Results 21 to 30 of about 3,163,010 (367)
Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia.
BACKGROUND Many mutations that contribute to the pathogenesis of acute myeloid leukemia (AML) are undefined. The relationships between patterns of mutations and epigenetic phenotypes are not yet clear.
T. Ley+99 more
semanticscholar +1 more source
Deferasirox is an oral iron‐chelating agent having possible antileukemia and immune modulatory effects. Few reports have evaluated deferasirox in the setting of allogeneic hematopoietic stem cell transplantation (allo‐HSCT). We investigated the impact of
Byung‐Sik Cho+14 more
doaj +1 more source
There are situations where non-first-degree (NFD) related donors have to be considered as alternatives to first-degree (FD) related donors for haploidentical hematopoietic cell transplantation (HAPLO).
Yishan Ye+15 more
doaj +1 more source
Acute Lymphoblastic Leukemia Detection Using Hypercomplex-Valued Convolutional Neural Networks [PDF]
This paper features convolutional neural networks defined on hypercomplex algebras applied to classify lymphocytes in blood smear digital microscopic images. Such classification is helpful for the diagnosis of acute lymphoblast leukemia (ALL), a type of blood cancer.
arxiv +1 more source
Long‐Term Follow‐up of CD19 CAR Therapy in Acute Lymphoblastic Leukemia
Background CD19‐specific chimeric antigen receptor (CAR) T cells induce high rates of initial response among patients with relapsed B‐cell acute lymphoblastic leukemia (ALL) and long‐term remissions in a subgroup of patients. Methods We conducted a phase
Jae H. Park+14 more
semanticscholar +1 more source
Automated Detection of Acute Leukemia using K-mean Clustering Algorithm [PDF]
Leukemia is a hematologic cancer which develops in blood tissue and triggers rapid production of immature and abnormal shaped white blood cells. Based on statistics it is found that the leukemia is one of the leading causes of death in men and women alike.
arxiv +1 more source
A survey on automated detection and classification of acute leukemia and WBCs in microscopic blood cells [PDF]
Leukemia (blood cancer) is an unusual spread of White Blood Cells or Leukocytes (WBCs) in the bone marrow and blood. Pathologists can diagnose leukemia by looking at a person's blood sample under a microscope. They identify and categorize leukemia by counting various blood cells and morphological features.
arxiv
Midostaurin plus Chemotherapy for Acute Myeloid Leukemia with a FLT3 Mutation
Background Patients with acute myeloid leukemia (AML) and a FLT3 mutation have poor outcomes. We conducted a phase 3 trial to determine whether the addition of midostaurin — an oral multitargeted kinase inhibitor that is active in patients with a FLT3 ...
R. Stone+28 more
semanticscholar +1 more source
Deletion 5q or monosomy 5 (-5/5q-) in acute myeloid leukemia (AML) is a common high-risk feature that is referred to allogeneic stem cell transplantation.
Xavier Poiré+15 more
doaj +1 more source