Results 11 to 20 of about 653,174 (341)
Predicting outcome on admission and post-admission for acetaminophen-induced acute liver failure using classification and regression tree models. [PDF]
PLoS ONE, 2015 Assessing prognosis for acetaminophen-induced acute liver failure (APAP-ALF) patients often presents significant challenges. King's College (KCC) has been validated on hospital admission, but little has been published on later phases of illness. We aimed
Jaime Lynn Speiser +3 more
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Analysis of serum inflammatory mediators identifies unique dynamic networks associated with death and spontaneous survival in pediatric acute liver failure. [PDF]
PLoS ONE, 2013 Tools to predict death or spontaneous survival are necessary to inform liver transplantation (LTx) decisions in pediatric acute liver failure (PALF), but such tools are not available.
Nabil Azhar +6 more
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Detection of Ophthalmic Acid in Serum from Acetaminophen-Induced Acute Liver Failure Patients Is More Frequent in Non-Survivors. [PDF]
PLoS ONE, 2015 Acetaminophen (APAP) hepatotoxicity is related to the formation of N-acetyl-p-benzoquinone imine (NAPQI), which is detoxified through conjugation with reduced glutathione (GSH).
Gurnit Kaur +6 more
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Postgraduate Medical Journal, 1997 Abstract Acute liver failure is a complex multisystemic illness that evolves quickly after a catastrophic insult to the liver leading to the development of encephalopathy. The underlying aetiology and the pace of progression strongly influence the clinical course.
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Clinical Medicine, 2015 Acute liver failure is a rare but potentially fatal disease. Adult definition of fulminant hepatic failure, which includes the development of hepatic necrosis and encephalopathy within 8 weeks of onset of liver disease does not apply to acute liver failure in children particularly if secondary to autoimmune or metabolic liver disease.
Laura, Blackmore, William, Bernal
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Acute Liver Failure Secondary to Hepatic Infiltration of Malignant Melanoma [PDF]
Clinical Endoscopy, 2022 Acute liver failure due to malignant melanoma is uncommon. We presents a case of acute liver failure secondary to hepatic infiltration of a malignant melanoma.
Yujin Lee +7 more
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Frontiers in Pediatrics, 2022 IntroductionPediatric acute liver failure is a rare and serious disease. Though liver transplantation is considered as the established treatment option for patients who are unlikely to recover with medical management, however, with the advancement of ...
Puja Amatya +6 more
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Seminars in Respiratory and Critical Care Medicine, 1993 Acute liver failure (ALF) (sometimes referred to as fulminant hepatic failure) is a clinical syndrome from a variety of causes resulting from rapid loss in hepatocyte function, typically associated with coagulopathy and encephalopathy in a patient without preexisting liver disease or cirrhosis. Cerebral edema is a cardinal feature and may produce uncal
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Annals of Intensive Care, 2017 Background Acetaminophen (APAP)-induced acute liver failure (ALF) is associated with significant mortality due to intracranial hypertension (ICH), a result of cerebral edema (CE) and astrocyte swelling.
Constantine J. Karvellas +5 more
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Brain edema in acute liver failure and chronic liver disease: Similarities and differences [PDF]
, 2013 Hepatic encephalopathy (HE) is a complex neuropsychiatric syndrome that typically develops as a result of acute liver failure or chronic liver disease. Brain edema is a common feature associated with HE. In acute liver failure, brain edema contributes to
Bosoi, Cristina R., Rose, Christopher
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