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Out of various etiology involved in liver pathology viral and metabolic causes are important in children. Hypoxic and ischemic liver injury are commonly seen in PICU.
Kundan Mittal+2 more
doaj +4 more sources
Acute liver failure is an uncommon disease presenting with abrupt failure of liver synthetic and detoxification functions on account of widespread damage to hepatocytes and is associated with high mortality.
Vikash Prakash
doaj +3 more sources
Severe hepatitis A infection is an infrequent but well-recognized cause of acute liver failure that can now be effectively prevented with vaccination against hepatitis A virus. Bromfenac and troglitazone hepatotoxicity as well as various herbal remedies are some of the newly identified causes of acute liver failure.
John O’Grady
+7 more sources
Acute liver failure is a rare syndrome and is primarily caused by paracetamol toxicity in developed nations. Survival for patients with acute liver failure has steadily improved over the last few decades from approximately 20% to greater than 60%. This marked improvement in survival has been due to a combination of improvements in medical practice and ...
Sandro, Vento, Francesca, Cainelli
semanticscholar +9 more sources
Liver Transplantation for Acute Liver Failure due to Mushroom Poisoning [PDF]
Background/Aims: Liver transplantation is a life-saving approach in some cases of mushroom poisoning, which is one of the important causes of acute liver failure. However, debate continues regarding the timing of liver transplantation.
Hayri Canbaz+4 more
doaj +2 more sources
Acute liver failure is a rare but often catastrophic illness affecting the liver and multiple organ systems. Patients with acute liver failure require a multidisciplinary approach for adequate management.
Murali Pathikonda, Santiago J. Munoz, MD
doaj +5 more sources
Pediatric acute liver failure (PALF) has recently become a subject of great interest when multiple clusters of non-A to non-E severe acute hepatitis in otherwise healthy young children with a median age of 2 years were reported around the world [...]
Claudia Mandato, Pietro Vajro
doaj +3 more sources
Systematic review of the global epidemiology of viral-induced acute liver failure
Objectives The aetiology and burden of viral-induced acute liver failure remains unclear globally. It is important to understand the epidemiology of viral-induced ALF to plan for clinical case management and case prevention.Participants This systematic ...
Rudzani Muloiwa+8 more
doaj +2 more sources
Progress in mesenchymal stem cell–based therapy for acute liver failure
Acute liver failure is a life-threatening clinical syndrome characterized by rapid development of hepatocellular necrosis leading to high mortality and resource costs. Numerous treatment strategies for acute liver failure simply prevent complications and
Yong-Hong Wang+4 more
doaj +2 more sources
Acute Liver Failure Guidelines
Acute liver failure (ALF) is a rare, acute, potentially reversible condition resulting in severe liver impairment and rapid clinical deterioration in patients without preexisting liver disease.
Alexandra Shingina+7 more
semanticscholar +1 more source