Results 221 to 230 of about 377,245 (300)

Connecting the dots: A narrative review of the relationship between heart failure and cognitive impairment

ESC Heart Failure, Volume 12, Issue 2, Page 1119-1131, April 2025.
Abstract Large clinical data underscore that heart failure is independently associated to an increased risk of negative cognitive outcome and dementia. Emerging evidence suggests that cerebral hypoperfusion, stemming from reduced cardiac output and vascular pathology, may contribute to the largely overlapping vascular dementia and Alzheimer's disease ...
Mauro Massussi, Maria Giulia Bellicini, Marianna Adamo, Andrea Pilotto, Marco Metra, Alessandro Padovani, Riccardo Proietti   +6 more
wiley   +1 more source

Current state and advancements of imaging in acute ischemic stroke: a practical review. [PDF]

Neurol Sci
Al-Salahat A, Pirahanchi Y, Dhasakeerthi T, Nayar D, Almasri S, Verma K, Thatikala A, Alkhaldi M, Ebrahimzadeh SA, Shahsavari N, Godasi R, Kapoor N, Sharma R.   +12 more
europepmc   +1 more source

Development and validation of a deep survival model to predict time to seizure from routine electroencephalography

Epilepsia, EarlyView.
Abstract Objective This study was undertaken to develop and validate a deep survival model (EEGSurvNet) that analyzes routine electroencephalography (EEG) to predict individual seizure risk over time, comparing its performance to traditional clinical predictors such as interictal epileptiform discharges (IEDs).
Émile Lemoine, An Qi Xu, Mezen Jemel, Frédéric Lesage, Dang K. Nguyen, Elie Bou Assi   +5 more
wiley   +1 more source

Predictive performance of machine learning models in acute ischemic stroke: a systematic review and meta-analysis. [PDF]

Front Neurol
Khanum U, Guddattu V, Paneyala S, Srinivasan A, Nagaraju C.   +4 more
europepmc   +1 more source

Evolution of the European Medicines Agency clinical guidelines for epilepsy drug development between 2010 and 2025: A comparative analysis by the ILAE Task Force on Regulatory Affairs

Epilepsia, EarlyView.
Abstract Objective The latest European Medicines Agency (EMA) guideline on the clinical investigation of medicines to treat epileptic disorders was adopted by the EMA Committee for Medicinal Products for Human Use in 2025. We compared this guideline with the previous version (2010), highlighting areas where significant revisions were introduced ...
Stéphane Auvin, Alexis Arzimanoglou, Jacqueline French, Kelly G. Knupp, Lieven Lagae, Eugen Trinka, Dennis Dlugos, Emilio Perucca   +7 more
wiley   +1 more source

Areal differences in the utilization of endovascular therapy for acute ischemic stroke. [PDF]

Eur J Public Health
Junttola U, Hietanen S, Lahtinen S, Isokangas JM, Raatiniemi L, Kaakinen T, Vakkala M, Liisanantti J.   +7 more
europepmc   +1 more source

Long‐term safety of early discontinuation of antiseizure medication after resolution of acute provoked neonatal seizures

Epilepsia, EarlyView.
Abstract Objective To assess long‐term safety of antiseizure medication (ASM) discontinuation after resolution of acute provoked neonatal seizures and prior to hospital discharge. Methods Prospective, observational, comparative effectiveness cohort study of neonates with acute provoked seizures born from July 2015 to March 2018, and followed until ...
Hannah C. Glass, Adam L. Numis, Janet S. Soul, Courtney J. Wusthoff, Monica E. Lemmon, Catherine J. Chu, Shavonne L. Massey, Cameron Thomas, Tayyba Anwar, Madison M. Berl, Jennifer G. Larson, Julie Sturza, Dana Annis, Elizabeth E. Rogers, Linda S. Franck, Charles E. McCulloch, Renée A. Shellhaas   +16 more
wiley   +1 more source

Poststroke epilepsy is associated with vascular cognitive disorder in young stroke patients: The ODYSSEY study

Epilepsia, EarlyView.
Abstract Objective Cognitive disorder is common after stroke at a young age, especially in patients with poststroke epilepsy (PSE). Whether the causative mechanism is direct (due to epilepsy‐related network alterations) or indirect (due to effect‐modifiers such as stroke severity) is not fully understood.
Frederik J. Reitsma, Esmée Verburgt, Mijntje M. I. Schellekens, Nina A. Hilkens, Jamie I. Verhoeven, Mayte E. van Alebeek, Paul J. A. M. Brouwers, Renate M. Arntz, Gert W. van Dijk, Rob A. R. Gons, Inge W. M. van Uden, Tom den Heijer, Julia H. van Tuijl, Karlijn F. de Laat, Anouk van Norden, Sarah E. Vermeer, Marian S. G. van Zagten, Marieke J. H. Wermer, Paul J. Nederkoorn, Frank G. van Rooij, Ido R. van den Wijngaard, Paul L. M. de Kort, Roy P. C. Kessels, Anil M. Tuladhar, Robert J. van Oostenbrugge, Frank‐Erik de Leeuw, Rob P. W. Rouhl   +26 more
wiley   +1 more source

Acute Ischemic Stroke in Non-Arteritic Anterior Ischemic Optic Neuropathy. [PDF]

Diagnostics (Basel)
Wenzel V, Danyel LA, Meidinger S, Siebert E, Knoche T, Pietrock C.   +5 more
europepmc   +1 more source

Neonatal seizures: Advances in diagnosis and management

Epilepsia Open, EarlyView.
Abstract The International League Against Epilepsy (ILAE) created the ILAE Neonatal Task Force that classified neonatal seizures, defined neonatal epilepsy syndromes, and specified treatment guidelines. These frameworks, in addition to improved access to genetic testing and other recent advances, have revolutionized the diagnosis and management of ...
Elissa G. Yozawitz, Ronit M. Pressler, Eli M. Mizrahi   +2 more
wiley   +1 more source