
Kai Song, Yu Wei, Peng Jia, Shan He, Qian Wang, Manman Xu, Hongzhi Liu, Pengtao Bao, Shanyue Guan, Xiaozhong Qu   +9 more
wiley   +1 more source

Serum heme oxygenase‐1 level predicts clinical outcome after acute ischemic stroke [PDF]

Huan Wang, Ting Cui, Yaqi Chen, Mingxi Chen, Shihong Zhang, Xinyi Leng, Deren Wang   +6 more
openalex   +1 more source

Image processing-based mTICI grading after endovascular treatment for acute ischemic stroke [PDF]

, 2021
Muhannad Sabieleish, Maximilian Thormann, J. Metzler, Axel Boese, Michael Friebe, Anastasios Mpotsaris, Daniel Behme   +6 more
openalex   +1 more source

2018 Guidelines for the Early Management of Patients With Acute Ischemic Stroke.

Stroke, 2018
K. Furie, M. Jayaraman
semanticscholar   +1 more source

Cortical Microvascular Pulsatility in the Aging Mouse Brain and the Confounding Effects of Anesthesia

Advanced Science, EarlyView.
Multi‐modal optical imaging reveals microvascular pulsatility in the brain cortex of awake and anaesthetized mice. Awake hemodynamics in male mice are found to be remarkably stable until late life, with flow pulsatility being significantly higher than in females, despite similar average perfusion.
Mia Viuf Skøtt, Elizaveta Melnikova, Eugenio Gutiérrez, Vladimir Matchkov, Leif Østergaard, Dmitry D Postnov   +5 more
wiley   +1 more source

Effect of smoking status on clinical outcomes after reperfusion therapy for acute ischemic stroke [PDF]

F. Irie, Ryu Matsuo, Satomi Mezuki, Yoshinobu Wakisaka, Masahiro Kamouchi, Takanari Kitazono, Tetsuro Ago, Takao Ishitsuka, Setsuro Ibayashi, Kenji Kusuda, Kenichiro Fujii, T Nagao, Yasushi Okada, Masahiro Yasaka, Hiroaki Ooboshi, Takanari Kitazono, Katsumi Irie, Tsuyoshi Omae, Ḱazunori Toyoda, Hiroshi Nakane, Masahiro Kamouchi, Hiroshi Sugimori, Shuji Arakawa, Kenji Fukuda, Tetsuro Ago, Jiro Kitayama, Shigeru Fujimoto, Shoji Arihiro, Junya Kuroda, Yoshinobu Wakisaka, Yoshihisa Fukushima, Ryu Matsuo, F. Irie, Kuniyuki Nakamura, Takuya Kiyohara   +34 more
openalex   +1 more source

Recommendations on Angiographic Revascularization Grading Standards for Acute Ischemic Stroke: A Consensus Statement

Stroke, 2013
O. Zaidat, A. Yoo, P. Khatri, T. Tomsick, R. von Kummer, J. Saver, M. Marks, S. Prabhakaran, D. Kallmes, Brian-Fred M. Fitzsimmons, J. Mocco, J. Wardlaw, S. Barnwell, T. Jovin, I. Linfante, A. Siddiqui, M. Alexander, J. Hirsch, M. Wintermark, G. Albers, H. Woo, D. Heck, M. Lev, R. Aviv, W. Hacke, S. Warach, J. Broderick, C. Derdeyn, A. Furlan, R. Nogueira, D. Yavagal, M. Goyal, A. Demchuk, M. Bendszus, D. Liebeskind   +34 more
semanticscholar   +1 more source