Results 271 to 280 of about 420,896 (315)
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Classification of Acute Leukemia
Annals of Internal Medicine, 1977The classification of acute leukemia has almost invariably been based on the morphologic diagnosis into two broad categories: acute lymphocytic and acute myeloid leukemia. Despite the wide range of morphologic variation in both groups, strict criteria to define the subgroups have only recently been proposed.
C. Sultan +4 more
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Pediatric Clinics of North America, 1985
The authors review the advances of the last decade in bone marrow culture cytogenetics and immunology that have aided in understanding the pathophysiology of acute nonlymphocytic leukemia and they also discuss the major strides in treatment that have occurred.
Holcombe E. Grier, Howard J. Weinstein
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The authors review the advances of the last decade in bone marrow culture cytogenetics and immunology that have aided in understanding the pathophysiology of acute nonlymphocytic leukemia and they also discuss the major strides in treatment that have occurred.
Holcombe E. Grier, Howard J. Weinstein
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Annals of Internal Medicine, 1968
Excerpt I would rather learn from one bird how to sing than teach ten thousand stars how not to dance. e. e.
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Excerpt I would rather learn from one bird how to sing than teach ten thousand stars how not to dance. e. e.
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Pharmacogenomics of Acute Leukemia
Pharmacogenomics, 2007Pharmacogenomics provides knowledge regarding how genetic polymorphisms affect treatment responses. Such an approach is particularly needed in cancer therapy, as most chemotherapeutics drugs affect both tumor and normal cells, are ineffective in many patients and exhibit serious side effects. Leukemia exists in two different forms, myeloid and lymphoid.
Marc Ansari, Maja Krajinovic
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AJN, American Journal of Nursing, 1975
One of the most encouraging endeavors in pediatric oncology in recent years has been the development of treatment regimens for acute lymphoblastic leukemia. Remission in children with leukemia was first induced with aminopterin in 1948(1). Since then, other drugs have been used in numerous combinations.
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One of the most encouraging endeavors in pediatric oncology in recent years has been the development of treatment regimens for acute lymphoblastic leukemia. Remission in children with leukemia was first induced with aminopterin in 1948(1). Since then, other drugs have been used in numerous combinations.
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American Journal of Hematology, 1979
AbstractAcute promyelocytic leukemia (APL) is characterized by proliferation of morphologically abnormal promyelocytes and a severe bleeding diathesis. The abnormal promyelocyte is characterized by abundant, large granules, many of which are spindle‐shaped. Electron microscopic appearance of the granules closely resembles that of Auer rods.
Jerome E. Groopman, Leonard Ellman
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AbstractAcute promyelocytic leukemia (APL) is characterized by proliferation of morphologically abnormal promyelocytes and a severe bleeding diathesis. The abnormal promyelocyte is characterized by abundant, large granules, many of which are spindle‐shaped. Electron microscopic appearance of the granules closely resembles that of Auer rods.
Jerome E. Groopman, Leonard Ellman
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Journal of Pediatric Hematology/Oncology, 1995
Significant advances have occurred in the diagnosis, treatment, and long-term outcome of patients with acute promyelocytic leukemia (APL). The purpose of this review is to describe the molecular genetics of this disease, the use of all-trans retinoic acid (ATRA) in clinical trials of APL, and the clinical and basic research questions for future ...
David Eilender +6 more
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Significant advances have occurred in the diagnosis, treatment, and long-term outcome of patients with acute promyelocytic leukemia (APL). The purpose of this review is to describe the molecular genetics of this disease, the use of all-trans retinoic acid (ATRA) in clinical trials of APL, and the clinical and basic research questions for future ...
David Eilender +6 more
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American Journal of Ophthalmology, 1979
A 71-year-old woman had a history of recent weight loss and bilateral decreased visual acuity, bilateral serous detachment, and mental depression. Fluorescein angiograms showed a myriad of retinal pigment epithelial leakage points. Despite extensive evaluation, the cause of her weight loss and ocular process remained uncertain until her death, when ...
Marilyn C. Kincaid +2 more
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A 71-year-old woman had a history of recent weight loss and bilateral decreased visual acuity, bilateral serous detachment, and mental depression. Fluorescein angiograms showed a myriad of retinal pigment epithelial leakage points. Despite extensive evaluation, the cause of her weight loss and ocular process remained uncertain until her death, when ...
Marilyn C. Kincaid +2 more
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European Journal of Haematology, 2001
Abstract: Acute basophilic leukemia has recently been included into a revised classification of acute leukemias proposed by the WHO panel. Due to the rarity of the disease, consistent diagnostic criteria are lacking. We report on two cases of acute basophilic leukemia that occurred in our department during the last 10 yr.
Manuel Aivado +5 more
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Abstract: Acute basophilic leukemia has recently been included into a revised classification of acute leukemias proposed by the WHO panel. Due to the rarity of the disease, consistent diagnostic criteria are lacking. We report on two cases of acute basophilic leukemia that occurred in our department during the last 10 yr.
Manuel Aivado +5 more
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Archives of Pediatrics & Adolescent Medicine, 1979
Acute leukemia in children and adults is still a serious disease, but progress made during the past decade has been encouraging. Physicians-in-training, nonspecialist practitioners, and paramedical personnel should be aware of advances in the field to make the best therapy available to the infrequently encountered patient.
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Acute leukemia in children and adults is still a serious disease, but progress made during the past decade has been encouraging. Physicians-in-training, nonspecialist practitioners, and paramedical personnel should be aware of advances in the field to make the best therapy available to the infrequently encountered patient.
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