Results 61 to 70 of about 400,419 (299)
Genetics & Applications, 2019 Acute kidney injury is a common condition associated with longer hospital stay and increased mortality. Kidney injury molecule-1 (KIM-1) is one of the early and sensitive biomarkers for acute kidney injury diagnosis.
Hajar Karaali, Jamilah Borjac
doaj +1 more source
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
Acute Kidney Injury in the Elderly [PDF]
Clinics in Geriatric Medicine, 2009 The aging kidney undergoes several important anatomic and physiologic changes that increase the risk of acute kidney injury (formerly acute renal failure) in the elderly. This article reviews these changes and discusses the diagnoses frequently encountered in the elderly patient with acute kidney injury.
Khaled, Abdel-Kader, Paul M, Palevsky
openaire +2 more sources
A Case of Acute Kidney Injury with Marked Hyperuricemia During Mizoribine Administration [PDF]
, 2012 A 52-year-old woman was diagnosed with Blau syndrome and rheumatoid arthritis and was treated with prednisolone and methotrexate. Joint pain and skin ulcers were poorly controlled; therefore, mizoribine (MZ; 150 mg/day) was administered once daily from ...
Nishino, Tomoya +6 more
core +1 more source
The management and diagnosis of rhabdomyolysis induced acute kidney injury: a case study [PDF]
, 2022 Rhabdomyolysis is characterised by a rapid dissolution of damaged or injured skeletal muscle which can be caused by a multitude of different mechanisms. It can range in severity from mild to severe leading to multi organ failure and death. Rhabdomyolysis
Mortimore, G., Torr, L.
core +1 more source
FEBS Open Bio, EarlyView.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
Review of the limitations of current biomarkers in acute kidney injury clinical practices
SAGE Open MedicineAcute kidney injury is a prevalent disease in hospitalized patients and is continuously increasing worldwide. Various efforts have been made to define and classify acute kidney injury to understand the progression of this disease. Furthermore, deviations
Kendra B Bufkin +2 more
doaj +1 more source
The neuronal guidance protein netrin-1 reduces alveolar inflammation in a porcine model of acute lung injury [PDF]
, 2010 Introduction: Acute lung injury (ALI) is an inflammatory disorder of pulmonary or extrapulmonary origin. We have previously demonstrated that netrin-1 dampens murine ALI, and in an attempt to advance this finding into future clinical practice we ...
Kristina Waibler +17 more
core +1 more source
FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
Emergent CT angiography and risk of contrast-induced acute kidney injury in acute ischaemic stroke
, 2016 Objectives: Emergent computed tomography angiography with contrast is commonly performed for acute ischaemic stroke, but potentially delayed pending admission renal function assessment due to purported risk of contrast-induced acute kidney injury.
Prakash Paliwal +10 more
core +1 more source