A new outlook towards kidney injuries [PDF]
Acute and chronic progression of injury to the kidney leads to the failure of the renal system and has become an increasingly important cause of morbidity and mortality.
Mahesh Satwekar, Abhijeet Satwekar
core +1 more source
Do acute elevations of serum creatinine in primary care engender an increased mortality risk? [PDF]
Background: The significant impact Acute Kidney Injury (AKI) has on patient morbidity and mortality emphasizes the need for early recognition and effective treatment.
Paul Bassett +13 more
core +2 more sources
Xenobiotic metabolism: the effect of acute kidney injury on non-renal drug clearance and hepatic drug metabolism. [PDF]
Acute kidney injury (AKI) is a common complication of critical illness, and evidence is emerging that suggests AKI disrupts the function of other organs.
John Dixon +7 more
core +1 more source
Risk of postoperative acute kidney injury in patients undergoing orthopaedic surgery—development and validation of a risk score and effect of acute kidney injury on survival:observational cohort study [PDF]
Objective: To develop and externally validate a risk score to predict post-operative Acute Kidney Injury (AKI) in patients undergoing orthopaedic surgery and to examine the impact of AKI on both short and long term survival.
Deshmukh, Harshal +23 more
core +1 more source
Estimated glomerular filtration rate correlates poorly with four-hour creatinine clearance in critically ill patients with acute kidney injury. [PDF]
Introduction. RIFLE and AKIN provide a standardised classification of acute kidney injury (AKI), but their categorical rather than continuous nature restricts their use to a research tool. A more accurate real-time description of renal function in AKI is
Iain A. M. MacPhee +5 more
core +1 more source
Acute kidney injury in children with cancer admitted in an intensive care unit
Objective: Evaluating the association between acute kidney injury and death in critically ill children with oncological diseases admitted in an intensive care unit (ICU). Material and Methods: Unicentric cohort study,
Giovanna Soldatelli Borsato +5 more
core +1 more source
Discovery and validation of cell cycle arrest biomarkers in human acute kidney injury [PDF]
Introduction: Acute kidney injury (AKI) can evolve quickly and clinical measures of function often fail to detect AKI at a time when interventions are likely to provide benefit.
Vinsonneau, Christophe +144 more
core +1 more source
Growth differentiation factor-15 preserves Klotho expression in acute kidney injury and kidney fibrosis [PDF]
Growth differentiation factor-15 (GDF15) is a member of the GDF subfamily with potential kidney protective functions. Here, we explored the impact of GDF15 on the expression of the kidney protective factor Klotho in models of acute kidney injury and ...
Ceballos, Maria I. +22 more
core +1 more source
Acute Kidney Injury in Acute Stroke
Madam, Acute kidney injury (AKI) in acute stroke setting has recently gained importance as a relatively common complication and its associated adverse clinical outcomes in this population. Early diagnosis of AKI in its potentially reversible stages is of utmost importance, especially in a resource-limited setting like ours, and may improve outcomes in ...
Sonia, Yaqub, Ayesha, Aziz
openaire +2 more sources
Acute kidney injury: an acceptable risk of treatment with renin-angiotensin system blockade in primary care? [PDF]
Background: Use of renin-angiotensin system (RAS) blockade has become increasingly widespread driven by evidence-based guidance. There is concern about the role of these agents in the genesis of avoidable acute kidney injury (AKI).
Jean Irving +7 more
core +2 more sources

