Results 11 to 20 of about 3,163,010 (367)
Acute Leukemia in Children [PDF]
BioMed Research International, 2015 Acute lymphoblastic leukemia (ALL) is the most common cancer during childhood. Nevertheless, in recent years there have been marked improvements in treatment and consequent survival. There are a number of patients that experience relapses and patients that cannot be cured. In this special issue different aspects relating to factors influencing the best
Juan Manuel Mejía-Aranguré +1 more
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Focus on acute leukemias [PDF]
Cancer Cell, 2002 Progress toward cure of acute leukemia is likely to occur with new therapies directed at specific molecular targets, such as BCR/ABL, FLT3, RAS, and the NCor/HDAC complex. This goal may be facilitated by modern genomic approaches to acute leukemia, including use of DNA microarray and proteomic strategies for identification of novel targets and ...
Martin S. Tallman, D. Gary Gilliland
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Blood, 2016 The World Health Organization (WHO) classification of tumors of the hematopoietic and lymphoid tissues was last updated in 2008. Since then, there have been numerous advances in the identification of unique biomarkers associated with some myeloid ...
D. Arber +8 more
semanticscholar +1 more source
Methods in Molecular Biology, 2018 Advances in our understanding of the pathophysiology of acute myeloid leukemia (AML) have not yet led to major improvements in disease-free and overall survival of adults with this disease.
G. Ossenkoppele
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Blood, 2009 Recently the World Health Organization (WHO), in collaboration with the European Association for Haematopathology and the Society for Hematopathology, published a revised and updated edition of the WHO Classification of Tumors of the Hematopoietic and ...
J. Vardiman +10 more
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Acute Myeloid Leukemia and Acute Promyelocytic Leukemia
Hematology, 2003 AbstractThe therapeutic approach to the patient with acute myeloid leukemia (AML) currently evolves toward new frontiers. This is particularly apparent from the entree of high-throughput diagnostic technologies and the identification of prognostic and therapeutic targets, the introduction of therapies in genetically defined subgroups of AML, as well as
Martin S. Tallman +2 more
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Genomic Classification and Prognosis in Acute Myeloid Leukemia.
New England Journal of Medicine, 2016 BACKGROUND Recent studies have provided a detailed census of genes that are mutated in acute myeloid leukemia (AML). Our next challenge is to understand how this genetic diversity defines the pathophysiology of AML and informs clinical practice ...
E. Papaemmanuil +26 more
semanticscholar +1 more source
Haematologica, 2023 Pediatric acute myeloid leukemia (AML) is a highly heterogeneous disease making standardized measurable residual disease (MRD) assessment challenging. Currently, patient-specific DNA-based assays are only rarely applied for MRD assessment in pediatric ...
Margarita Maurer-Granofszky +12 more
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Journal of Hematology & Oncology, 2016 Background Data comparing fully matched and mismatched-unrelated-donor (M- and mM-URD) allogeneic hematopoietic stem cell transplant (allo-SCT) following reduced intensity conditioning regimens for acute myeloid leukemia are limited.
Marie T. Rubio +15 more
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Quaternion-Valued Convolutional Neural Network Applied for Acute Lymphoblastic Leukemia Diagnosis [PDF]
A. Britto and K. Valdivia Delgado (Eds.): BRACIS 2021, LNAI 13074,
pp. 280-293, 2021. Springer Nature Switzerland AG 2021, 2021 The field of neural networks has seen significant advances in recent years with the development of deep and convolutional neural networks. Although many of the current works address real-valued models, recent studies reveal that neural networks with hypercomplex-valued parameters can better capture, generalize, and represent the complexity of ...
arxiv +1 more source