Results 211 to 220 of about 420,896 (315)

AP2M1 Amplification Orchestrates Notch‐Mediated Chemoresistance in Hematopoietic Stem Cells of Acute Myeloid Leukemia Patients

Advanced Science, EarlyView.
The precise regulation of AP2M1 is essential for normal hematopoiesis. Overexpression of AP2M1 negatively affects the clinical outcomes of AML patients. Upregulation of AP2M1 enhances stemness and chemoresistance in HSPC cells of AML. AP2M1 modulates NOTCH1 expression, enhancing the Notch1 signaling pathway.
Hansong Lee, Eun Kyoung Kim, Hee Young Ju, Chae Rin Lee, Soyul Ahn, Eun‐Sun Kim, Kyungjae Myung, Won Kyu Kim, Su‐Yeon Cho, Yujin Kwon, Dokyoung Kim, Yeuni Yu, Eun Jung Kwon, Hyomin Kim, Seong Ik Mun, Dong Min Lim, Kihun Kim, Hye Jin Heo, Seung Eun Baek, Sun Young Lee, Hyunsoo Cho, Eun Young Choi, Tae Sik Goh, Ninib Baryawno, Dongjun Lee, Ki Sun Jung, Keon Hee Yoo, Chang‐Kyu Oh, Yun Hak Kim   +28 more
wiley   +1 more source

Phlegmonous Gastritis as the First Presentation of Acute Leukemia: A Case Report. [PDF]

Cureus
Alkubaisi MA, Mohammed NK, Ibrahim IS, Rashid HI.   +3 more
europepmc   +1 more source

Combinations of drugs in the treatment of acute leukemias.

, 1965
Zubrod Cg
openalex  

Enhancing Anti‐Tumor Effects of Engineered Extracellular Vesicles via Endocytosis Route Switching and Interferon Response Suppression

Advanced Science, EarlyView.
CD19‐293‐EV can switch the CD19 endocytosis pathway from clathrin‐mediated endocytosis to aggregation‐dependent endocytosis, leading to lysosomal degradation of the CD19/EVs complex. Degradation of the EVs leads to impairment in the IFN response and enhancement in EV uptake by target cells, creating a potent feedback cycle.
Zixuan Huang, Chaoqun Lu, Yixin Wang, Huajian Xian, Yuling Zheng, Ting Kang, Rufang Xiang, Shufeng Xie, Minghui Wang, Zeyi Li, Xiaoli Xia, Yaoyifu Yu, Wenjie Zhang, Huijian Zheng, Renyao Pan, Dan Li, Chunjun Zhao, Han Liu   +17 more
wiley   +1 more source

Risk of early death after acute leukemia diagnosis among adolescents and young adults. [PDF]

JNCI Cancer Spectr
Berkman AM, Andersen CR, Puthenpura V, Short NJ, Merriman K, Swaminathan M, Cuglievan B, McCall D, DiNardo C, Nunez C, Jain N, Kadia T, Issa G, Gibson A, Garcia MB, Livingston JA, Parsons S, Hildebrandt MAT, Roth ME.   +18 more
europepmc   +1 more source

Repurposing of Chemokine Antagonists for Combined Phase‐Resolved Spinal Cord Injury Treatment

Advanced Science, EarlyView.
Spinal cord injury (SCI) in mammals is accompanied by a massive cytokine storm in cerebrospinal fluid, mainly driven by CXCL1, IL‐6, and CCL2‐5. Sub‐acute phase is mostly associated with IL‐2, IL‐7, CCL22, and CX3CL1, whereas TNFα and IL17α permanently persists in CNS even weeks following SCI.
Alexey A. Belogurov Jr., Georgii B. Telegin, Aleksandr S. Chernov, Anna A. Kudriaeva, Alexey N. Minakov, Maksim V. Rodionov, Vitaly A. Kazakov, Viktor A. Palikov, Yuri M. Poluektov, Rustam H. Ziganshin, Daria A. Orlova, Alena S. Evpak, Daniil A. Barsuk, Fedor A. Mesheryakov, Aldo Spallone, Dmitry S. Asyutin, Igor N. Pronin, Nikolay A. Konovalov, Dmitri Yu Usachev, Alexander G. Gabibov, Alexander N. Konovalov   +20 more
wiley   +1 more source

Acute leukemia with Burkitt's tumor cells: A study of six cases with special reference to lymphocyte surface markers

, 1975
Georges Flandrin, J C Brouet, MT Daniel, JL Preud'homme   +3 more
openalex   +1 more source

Assessment of Bone Mineral Density in Pediatric Patients With Acute Leukemia. [PDF]

Cureus
Thomas S, Mahapatra M, Seth T, Viveka J.
europepmc   +1 more source

Clinical Significance of Copper Chaperone for Superoxide Dismutase in Colorectal Cancer

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background Targeting Cu transport proteins is an innovative therapeutic approach for combating cancer. However, the mechanisms underlying the malignant potential of Cu transport proteins remain largely unknown. To address this issue, we focused on the oncogenic potential of copper chaperones for superoxide dismutase (CCS) in colorectal cancer (
Nobuo Takiguchi, Mamoru Uemura, Mao Osaki, Chikako Kusunoki, Masakatsu Paku, Mitsunobu Takeda, Yuki Sekido, Tsuyoshi Hata, Atsushi Hamabe, Takayuki Ogino, Norikatsu Miyoshi, Mitsuyoshi Tei, Yoshinori Kagawa, Hirofumi Yamamoto, Yuichiro Doki, Hidetoshi Eguchi   +15 more
wiley   +1 more source

Blastemia portrays a poor prognosis in acute leukemia patients with invasive pulmonary aspergillosis. [PDF]

J Infect
Cho SY, Wurster S, Jiang Y, Bazinet A, Hui Y, Lewis RE, Matsuo T, Albert N, Garcia-Manero G, Kontoyiannis DP.   +9 more
europepmc   +1 more source