Results 21 to 30 of about 1,893,034 (314)
In vivo imaging enables high resolution preclinical trials on patients' leukemia cells growing in mice. [PDF]
, 2012 Xenograft mouse models represent helpful tools for preclinical studies on human tumors. For modeling the complexity of the human disease, primary tumor cells are by far superior to established cell lines.
zur Stadt, Udo +51 more
core +2 more sources
Optimization of the indications for allogeneic stem cell transplantation in Acute Myeloid Leukemia based on interactive diagnostic strategies [PDF]
, 2011 The indications for allogeneic stem cell transplantation (SCT) in Acute Myeloid Leukemia (AML) represent a real challenge due to the clinical and genetic heterogeneity of the disorder.
Hartwig, Maite +5 more
core +1 more source
Cancer Medicine, 2019 Deferasirox is an oral iron‐chelating agent having possible antileukemia and immune modulatory effects. Few reports have evaluated deferasirox in the setting of allogeneic hematopoietic stem cell transplantation (allo‐HSCT). We investigated the impact of
Byung‐Sik Cho +14 more
doaj +1 more source
Hematology, Transfusion and Cell Therapy, 2021 ETV6-RUNX1 and BCR-ABL1 are recurrent primary events in pediatric B-cell precursor acute lymphoblastic leukemia (B-ALL), being the former the most common one.
TC Barbosa +6 more
doaj +1 more source
Journal of Hematology & Oncology, 2016 Background Data comparing fully matched and mismatched-unrelated-donor (M- and mM-URD) allogeneic hematopoietic stem cell transplant (allo-SCT) following reduced intensity conditioning regimens for acute myeloid leukemia are limited.
Marie T. Rubio +15 more
doaj +1 more source
Acute Myeloid Leukemia and Acute Promyelocytic Leukemia
Hematology, 2003 AbstractThe therapeutic approach to the patient with acute myeloid leukemia (AML) currently evolves toward new frontiers. This is particularly apparent from the entree of high-throughput diagnostic technologies and the identification of prognostic and therapeutic targets, the introduction of therapies in genetically defined subgroups of AML, as well as
Bob, Löwenberg +2 more
openaire +2 more sources
Acute Leukemia in Children [PDF]
BioMed Research International, 2015 Acute lymphoblastic leukemia (ALL) is the most common cancer during childhood. Nevertheless, in recent years there have been marked improvements in treatment and consequent survival. There are a number of patients that experience relapses and patients that cannot be cured. In this special issue different aspects relating to factors influencing the best
Mejía-Aranguré, Juan Manuel +1 more
openaire +2 more sources
Gene rearrangements in bone marrow cells of patients with acute myelogenous leukemia [PDF]
, 2000 At diagnosis, clonal gene rearrangement probes {[}retinoic acid receptor (RAR)-alpha, major breakpoint cluster region (M-bcr), immunoglobulin (Ig)-JH, T cell receptor (TcR)-beta, myeloid lymphoid leukemia (MLL) or cytokine genes (GM-CSF, G-CSF, IL-3 ...
Mittermueller, J. +11 more
core +1 more source
Journal of Hematology & Oncology, 2023 There are situations where non-first-degree (NFD) related donors have to be considered as alternatives to first-degree (FD) related donors for haploidentical hematopoietic cell transplantation (HAPLO).
Yishan Ye +15 more
doaj +1 more source
Women's Health, 2010 The treatment and survival outcome of acute leukemia in women is generally similar to that of men. However, acute leukemia in women poses additional challenges in clinical practice. In addition to important precautions during therapy, such as prevention of abnormal uterine bleeding in premenopausal women and therapy during pregnancy, women who are ...
LO COCO, FRANCESCO +2 more
openaire +4 more sources