Results 1 to 10 of about 563,443 (191)

Febuxostat-induced acute liver injury [PDF]

Hepatology, 2016
Febuxostat is a unique xanthine oxidase inhibitor that was approved for the prevention of gout in the United States in 2009. Unlike allopurinol, febuxostat is not a nucleoside analogue and has a higher specificity for xanthine oxidase. Although this drug
Matt Bohm, Naga Chalasani, null null, Raj Vuppalanchi   +3 more
core   +5 more sources

Disulfiram-Induced Acute Liver Injury [PDF]

Case Reports in Hepatology, 2020
Disulfiram is a drug used to treat alcohol dependence since many years. It interferes with the metabolism of alcohol, may be associated with neurological and dermatological symptoms, and can be hepatotoxic.
Lucas Ramer, Matthieu Tihy, Nicolas Goossens, Jean-Louis Frossard, Laura Rubbia-Brandt, Laurent Spahr   +5 more
doaj   +5 more sources

Amiodarone-Induced Acute Liver Injury [PDF]

Case Reports in Gastroenterology, 2020
Amiodarone is a lipophilic structure with a half-life of 25–100 days. Long-term oral amiodarone is associated with photosensitivity, thyroid dysfunction, and pulmonary and hepatic toxicity.
Rajesh Essrani, Shehriyar Mehershahi, Rajesh Kumar Essrani, Shri Jai Kirshan Ravi, Sajeer Bhura, Anuraj Sudhakaran, Muhammad Hossain, Asif Mehmood   +7 more
doaj   +3 more sources

Acute alcohol-induced liver injury [PDF]

Frontiers in Physiology, 2012
Alcohol consumption is customary in most cultures and alcohol abuse is common worldwide. For example, more than 50% of Americans consume alcohol, with an estimated 23.1% of Americans participating in heavy and/or binge drinking at least once a month. A
Gavin Edward Arteel
doaj   +3 more sources

Tirzepatide-related acute liver injury

European Journal of Case Reports in Internal Medicine
Tirzepatide, a modified protein containing 39 amino acids, acts as a dual agonist at the gastric inhibitory polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptors, showing great promise in weight-loss treatment.
Irrum Abdullah, Husam El-Ghousain, Meshaan Alenezi   +2 more
doaj   +3 more sources

LncRNA-Airn alleviates acute liver injury by inhibiting hepatocyte apoptosis via the NF-κB signaling pathway

Acta Biochimica et Biophysica Sinica, 2022
Acute liver injury is a common and serious syndrome caused by multiple factors and unclear pathogenesis. If the injury persists, liver injury can lead to cirrhosis and liver failure and ultimately results in the development of liver cancer.
Shao Shuai, Zhang Yu, Zhou Feng, Meng Xiaoxiang, Yu Zhenjun, Li Guantong, Zheng Lina, Zhang Kun, Li Yuhan, Guo Beichen, Liu Qi, Zhang Mengxia, Du Xiaoxiao, Hong Wei, Han Tao   +14 more
doaj   +1 more source

Gut Microbiota and Chemical-Induced Acute Liver Injury

Frontiers in Physiology, 2021
Background: Drug overdose or chemical exposures are the main causes of acute liver injury (ALI). Severe liver injury can develop into liver failure that is an important cause of liver-related mortality in intensive care units in most countries ...
Tao Chen, Tao Chen, Rui Li, Peng Chen
doaj   +1 more source

Determination of HMGB1 in hepatitis B virus-related acute-on-chronic liver failure patients with acute kidney injury: Early prediction and prognostic implications

Frontiers in Pharmacology, 2023
Background: Acute kidney injury (AKI) is a frequent complication in patients with hepatitis B virus-related acute-on-chronic liver failure (HBV-ACLF) and is associated with high rates of mortality. We aimed to estimate serum high mobility group protein 1
Yu Liu, Yu Liu, Wei Yuan, Miao Fang, Hongying Guo, Xin Zhang, Xue Mei, Yuyi Zhang, Longshan Ji, Yating Gao, Jiefei Wang, Zhiping Qian, Man Li, Yueqiu Gao, Yueqiu Gao   +14 more
doaj   +1 more source

Circulating microRNAs Reveal Time Course of Organ Injury in a Porcine Model of Acetaminophen-Induced Acute Liver Failure [PDF]

, 2015
Acute liver failure is a rare but catastrophic condition which can progress rapidly to multi-organ failure. Studies investigating the onset of individual organ injury such as the liver, kidneys and brain during the evolution of acute liver failure, are ...
A O'Riordan, A Turchinovich, AB Imaeda, AM Larson, AM Reddy, B Ekser, Carolina Palacios Jimenez, CD Williams, CL Andersen, D Mladinov, Diego Calvisi, DJ Antoine, E Cholongitas, F Martino, Fausto Andreola, G Szabo, Hatim Alibhai, HT Zhu, J Hellemans, J Vandesompele, JG O'Grady, JK Moore, K John, K Purins, K Wang, Karla C. L. Lee, KC Lee, Lewis PJ Starkey, Luisa A. Baker, M Karali, M Lagos-Quintana, M Weiland, ML Bajt, MR McGill, MW Pfaffl, N Silver, Nathan A. Davies, O Timoneda, O Timoneda, OF Laterza, P Gilje, P Landgraf, Pamela J. Leckie, PS Mitchell, Q Ge, R Bellomo, Rajeshwar P. Mookerjee, Rajiv Jalan, RL Mehta, RT Stravitz, S Bala, T Kawai, W Bernal, WE Hoffman, WM Lee, X Chen, Y Sun, Y Wang, Y Zhang, Yu-Mei Chang, YW Kong   +60 more
core   +9 more sources

Prevalence of Acute Kidney Injury in Patients with Liver Cirrhosis

Journal of Nepal Medical Association, 2020
Introduction: Acute kidney injury is a common and life-threatening event in patients with liver cirrhosis occurring in approximately 20-50% of hospitalized patients of liver cirrhosis. Pre-renal acute kidney injury, the hepatorenal syndrome type of acute
Pukar Thapa, Sudhamshu KC, Achyut Bikram Hamal, Dilip Sharma, Sandip Khadka, Niyanta Karki, Bikash Jaishi, Pratap Sagar Tiwari, Anshu Vaidya, Binod Karki   +9 more
doaj   +1 more source