Results 1 to 10 of about 501,395 (191)
Ultrasmall Nanodots with Dual Anti-Ferropototic Effect for Acute Kidney Injury Therapy. [PDF]
Adv Sci (Weinh)Ferroptosis is known to mediate the pathogenesis of chemotherapeutic drug‐induced acute kidney injury (AKI); however, leveraging the benefits of ferroptosis‐based treatments for nephroprotection remains challenging.
Zeng F +11 more
europepmc +2 more sources
Renal replacement therapy in acute kidney injury. [PDF]
The Lancet, 2020 Zhenxing Lu +3 more
semanticscholar +7 more sources
Novel Therapies for Acute Kidney Injury [PDF]
Kidney International Reports, 2017 Acute kidney injury (AKI) is a common disease with a complex pathophysiology. The old paradigm of identifying renal injury based on location-prerenal, intrarenal, and postrenal-is now being supplanted with a new paradigm based on observable kidney injury patterns. The pathophysiology of AKI on a molecular and microanatomical level includes inflammation,
Huaizhen Chen, Laurence William Busse
openaire +3 more sources
Renal Replacement Therapy for Acute Kidney Injury [PDF]
Nephron Clinical Practice, 2009 The treatment of established acute kidney injury (AKI) is largely supportive in nature. Renal replacement therapy remains the cornerstone of management for the minority of patients who have severe AKI. Optimization of renal replacement therapy may modulate the high mortality associated with AKI. Recent trials indicated that continuous renal replacement
Heather, Fieghen +2 more
openaire +2 more sources
The Lancet, 2021 BACKGROUND Delaying renal replacement therapy (RRT) for some time in critically ill patients with severe acute kidney injury and no severe complication is safe and allows optimisation of the use of medical devices.
S. Gaudry +43 more
semanticscholar +1 more source
Macrophages in Renal Injury, Repair, Fibrosis Following Acute Kidney Injury and Targeted Therapy
Frontiers in Immunology, 2022 Acute kidney injury (AKI) is a renal disease with a high incidence and mortality. Currently, there are no targeted therapeutics for preventing and treating AKI.
Hui Chen, Na Liu, S. Zhuang
semanticscholar +1 more source
Timing of Kidney Replacement Therapy in Acute Kidney Injury [PDF]
Clinical Journal of the American Society of Nephrology, 2018 AKI is a common complication with an increasing incidence and a higher risk of short- and long-term complications ([1][1]). Kidney replacement therapy (KRT) is often required in patients with severe AKI who develop clinical and/or metabolic complications.
Alexander, Zarbock, Ravindra L, Mehta
openaire +2 more sources
Role of Mitochondrial Therapy for Ischemic-Reperfusion Injury and Acute Kidney Injury
Nephron, 2021 Acute kidney injury (AKI) is a common clinical disorder associated with decline in renal function because of ischemic and nephrotoxic insults. The pathophysiology of AKI involves multiple cellular mechanisms, such as kidney parenchymal cell (epithelial ...
N. Pabla, A. Bajwa
semanticscholar +1 more source
Cell-Based Therapies in Acute Kidney Injury (AKI) [PDF]
Kidney and Blood Pressure Research, 2018 Acute kidney injury frequently occurs in hospitalized patients all over the world. The prognosis remains poor since specific therapies for promoting kidney regeneration/repair are still missing. In recent years cell-based strategies have improved AKI outcomes under experimental circumstances.
Patschan, Daniel +3 more
openaire +3 more sources
Impact of acute kidney injury exposure period among liver transplantation patients [PDF]
, 2013 Background: Acute kidney injury is a common complication of liver transplantation. in this single-centre retrospective observational study, we investigated the impact of acute kidney disease on liver recipient survival.Methods: the study population ...
Batista, Marcelo Costa +8 more
core +2 more sources