Results 41 to 50 of about 400,419 (299)

Indexed oxygen delivery during pediatric cardiopulmonary bypass is a modifiable risk factor for postoperative acute kidney injury

The Journal of ExtraCorporeal Technology, 2023
Background: Acute kidney injury after pediatric cardiac surgery is a common complication with few established modifiable risk factors. We sought to characterize whether indexed oxygen delivery during cardiopulmonary bypass was associated with ...
Dreher Molly, Min Jungwon, Mavroudis Constantine, Ryba Douglas, Ostapenko Svetlana, Melchior Richard, Rosenthal Tami, Nuri Muhammad, Blinder Joshua   +8 more
doaj   +1 more source

A new outlook towards kidney injuries

, 2012
Acute and chronic progression of injury to the kidney leads to the failure of the renal system and has become an increasingly important cause of morbidity and mortality.
Mahesh Satwekar, Abhijeet Satwekar
core   +1 more source

Roles of DNA damage in renal tubular epithelial cells injury

Frontiers in Physiology, 2023
The prevalence of renal diseases including acute kidney injury (AKI) and chronic kidney disease (CKD) is increasing worldwide. However, the pathogenesis of most renal diseases is still unclear and effective treatments are still lacking.
Peipei Wang, Peipei Wang, Peipei Wang, Jing Ouyang, Jing Ouyang, Jing Ouyang, Zhanjun Jia, Zhanjun Jia, Zhanjun Jia, Aihua Zhang, Aihua Zhang, Aihua Zhang, Yunwen Yang, Yunwen Yang, Yunwen Yang   +14 more
doaj   +1 more source

Advanced age affects the outcome-predictive power of RIFLE classification in geriatric patients with acute kidney injury

, 2014
The RIFLE (risk, injury, failure, loss, and end-stage) classification is widely used to gauge the severity of acute kidney injury, but its efficacy has not been formally tested in geriatric patients.
Chao, Chia-Ter;Wu, Vin-Cent;Lai, Chun-Fu;Shiao, Chih-Chung;Huang, Tao-Min;Wu, Pei-Chen;Tsai, I-Jung;Hou, Chun-Cheng;Wang, Wei-Jie;Tsai, Hung-Bin;Lin, Yu-Feng;Chiang, Wen-Chih;Lin, Shuei-Liong;Tsai, Pi-Ru;Ko, Wen-Je;Wu, Ming-Shiou;Wu, Kuan-Dun, 吳明修 ;林裕峯 ;賴俊夫 ;蔡宜蓉 ;趙家德 ;姜文智 ;柯文哲 ;吳允升 ;吳寬墩 ;黃道民 ;林水龍 ;蔡壁如 ;蔡宏斌   +1 more
core   +1 more source

The prevalence and identification of chronic kidney disease in Switzerland [PDF]

, 2015
BACKGROUND: Chronic kidney disease (CKD) is characterized by a gradual loss of kidney function. Patients in early CKD stages are often asymptomatic or show non-specific symptoms.
Tomonaga, Yuki
core   +1 more source

Acute kidney injury in Australia: a first national snapshot [PDF]

, 2015
Overview Acute kidney injury (AKI) is increasing in incidence globally. This report presents the first national statistical snapshot on AKI and its impact in Australia.
Australian Institute of Health and Welfare
core  

Xenobiotic metabolism: the effect of acute kidney injury on non-renal drug clearance and hepatic drug metabolism.

, 2014
Acute kidney injury (AKI) is a common complication of critical illness, and evidence is emerging that suggests AKI disrupts the function of other organs.
John Dixon, Philips, B, Dixon, J, Lane, K, Macphee, I, Katie Lane, Barbara Philips, Iain MacPhee   +7 more
core   +1 more source

Perioperative Acute Kidney Injury [PDF]

, 2023
Acute kidney injury (AKI) is one of the important complications of the perioperative period, and associated with increased risk of chronic kidney disease, renal replacement therapy requirements, increased cost, and risk of mortality. In this overview, we
Lee Goeddel, Ozan Akça
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Heart failure subtype after acute kidney injury

BMC Nephrology
Introduction Acute kidney injury (AKI) is associated with increased risk of heart failure (HF). Determining the type of HF experienced by AKI survivors (heart failure with preserved or reduced ejection fraction, HFpEF or HFrEF) could suggest potential ...
Bethany C. Birkelo, Evan Brittain, Andrew Guide, Robert A. Greevy, Michael E. Matheny, Jeffrey Annis, Trey Richardson, Sarah Faubel, Edward D. Siew   +8 more
doaj   +1 more source