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Nature Reviews Disease Primers, 2021 Acute kidney injury (AKI) is defined by a sudden loss of excretory kidney function. AKI is part of a range of conditions summarized as acute kidney diseases and disorders (AKD), in which slow deterioration of kidney function or persistent kidney dysfunction is associated with an irreversible loss of kidney cells and nephrons, which can lead to chronic ...
John A. Kellum +5 more
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Nederlands tijdschrift voor geneeskunde, 2012 - 'Acute kidney injury' is modern terminology for a sudden decline in kidney function, and is defined by the RIFLE classification (RIFLE is an acronym for Risk, Injury, Failure, Loss and End-stage kidney disease).- Acute kidney injury occurs as a result of the combination of reduced perfusion in the kidney, systemic inflammation, and the administration
Hageman, D. +4 more
exaly +14 more sources
The LancetAcute kidney injury (AKI) is a common, heterogeneous, multifactorial condition, which is part of the overarching syndrome of acute kidney diseases and disorders. This condition's incidence highest in low-income and middle-income countries. In the short term, AKI is associated with increased mortality, an increased risk of complications, extended stays ...
Marlies, Ostermann +5 more
exaly +6 more sources
Clinical Medicine, 2015 Acute kidney injury (AKI) - an abrupt deterioration in renal function - causes a rise in serum creatinine (SCr) or fall in urine output. It is common, occurring in up to 20% of hospital admissions. Importantly, even small rises in SCr are associated with increased risk of death and longer hospital stays.
Catherine E. Langston, Adam E. Eatroff
+11 more sources
Annual Review of Medicine, 2016 Acute kidney injury (AKI) is a global public health concern associated with high morbidity, mortality, and healthcare costs. Other than dialysis, no therapeutic interventions reliably improve survival, limit injury, or speed recovery. Despite recognized shortcomings of in vivo animal models, the underlying pathophysiology of AKI and its consequence ...
Anna, Zuk, Joseph V, Bonventre
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Primary Care: Clinics in Office Practice, 2020 Acute kidney injury (AKI) is defined as an increase in serum creatinine or a decrease in urine output over hours to days. A thorough history and physical examination can help categorize the underlying cause as prerenal, intrinsic renal, or postrenal.
Jackcy, Jacob +2 more
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Danger in the jungle:sensible care to reduce avoidable acute kidney injury in hospitalized children [PDF]
, 2020 When children require hospital admission, many receive medications with nephrotoxic potential. As such, this can translate into an increased risk of acute kidney injury.
Bagshaw, Sean M. +2 more
core +2 more sources
Journal of Injury and Violence Research, 2014 Acute kidney injury is a frequent and serious complication in hospitalized patients. Mortality rates have not substantially been decreased during the last 20 years. In most patients AKI results from transient renal hypoperfusion or ischemia. The consequences include tubular cell dysfunction/damage, inflammation of the organ, and post-ischemic ...
Patschan, Daniel, Müller, Gerhard Anton
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Nursing Standard, 2013 Acute kidney injury (AKI) represents a medical emergency associated with poor clinical outcomes. The international guideline group Kidney Disease: Improving Global Outcomes (KDIGO) has defined AKI according to rises in serum creatinine and/or reductions in urine output.
S, Anathhanam, A J P, Lewington
openaire +4 more sources
Jornal de Pediatria, 2021 Objective: To assess the prevalence of acute kidney injury in pediatric intensive care unit according to diagnostic criteria – pediatric risk, injury, failure, loss, end-stage renal disease, Acute Kidney Injury Network and Acute Kidney Injury Work Group,
Cibelle Ferreira Louzada +1 more
doaj +1 more source