Results 1 to 10 of about 1,893,034 (314)

Clinicopathologic Findings of Spontaneous Leukemia in 9 Pet African Hedgehogs (Atelerix Albiventris)

Frontiers in Veterinary Science, 2020
Previous reports of leukemia in hedgehogs are limited. We describe clinicopathologic features of leukemia in 9 hedgehogs, including eosinophilic leukemia (n = 3) and acute leukemia/leukemic phase of lymphoma (n = 6).
Iori Koizumi, Daniela Hernandez-Muguiro, Shelley Ann Ash Chu, Tracy Stokol, Midori Goto Asakawa   +4 more
doaj   +1 more source

Patient Involvement in Health Technology Assessments: Lessons for EU Joint Clinical Assessments

Journal of Market Access & Health Policy
Patient involvement in health technology assessment (HTA) processes is increasingly recognized as pivotal for informed, equitable, and patient-relevant health care decision-making.
Anne-Pierre Pickaert
doaj   +1 more source

Ferroptosis in acute leukemia

Chinese Medical Journal, 2023
Abstract Ferroptosis is an iron-dependent cell death pathway that is different from apoptosis, pyroptosis, and necrosis. The main characteristics of ferroptosis are the Fenton reaction mediated by intracellular free divalent iron ions, lipid peroxidation of cell membrane lipids, and inhibition of the anti-lipid peroxidation ...
Tianxin Lyu, Xudong Li, Yongping Song, Ting Gao, Xiuyuan Hao   +4 more
openaire   +3 more sources

T-cell-replete haploidentical transplantation versus autologous stem cell transplantation in adult acute leukemia: a matched pair analysis

Haematologica, 2015
Adult patients with acute leukemia in need of a transplant but without a genoidentical donor are usually considered upfront for transplantation with stem cells from any other allogeneic source, rather than autologous stem cell transplantation.
Norbert-Claude Gorin, Myriam Labopin, Simona Piemontese, William Arcese, Stella Santarone, He Huang, Giovanna Meloni, Felicetto Ferrara, Dietrich Beelen, Miguel Sanz, Andrea Bacigalupo, Fabio Ciceri, Audrey Mailhol, Arnon Nagler, Mohamad Mohty   +14 more
doaj   +1 more source

Proteomic Comparison of Acute Myeloid Leukemia Cells and Normal CD34⁺ Bone Marrow Cells: Studies of Leukemia Cell Differentiation and Regulation of Iron Metabolism/Ferroptosis

Proteomes
Acute myeloid leukemia (AML) is an aggressive bone marrow malignancy that can be cured only by intensive chemotherapy possibly combined with allogeneic stem cell transplantation.
Frode Selheim, Elise Aasebø, Håkon Reikvam, Øystein Bruserud, Maria Hernandez-Valladares   +4 more
doaj   +1 more source

Impact of leukemia subtype and demographics on patient quality of life in 76 countries: a cross-sectional study

Frontiers in Hematology
BackgroundDisease-specific factors associated with decreased quality of life (QoL) in patients with leukemia have not been studied in a large-scale, global, observational study.MethodsThis cross-sectional study used the validated Hematological Malignancy
Sam Salek, Samantha Nier, Zack Pemberton-Whiteley, Tatyana Ionova, Giuseppe Ianni, Giovanni Tripepi, Nick York, Nicole Schroeter, Kathryn Huntley, Michael Rynne, Denis Costello, Lidija Pecova, Esther Natalie Oliva   +12 more
doaj   +1 more source

Clinical and biological characteristics of adult biphenotypic acute leukemia in comparison with that of acute myeloid leukemia and acute lymphoblastic leukemia: a case series of a Chinese population

Haematologica, 2009
Background Biphenotypic acute leukemia is a rare disorder that is difficult to diagnose. It displays features of both myeloid and lymphoid lineage. There is still a lack of studies in biphenotypic acute leukemia in a Chinese population. We present here a
Xiao-Qian Xu, Jian-Min Wang, Shu-Qing Lü, Li Chen, Jian-Min Yang, Wei-Ping Zhang, Xian-Min Song, Jun Hou, Xiong Ni, Hui-Ying Qiu   +9 more
doaj   +1 more source

Frequency of polymorphisms in the IKZF1 and CDKN2A/2B genes and descriptive analysis in pediatric patients with acute lymphoblastic leukemia: a multicenter hospital-based prevalence study in Rio De Janeiro

BMC Cancer
Background Acute lymphoblastic leukemia (ALL) is the most common childhood cancer, and B-cell ALL (B-ALL) is the most common subtype. The understanding of ALL has advanced significantly in recent years due to genomic sequencing, which has made it ...
Ariadne da Rocha Figueiredo, Thayana da Conceição Barbosa, Mariana Emerenciano, Marcelo Gerardin Poirot Land   +3 more
doaj   +1 more source

Disease and treatment burden in patients with leukaemia: family members/partner perspective

Frontiers in Hematology
BackgroundLeukaemia patients require comprehensive care, including treatment, hospital visits, and family support. An awareness of the impact of leukaemia on family members is crucial. The Acute Leukemia Advocates Network, Chronic Lymphoid Leukemia (CLL)
Esther Natalie Oliva, Tatyana Ionova, Samantha Nier, Zack Pemberton-Whiteley, Zack Pemberton-Whiteley, Nick York, Denis Costello, Sam Salek   +7 more
doaj   +1 more source

RNA INTERFERENCE (RNAI): AN EFFECTIVE WAY TO DEVELOP RATIONAL COMBINATION THERAPIES WITH HYPOMETHYLATING AGENTS IN ACUTE LEUKAEMIAS AND MYELODYSPLASTIC SYNDROME [PDF]

European Medical Journal Hematology, 2013
Therapeutic progress in aggressive myeloid malignancies such as acute myeloid leukaemia (AML), myelodysplastic syndrome (MDS) and advanced myeloproliferative neoplasm (MPNs) has been slow.
Raoul Tibes
doaj