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Novel Therapies for Acute Kidney Injury [PDF]

open access: yesKidney International Reports, 2017
Acute kidney injury (AKI) is a common disease with a complex pathophysiology. The old paradigm of identifying renal injury based on location-prerenal, intrarenal, and postrenal-is now being supplanted with a new paradigm based on observable kidney injury patterns. The pathophysiology of AKI on a molecular and microanatomical level includes inflammation,
Huaizhen Chen, Laurence William Busse
openaire   +3 more sources

Renal Replacement Therapy for Acute Kidney Injury [PDF]

open access: yesNephron Clinical Practice, 2009
The treatment of established acute kidney injury (AKI) is largely supportive in nature. Renal replacement therapy remains the cornerstone of management for the minority of patients who have severe AKI. Optimization of renal replacement therapy may modulate the high mortality associated with AKI. Recent trials indicated that continuous renal replacement
Heather, Fieghen   +2 more
openaire   +2 more sources

Timing of Kidney Replacement Therapy in Acute Kidney Injury [PDF]

open access: yesClinical Journal of the American Society of Nephrology, 2018
AKI is a common complication with an increasing incidence and a higher risk of short- and long-term complications ([1][1]). Kidney replacement therapy (KRT) is often required in patients with severe AKI who develop clinical and/or metabolic complications.
Alexander, Zarbock, Ravindra L, Mehta
openaire   +2 more sources

Cell-Based Therapies in Acute Kidney Injury (AKI) [PDF]

open access: yesKidney and Blood Pressure Research, 2018
Acute kidney injury frequently occurs in hospitalized patients all over the world. The prognosis remains poor since specific therapies for promoting kidney regeneration/repair are still missing. In recent years cell-based strategies have improved AKI outcomes under experimental circumstances.
Patschan, Daniel   +3 more
openaire   +3 more sources

Impact of acute kidney injury exposure period among liver transplantation patients [PDF]

open access: yes, 2013
Background: Acute kidney injury is a common complication of liver transplantation. in this single-centre retrospective observational study, we investigated the impact of acute kidney disease on liver recipient survival.Methods: the study population ...
Batista, Marcelo Costa   +8 more
core   +2 more sources

Nutrition Support in Acute Kidney Injury [PDF]

open access: yes, 2011
Acute kidney injury is a frequent complication affecting many hospitalized patients and is associated with increased morbidity and mortality. Acute kidney injury often occurs in conjunction with critical illness, which is a hypermetabolic state ...
Alkhunaizi AM   +15 more
core   +2 more sources

Do acute elevations of serum creatinine in primary care engender an increased mortality risk? [PDF]

open access: yes, 2014
Background: The significant impact Acute Kidney Injury (AKI) has on patient morbidity and mortality emphasizes the need for early recognition and effective treatment.
A Bottle   +35 more
core   +1 more source

Renal Replacement Therapy in Acute Kidney Injury [PDF]

open access: yesAdvances in Chronic Kidney Disease, 2013
Although the use of renal replacement therapy (RRT) to support critically ill patients with acute kidney injury (AKI) has become routine, many of the fundamental questions regarding optimal management of RRT remain. This review summarizes current evidence regarding the timing of initiation of RRT, the selection of the specific modality of RRT, and ...
openaire   +2 more sources

Nephrologist Interventions to Avoid Kidney Replacement Therapy in Acute Kidney Injury [PDF]

open access: yesKidney and Blood Pressure Research, 2021
<b><i>Background:</i></b> Based on the pathophysiology of acute kidney injury (AKI), it is plausible that certain early interventions by the nephrologist could influence its trajectory. In this study, we investigated the impact of 5 early nephrology interventions on starting kidney replacement therapy (KRT), AKI progression, and
Jonathan S. Chávez-Íñiguez   +10 more
openaire   +3 more sources

Renal replacement therapy in acute kidney injury – Authors' reply [PDF]

open access: yesThe Lancet, 2020
International ...
Gaudry, Stéphane   +4 more
openaire   +3 more sources

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