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Acute Liver Failure [PDF]

open access: yesSeminars in Respiratory and Critical Care Medicine, 1993
Acute liver failure (ALF) (sometimes referred to as fulminant hepatic failure) is a clinical syndrome from a variety of causes resulting from rapid loss in hepatocyte function, typically associated with coagulopathy and encephalopathy in a patient without preexisting liver disease or cirrhosis. Cerebral edema is a cardinal feature and may produce uncal
William M Lee
openaire   +6 more sources

Acute-on-chronic liver failure in cirrhosis [PDF]

open access: yesNature Reviews Disease Primers, 2016
The definition of acute-on-chronic liver failure (ACLF) remains contested. In Europe and North America, the term is generally applied according to the European Association for the Study of the Liver-Chronic Liver Failure (EASL-CLIF) Consortium guidelines,
Arroyo, V   +9 more
core   +2 more sources

Predicting outcome on admission and post-admission for acetaminophen-induced acute liver failure using classification and regression tree models. [PDF]

open access: yesPLoS ONE, 2015
Assessing prognosis for acetaminophen-induced acute liver failure (APAP-ALF) patients often presents significant challenges. King's College (KCC) has been validated on hospital admission, but little has been published on later phases of illness. We aimed
Jaime Lynn Speiser   +3 more
doaj   +1 more source

Analysis of serum inflammatory mediators identifies unique dynamic networks associated with death and spontaneous survival in pediatric acute liver failure. [PDF]

open access: yesPLoS ONE, 2013
Tools to predict death or spontaneous survival are necessary to inform liver transplantation (LTx) decisions in pediatric acute liver failure (PALF), but such tools are not available.
Nabil Azhar   +6 more
doaj   +1 more source

Detection of Ophthalmic Acid in Serum from Acetaminophen-Induced Acute Liver Failure Patients Is More Frequent in Non-Survivors. [PDF]

open access: yesPLoS ONE, 2015
Acetaminophen (APAP) hepatotoxicity is related to the formation of N-acetyl-p-benzoquinone imine (NAPQI), which is detoxified through conjugation with reduced glutathione (GSH).
Gurnit Kaur   +6 more
doaj   +1 more source

Acute liver failure [PDF]

open access: yesPostgraduate Medical Journal, 1997
Abstract Acute liver failure is a complex multisystemic illness that evolves quickly after a catastrophic insult to the liver leading to the development of encephalopathy. The underlying aetiology and the pace of progression strongly influence the clinical course.
openaire   +5 more sources

Acute Liver Failure [PDF]

open access: yesClinical Medicine, 2015
Acute liver failure is a rare but potentially fatal disease. Adult definition of fulminant hepatic failure, which includes the development of hepatic necrosis and encephalopathy within 8 weeks of onset of liver disease does not apply to acute liver failure in children particularly if secondary to autoimmune or metabolic liver disease.
Laura, Blackmore, William, Bernal
openaire   +4 more sources

Acute Liver Failure Secondary to Hepatic Infiltration of Malignant Melanoma [PDF]

open access: yesClinical Endoscopy, 2022
Acute liver failure due to malignant melanoma is uncommon. We presents a case of acute liver failure secondary to hepatic infiltration of a malignant melanoma.
Yujin Lee   +7 more
doaj   +1 more source

Pediatric acute liver failure: An experience of a pediatric intensive care unit from resource limited settings

open access: yesFrontiers in Pediatrics, 2022
IntroductionPediatric acute liver failure is a rare and serious disease. Though liver transplantation is considered as the established treatment option for patients who are unlikely to recover with medical management, however, with the advancement of ...
Puja Amatya   +6 more
doaj   +1 more source

Early Acute Liver Failure in Severe Acute Hepatitis B [PDF]

open access: yes, 2002
Early acute liver failure is defined by the presence of a drop below 50% of the normal prothrombine ratio, jaundice, and clotting factors of less than 50% in any patient with acute liver disease.
Siregar, G. A. (Gontar)
core   +1 more source

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