Results 281 to 290 of about 677,866 (413)

Quantitative Model‐Informed Dose Selection for a Milvexian Phase III Study in Patients With Atrial Fibrillation

Clinical Pharmacology &Therapeutics, EarlyView.
Milvexian, an activated factor XI inhibitor, is being evaluated in the LIBREXIA phase III program for the prevention of thrombotic events, including in patients with atrial fibrillation (LIBREXIA AF). To guide the selection of a phase III dose regimen for LIBREXIA AF, two main approaches were used: (1) population pharmacokinetics and exposure–response ...
Wangda Zhou, Emily Bozenhardt, Gregory E. Alexander, Matthew L. Zierhut, Samira Merali, Antoinette Ajavon‐Hartmann, Peter Zannikos, Hyunmoon Back, EunYoung Suh, Navin Goyal, Mahesh N. Samtani, Alexei N. Plotnikov, Chandni Valiathan   +12 more
wiley   +1 more source

Efficacy of Human Urinary Kallidinogenase in Real-world Patients With Acute Ischemic Stroke: A Matched Comparison. [PDF]

Neurologist
Zhang Y, Luo X, Song X, Li J, Liu Y, Wang L, Tan G.   +6 more
europepmc   +1 more source

Clinical study of colorViz fusion image vascular grading based on multi-phase CTA reconstruction in acute ischemic stroke [PDF]

Qi Wang, Wang Qiang, Yingjie Xu, Xue Li, Daobin Zhou, Xiao-gang Sun, Bo Feng   +6 more
openalex   +1 more source

Real‐World Edoxaban Concentrations in Older Patients Receiving Reduced‐Dose Regimens

Clinical Pharmacology &Therapeutics, EarlyView.
Real‐world edoxaban concentrations in older patients receiving reduced‐dose regimens. Low trough concentrations (< 12 ng/mL) were associated with an increased risk of thromboembolism. Among patients meeting the ELDERCARE‐AF criteria, low drug levels were more frequent with the 15 mg regimen than with the 30 mg regimen.
Sung‐Chun Tang, Shin‐Yi Lin, Chih‐Hao Chen, Yen‐Bin Liu, Li‐Ting Ho, Ching‐Hua Kuo, Yu‐Fong Peng, Chih‐Fen Huang, Jiann‐Shing Jeng   +8 more
wiley   +1 more source

Predictive value of motor-evoked potentials for upper limb functional outcomes in acute ischemic stroke. [PDF]

Ann Med
Yen CC, Chen HH, Li YH, Lin CH.
europepmc   +1 more source

Safety of IV thrombolysis in acute ischemic stroke related to Chagas disease

, 2013
Pedro Cougo, Bruno Lopes dos Santos, Francisco Antunes Dias, Millene Rodrigues Camilo, Frederico Fernandes Aléssio-Alves, Clara Barreira, Taiza E. G. Santos-Pontelli, Daniel Giansante Abud, João Pereira Leite, Octávio Marques Pontes‐Neto   +9 more
openalex   +1 more source

Sensitivity of Diffusion- and Perfusion-Weighted Imaging for Diagnosing Acute Ischemic Stroke Is 97.5%

Stroke, 2015
C. Simonsen, M. Madsen, M. L. Schmitz, I. Mikkelsen, M. Fisher, G. Andersen   +5 more
semanticscholar   +1 more source

Cardiovascular Risk of Romosozumab vs. Teriparatide: A Cohort Study Using Japan’s National Claims Database

Clinical Pharmacology &Therapeutics, EarlyView.
Disproportionality analyses suggested a cardiovascular risk signal for romosozumab, while statistically significant associations were not found in the real‐world database studies. Therefore, a larger comparative study was necessary to examine this signal.
Hotaka Maruyama, Eiko Iwasa, Shinya Watanabe, Tomoaki Hasegawa, Kazuhiro Kajiyama, Taihei Tanaka   +5 more
wiley   +1 more source

Predicting Early Dysphagia in Acute Ischemic Stroke Using an Explainable Machine Learning Model. [PDF]

Int J Gen Med
Li Y, Yu S, Yu X, Tian B, Tang J, Qu H, Zhang Y.   +6 more
europepmc   +1 more source

Rehabilitation of pharyngeal dysphagia and spastic dysarthria following acute ischemic stroke: a case study

R. Johnsirani, V. Jaya, S. Janani, P. Thrisha   +3 more
openalex   +2 more sources