Results 21 to 30 of about 3,163,010 (367)

Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia.

open access: yesNew England Journal of Medicine, 2013
BACKGROUND Many mutations that contribute to the pathogenesis of acute myeloid leukemia (AML) are undefined. The relationships between patterns of mutations and epigenetic phenotypes are not yet clear.
T. Ley   +99 more
semanticscholar   +1 more source

Improved survival outcomes and restoration of graft‐vs‐leukemia effect by deferasirox after allogeneic stem cell transplantation in acute myeloid leukemia

open access: yesCancer Medicine, 2019
Deferasirox is an oral iron‐chelating agent having possible antileukemia and immune modulatory effects. Few reports have evaluated deferasirox in the setting of allogeneic hematopoietic stem cell transplantation (allo‐HSCT). We investigated the impact of
Byung‐Sik Cho   +14 more
doaj   +1 more source

Similar outcomes following non-first-degree and first-degree related donor haploidentical hematopoietic cell transplantation for acute leukemia patients in complete remission: a study from the Global Committee and the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation

open access: yesJournal of Hematology & Oncology, 2023
There are situations where non-first-degree (NFD) related donors have to be considered as alternatives to first-degree (FD) related donors for haploidentical hematopoietic cell transplantation (HAPLO).
Yishan Ye   +15 more
doaj   +1 more source

Acute Lymphoblastic Leukemia Detection Using Hypercomplex-Valued Convolutional Neural Networks [PDF]

open access: yes2022 International Joint Conference on Neural Networks (IJCNN), 2022
This paper features convolutional neural networks defined on hypercomplex algebras applied to classify lymphocytes in blood smear digital microscopic images. Such classification is helpful for the diagnosis of acute lymphoblast leukemia (ALL), a type of blood cancer.
arxiv   +1 more source

Long‐Term Follow‐up of CD19 CAR Therapy in Acute Lymphoblastic Leukemia

open access: yesNew England Journal of Medicine, 2018
Background CD19‐specific chimeric antigen receptor (CAR) T cells induce high rates of initial response among patients with relapsed B‐cell acute lymphoblastic leukemia (ALL) and long‐term remissions in a subgroup of patients. Methods We conducted a phase
Jae H. Park   +14 more
semanticscholar   +1 more source

Automated Detection of Acute Leukemia using K-mean Clustering Algorithm [PDF]

open access: yesAdvances in Intelligent Systems and Computing, vol 554. Springer, 2018, 2018
Leukemia is a hematologic cancer which develops in blood tissue and triggers rapid production of immature and abnormal shaped white blood cells. Based on statistics it is found that the leukemia is one of the leading causes of death in men and women alike.
arxiv   +1 more source

A survey on automated detection and classification of acute leukemia and WBCs in microscopic blood cells [PDF]

open access: yesarXiv, 2023
Leukemia (blood cancer) is an unusual spread of White Blood Cells or Leukocytes (WBCs) in the bone marrow and blood. Pathologists can diagnose leukemia by looking at a person's blood sample under a microscope. They identify and categorize leukemia by counting various blood cells and morphological features.
arxiv  

Acute Leukemia [PDF]

open access: yesThe Boston Medical and Surgical Journal, 1894
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openaire   +2 more sources

Midostaurin plus Chemotherapy for Acute Myeloid Leukemia with a FLT3 Mutation

open access: yesNew England Journal of Medicine, 2017
Background Patients with acute myeloid leukemia (AML) and a FLT3 mutation have poor outcomes. We conducted a phase 3 trial to determine whether the addition of midostaurin — an oral multitargeted kinase inhibitor that is active in patients with a FLT3 ...
R. Stone   +28 more
semanticscholar   +1 more source

Allogeneic stem cell transplantation using HLA-matched donors for acute myeloid leukemia with deletion 5q or monosomy 5: a study from the Acute Leukemia Working Party of the EBMT

open access: yesHaematologica, 2020
Deletion 5q or monosomy 5 (-5/5q-) in acute myeloid leukemia (AML) is a common high-risk feature that is referred to allogeneic stem cell transplantation.
Xavier Poiré   +15 more
doaj   +1 more source

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