Results 51 to 60 of about 1,006,426 (373)

Decreased glutamate transporter (GLT-1) expression in frontal cortex of rats with acute liver failure [PDF]

, 1997
It has been suggested that reduced astrocytic uptake of neuronally released glutamate contributes to the pathogenesis of hepatic encephalopathy in acute liver failure.
Butterworth, Roger, Knecht, K., Michalak, Adrianna, Rose, Christopher, Rothstein, Jane D.   +4 more
core   +1 more source

Current approach to diagnosis and treatment for liver failure (literature review)

Acta Biomedica Scientifica, 2016
Currently, the world is marked rise in the number of patients with liver disease. Approximately 100,000 patients hepatitis complicated by acute liver failure, with mortality in this disease reaches 70-90 % despite the use of modern methods of treatment ...
A. N. Plekhanov, A. I. Tovarshinov
doaj   +1 more source

Imatinib-induced fulminant liver failure in chronic myeloid leukemia: role of liver transplant and second-generation tyrosine kinase inhibitors: a case report

Journal of Medical Case Reports, 2018
Background There is a worldwide problem of acute liver failure and mortality associated with remaining on the waiting for a liver transplant. In this study, we highlight results published in recent years by leading transplant centers in evaluating ...
Lucas Souto Nacif, Daniel R. Waisberg, Rafael Soares Pinheiro, Fabiana Roberto Lima, Vinicius Rocha-Santos, Wellington Andraus, Luiz Carneiro D’Albuquerque   +6 more
doaj   +1 more source

Pharmacokinetics and efficacy of oral versus intravenous mixed-micellar phylloquinone (vitamin K-1) in severe acute liver disease [PDF]

, 2005
Background/Aims: In patients with severe acute liver dysfunction, i.v. phylloquinone (vitamin K-1) may be given to exclude vitamin K deficiency, rather than impaired hepatic synthesis of coagulation factors alone, as the cause of the coagulopathy ...
Fitt, S, Pereira, SP, Rowbotham, D, Shearer, MJ, Wendon, J, Williams, R   +5 more
core   +1 more source

Plasma Glutamine Concentrations in Liver Failure. [PDF]

PLoS ONE, 2016
Higher than normal plasma glutamine concentration at admission to an intensive care unit is associated with an unfavorable outcome. Very high plasma glutamine levels are sometimes seen in both acute and chronic liver failure.
Gunnel Helling, Staffan Wahlin, Marie Smedberg, Linn Pettersson, Inga Tjäder, Åke Norberg, Olav Rooyackers, Jan Wernerman   +7 more
doaj   +1 more source

Soyasaponin II protects against acute liver failure through diminishing YB-1 phosphorylation and Nlrp3-inflammasome priming in mice

Theranostics, 2020
Acute liver failure is characterized by the rapid development of liver dysfunction and remarkably high mortality. Accumulating evidence suggests that soyasaponin possesses potential anti-inflammatory activities.
Fangzhao Wang, Shenhai Gong, Teng Wang, Lei Li, Hai-hua Luo, Junhao Wang, Chenyang Huang, Hongwei Zhou, Guiming Chen, Zhanguo Liu, Qifan Zhang, Yong Jiang, Peng Chen   +12 more
semanticscholar   +1 more source

MARS therapy, the bridging to liver retransplantation-Three cases from the Hungarian liver transplant program [PDF]

, 2014
Besides orthotopic liver transplantation (OLT) there is no long-term and effective replacement therapy for severe liver failure. Artificial extracorporeal liver supply devices are able to reduce blood toxin levels, but do not replace any synthetic ...
Bacher A., Ding Y.T., Doros A., Evenepoel P., Gaspari R., Hessel F.P., Kantola T., Kantola T., Karvellas C.J., Liu Y.H., Nemes B., Nemes B., Novelli G., Novelli G., Rademacher S., Rifai K., Schiff E.R., Schuller J., Tan H.K., Wang M.M., Wong F.   +20 more
core   +2 more sources

Macrophage Activation Markers, CD163 and CD206, in Acute-on-Chronic Liver Failure

Cells, 2020
Macrophages facilitate essential homeostatic functions e.g., endocytosis, phagocytosis, and signaling during inflammation, and express a variety of scavenger receptors including CD163 and CD206, which are upregulated in response to inflammation.
M. Nielsen, Rasmus Hvidbjerg Gantzel, J. Clària, J. Trebicka, H. Møller, H. Grønbæk   +5 more
semanticscholar   +1 more source

Circulating microRNAs: promising candidates serving as novel biomarkers of acute hepatitis [PDF]

, 2012
Acute liver failure as life threatening condition comprises a difficult diagnostic situation to evaluate potential outcomes and therapeutic options. Thus, prognostic indicators are urgently needed for evaluation of progression of liver injury, clinical ...
Ali Canbay, Hans Peter Dienes, Jan-Peter Sowa, Margarete Odenthal, Martin Schlattjan, Natalia Elfimova   +5 more
core   +2 more sources

Guidelines for the Management of Adult Acute and Acute-on-Chronic Liver Failure in the ICU: Cardiovascular, Endocrine, Hematologic, Pulmonary, and Renal Considerations

Critical Care Medicine, 2020
Supplemental Digital Content is available in the text. Objectives: To develop evidence-based recommendations for clinicians caring for adults with acute or acute on chronic liver failure in the ICU.
R. Nanchal, R. Subramanian, C. Karvellas, S. Hollenberg, William J. Peppard, K. Singbartl, J. Truwit, A. AL-Khafaji, Alley Killian, Mustafa Alquraini, K. Alshammari, F. Alshamsi, E. Belley‐Cote, R. Cartin-Ceba, J. Dionne, D. Galusca, David T. Huang, R. Hyzy, Mats L Junek, P. Kandiah, G. Kumar, R. Morgan, P. Morris, J. Olson, R. Sieracki, R. Steadman, B. Taylor, W. Alhazzani   +27 more
semanticscholar   +1 more source