Results 11 to 20 of about 310,818 (241)
Chemotherapeutic trial for acute leukemia in Iraq [PDF]
Chemotherapeutic trial for acute leukemia in Iraq
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Understanding Quality of Life in Patients With Acute Leukemia, a Global Survey
Purpose: The Acute Leukemia Advocates Network (ALAN) sought to determine which factors are most associated with poor quality of life (QoL) in patients with acute leukemia and to determine key issues and unmet needs through administration of an online ...
Zack Pemberton-Whiteley+9 more
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Socioeconomic cost of AML in Sweden—A population‐based study using multiple nation‐wide registers
Acute myeloid leukemia (AML) is associated with a high economic and clinical burden. Recently novel therapies have been added to standard treatment regimens. Here, we evaluated the economic impact of AML up until the introduction of these novel therapies.
Emma Hernlund+6 more
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Expression of the apelinergic system and its influence on functional properties of tumor cells
mall peptide Apelin and its cognate receptor APJ, are known to play a role in tumor angiogenesis and overall cancer progession. Certain authors suggest that the Apelin receptor is also a factor in cancer immunotherapy.
Zoran Knezevic+5 more
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Abstract Ferroptosis is an iron-dependent cell death pathway that is different from apoptosis, pyroptosis, and necrosis. The main characteristics of ferroptosis are the Fenton reaction mediated by intracellular free divalent iron ions, lipid peroxidation of cell membrane lipids, and inhibition of the anti-lipid peroxidation ...
Tianxin Lyu+4 more
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In vivo imaging enables high resolution preclinical trials on patients' leukemia cells growing in mice. [PDF]
Xenograft mouse models represent helpful tools for preclinical studies on human tumors. For modeling the complexity of the human disease, primary tumor cells are by far superior to established cell lines.
Brentjens, Renier J.+12 more
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Acute Promyelocytic Leukemia [PDF]
Acute promyelocytic leukemia (APL) is a distinct subtype of acute myeloid leukemia (AML) cytogenetically characterized by a balanced reciprocal translocation between chromosomes 15 and 17, which results in the fusion between the promyelocytic leukemia (PML) gene and retinoic acid receptor-α (RARα) [...]
Xavier Thomas, Maël Heiblig
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Acute Leukemia in Children [PDF]
Acute lymphoblastic leukemia (ALL) is the most common cancer during childhood. Nevertheless, in recent years there have been marked improvements in treatment and consequent survival. There are a number of patients that experience relapses and patients that cannot be cured. In this special issue different aspects relating to factors influencing the best
Juan Manuel Mejía-Aranguré+1 more
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Focus on acute leukemias [PDF]
Progress toward cure of acute leukemia is likely to occur with new therapies directed at specific molecular targets, such as BCR/ABL, FLT3, RAS, and the NCor/HDAC complex. This goal may be facilitated by modern genomic approaches to acute leukemia, including use of DNA microarray and proteomic strategies for identification of novel targets and ...
Martin S. Tallman, D. Gary Gilliland
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Fatal lymphoproliferation and acute monocytic leukemia-like disease following infectious mononucleosis in the elderly [PDF]
Three elderly patients are reported, in whom serologically confirmed recent infectious mononucleosis is followed by fatal lymphoproliferation (case 1), by acute monocytic leukemia (case 2), and by acute probably monocytic leukemia (case 3)
Deinhardt, F.+5 more
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