ABSTRACT Liver fibrosis is a serious yet reversible intermediate stage in the progression of liver disease, which can ultimately advance to cirrhosis and hepatocellular carcinoma. Targeted and selective inhibition of activated hepatic stellate cells (aHSCs) has emerged as a promising therapeutic strategy for the treatment of liver fibrosis.
Shutong Liu +8 more
wiley +1 more source
Integrating Network Pharmacology, Molecular Docking, and Experimental Validation: Andrographolide Attenuates Acute Liver Injury via the NLRP3/Caspase-1/GSDMD-Mediated Pyroptosis Pathway. [PDF]
Zhang Y, Liu S, Liang X, Yin L, He C.
europepmc +1 more source
Deployable 3D‐Printed Vascular Stent with Surface‐Catalysed Endogenous Nitric Oxide Generation
A deployable 3D‐printed vascular stent was fabricated with surface‐catalyzed endogenous nitric oxide generation, representing a promising new direction for stent development. The stent can be remotely controlled by magnetic force in its compressed state and fully deployed at the target site using an untethered heat source, potentially eliminating the ...
Kun Zhou +8 more
wiley +1 more source
Alpinetin pretreatment prevents lipopolysaccharide/D-galactosamine-induced acute liver injury in mice by inhibiting ferroptosis via the Nrf2/SLC7A11/GPX4 pathway. [PDF]
Liu Y, Zhao J, Cong W, Liu T, Sha K.
europepmc +1 more source
Mechanisms of sepsis-induced acute liver injury: a comprehensive review. [PDF]
Guo Y, Guo W, Chen H, Sun J, Yin Y.
europepmc +1 more source
SENP3 protects hepatocyte from pyroptosis during acute liver injury through deSUMOylation of HNRNPL. [PDF]
Xiong X +9 more
europepmc +1 more source
<i>Lacticaseibacillus paracasei</i> FJG2337 mitigate acute liver injury-related inflammatory responses, gut microbiota and liver metabolism in mice. [PDF]
He S, Yang Y, Guo W, Ou R, Lv X, Chen Y.
europepmc +1 more source
Tissue-engineered liver using 3D-printed silk fibroin scaffolds loaded with stem cells for the treatment of acute liver injury. [PDF]
Shi X +14 more
europepmc +1 more source
Sevoflurane-Associated Acute Liver Injury in Renal Transplantation and Review of Literature. [PDF]
Gani I, Moin N, Fallah J, Mirza A.
europepmc +1 more source

