Results 191 to 200 of about 3,808,290 (359)

Post-Transplant Relapse in Acute Leukemia: Comparative Value of MRD and Chimerism. [PDF]

Mediterr J Hematol Infect Dis
Öksüz SBT, Seval GC, Dalva K, Toprak SK.   +3 more
europepmc   +1 more source

Combination Immunotherapy as a Promising Strategy to Overcome Immunotherapy Resistance: From Emergence to Next‐Generation Approaches

Advanced Science, EarlyView.
This review examines emerging combination immunotherapy strategies tailored to distinct tumor microenvironments and highlights next‐generation biomarkers that guide response prediction and treatment personalization. It integrates lessons from unsuccessful trials, addresses toxicity challenges, and outlines approaches for early biomarker discovery and ...
Asmita Pandey, Sudhir Kumar Rai, Li Ma, Lauren Higa, Vedbar Khadka, Hua Yang, Youping Deng   +6 more
wiley   +1 more source

Breakthrough Varicella During Chemotherapy in Two Vaccinated Children With Acute Leukemia. [PDF]

Cureus
Kosa H, Oyama C, Nakashima S, Taketani T.   +3 more
europepmc   +1 more source

PAX5-driven subtypes of B-progenitor acute lymphoblastic leukemia

Nature Genetics, 2019
Zhaohui Gu, M. Churchman, K. Roberts, Ian Moore, Xin Zhou, J. Nakitandwe, Kohei Hagiwara, Stéphane Pelletier, S. Gingras, H. Berns, D. Payne-Turner, Ashley D. Hill, I. Iacobucci, Lei Shi, S. Pounds, Cheng Cheng, Deqing Pei, Chunxu Qu, S. Newman, M. Devidas, Yunfeng Dai, S. Reshmi, J. Gastier-Foster, E. Raetz, M. Borowitz, B. Wood, W. Carroll, P. Zweidler-McKay, K. Rabin, L. Mattano, K. Maloney, A. Rambaldi, O. Spinelli, J. Radich, M. Minden, J. Rowe, S. Luger, M. Litzow, M. Tallman, J. Racevskis, Yanming Zhang, R. Bhatia, J. Kohlschmidt, K. Mrózek, C. Bloomfield, W. Stock, S. Kornblau, H. Kantarjian, M. Konopleva, W. Evans, S. Jeha, C. Pui, Jun J. Yang, E. Paietta, J. Downing, M. Relling, Jinghui Zhang, M. Loh, S. Hunger, C. Mullighan   +59 more
semanticscholar   +1 more source

Mitochondria and Neuromast Tagging With Fluorescent Gallium‐Triapine Analogues: In Cellulo MP FLIM and Zebrafish Live Imaging

Advanced Science, EarlyView.
Fluorescent BODIPY‐conjugated thiosemicarbazone ligands and their Ga(III), In(III), and Fe(III) complexes, inspired by Triapine, are developed as theranostic agents. Multiphoton FLIM and confocal microscopy in cancer cells and zebrafish reveal real‐time uptake, mitochondrial localisation, and whilst spectroscopic assays indicated preserved complex ...
Megan J. Green, Michael W. Jones, Merissa Saleem, Haobo Ge, Melita Tvardauskaite, Julia Dudzic, Fernando Cortezon‐Tamarit, Rory L. Arrowsmith, Charareh Pourzand, Gabriele Kociock‐Kohn, Nicholas H. Rees, Jonathan R. Dilworth, Stephen Faulkner, Stanley W. Botchway, David Gurevich, Sofia I. Pascu   +15 more
wiley   +1 more source

Where do immunotherapies stand in management of acute leukemia in adults? [PDF]

Hematology Am Soc Hematol Educ Program
Boissel N.
europepmc   +1 more source

N4‐acetylcytidine in LncRNA Gm26917 Promotes Translation in Female Germline Stem Cells by Recruiting Ribosomal Protein mRNA via EEF1A1

Advanced Science, EarlyView.
This work establishes that ac4C modification on lncRNA Gm26917 governs its spatial interactions with Rpl10 mRNA, and RBP EEF1A1 mediates the interaction between Gm26917 and Rpl10. It elucidates a novel ac4C‐Gm26917‐EEF1A1‐Rpl10 axis in FGSC maintenance both in vitro and in vivo, and provides a potential molecular target for modulating germ cell ...
Xinyue Li, Xiaopeng Hu, Ji Wu
wiley   +1 more source

Dynamic feedback control of oncogenic tyrosine kinase signaling in acute leukemia. [PDF]

Sci Signal
Lee J, Sun R, Kume K, Robinson ME, Cheng Z, Cosgun KN, Ma N, Hurtz C, Geng H, Luger SM, Litzow MR, Paietta E, Chen J, Vaidehi N, Müschen M.   +14 more
europepmc   +1 more source

Identifying Cytokine Motif‐Containing, Immunomodulatory Bacterial Proteins in Human Gut Microbiome

Advanced Science, EarlyView.
By building and constructing HMM (Upper left, blue), the authors identify CMCPs in bacteria genomes and CRC related metagenomes and enriched CRC‐related CMCPs (Upper right, blue). They analyze sequence and structural similarity of hits (Lower left, green), test function with engineered EcN delivered to tumors in a mouse tumor model (Lower right, pink ...
Ziyu Wang, Siqi Guo, Jing Li, Qianqian Huang, Jing Ning, Binbin Xia, Xun Lv, Xiang Liu, Zeyu Gao, Jine Li, Longchao Liu, Moshi Song, Jun Wang   +12 more
wiley   +1 more source

Macrophage Extracellular Traps in Immunity and Cancer

Advanced Science, EarlyView.
As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li, Eugenie Nepovimova, Adam Grundel, Lukas Peter, Qinghua Wu, Kamil Kuca   +5 more
wiley   +1 more source