Results 91 to 100 of about 542,420 (309)

Tofacitinib reduces acute lung injury and improves survival in a rat model of sepsis by inhibiting the JAK-STAT/NF-κB pathway

Journal of Inflammation, 2023
Acute lung injury is a major cause of death in sepsis. Tofacitinib (TOFA), a JAK inhibitor, has anti-inflammatory activity in autoimmune diseases, but its role in acute lung injury in sepsis remains unclear.
Xinxin Zhang, Xingsheng Wang, Li Sun, Guangsheng Gao, Yun Li   +4 more
doaj   +1 more source

The Role of rescue therapies in the treatment of severe ARDS [PDF]

, 2018
ARDS is characterized by a non-cardiogenic pulmonary edema with bilateral chest radiograph opacities and hypoxemia refractory to oxygen therapy. It is a common cause of admission to the ICU due to hypoxemic respiratory failure requiring mechanical ...
Alessandri, F, Pugliese, F, Ranieri, M.
core   +1 more source

Hospital Readmission After Traumatic Brain Injury Hospitalization in Community‐Dwelling Older Adults

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the risk of hospital readmission after an index hospitalization for TBI in older adults. Methods Using data from the Atherosclerosis Risk in Communities (ARIC) study, we used propensity score matching of individuals with an index TBI‐related hospitalization to individuals with (1) non‐TBI hospitalizations (primary analysis)
Rachel Thomas, Connor A. Law, Joan A. Casey, Thomas Mosley, Rebecca F. Gottesman, Ramon Diaz‐Arrastia, Holly Elser, Andrea L. C. Schneider   +7 more
wiley   +1 more source

A cluster randomized trial on inspiratory effort-targeted pressure support adjustment strategy in patients undergoing assisted mechanical ventilation: protocol for the IT-PSV study

Frontiers in Medicine
BackgroundPressure support ventilation (PSV) is one of the most frequently used ventilator modes in the intensive care unit (ICU). The successful implementation of PSV depends on matching the patient’s inspiratory effort with the ventilator support.
Wen-Yi Lu, Wen-Yi Lu, Ming-Yue Miao, Ran Gao, Yan-Lin Yang, Linlin Zhang, Li Weng, Feng-Xue Zhu, Lei Liu, Jian-Xin Zhou   +9 more
doaj   +1 more source

Biomarkers in solid organ transplantation: establishing personalized transplantation medicine. [PDF]

, 2011
Technological advances in molecular and in silico research have enabled significant progress towards personalized transplantation medicine. It is now possible to conduct comprehensive biomarker development studies of transplant organ pathologies ...
Khatri, Purvesh, Roedder, Silke, Sarwal, Minnie M, Vitalone, Matthew   +3 more
core   +3 more sources

Prognostic Implications of Sleep Architecture for Patients Admitted to the Intensive Care Unit With Status Epilepticus

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Status epilepticus (SE) is associated with significant mortality. Sleep architecture may reflect normal brain function. Impaired sleep architecture is associated with poorer outcomes in numerous conditions. Here we investigate the association of sleep architecture in continuous EEG (cEEG) with survival in SE.
Ran R. Liu, Marcus C. Ng, Gavin P. Winston, Sabrina Schaly, Garima Shukla, Lysa Boissé Lomax   +5 more
wiley   +1 more source

Clinical and ventilator waveforms of Chinese patients during pressure support ventilation

Scientific Data
In the field of critical care medicine, accurate analysis of physiological waveform data is crucial for clinical decision-making. Although existing public databases provide a wealth of physiological waveform data, publicly available ventilator waveform ...
Xiaozhu Liu, Peng Wang, Chenjia Hao, Ming-Yue Miao, Xu An, Shan-Shan Xu, Yuefu Wang, Hong-Liang Li, Zongmei Tian, Jian-Xin Zhou   +9 more
doaj   +1 more source

Transfusion related acute lung injury presenting with acute dyspnoea: a case report

Journal of Medical Case Reports, 2008
Introduction Transfusion-related acute lung injury is emerging as a common cause of transfusion-related adverse events. However, awareness about this entity in the medical fraternity is low and it, consequently, remains a very under-reported and often an
Haji Altaf, Sharma Shekhar, Vijaykumar DK, Paul Jerry   +3 more
doaj   +1 more source

Time course of lung injury in rat acute pancreatitis [PDF]

, 2018
Objective: Lung injury is asevere complication of acute pancreatitis that increases the mortality rate of the disease. The pathophysiology of acute pancreatitis has been studied in several experimental models, but the kinetics of pulmonary complications ...
Cikirikcioglu, Banu, Frossard, Jean-Louis, Morel, Denis, Pastor, Catherine, Tapponnier, Maxime   +4 more
core  

Coagulation and anticoagulation in idiopathic pulmonary fibrosis [PDF]

, 2015
Idiopathic pulmonary fibrosis (IPF) is an incurable, progressive interstitial lung disease with a prognosis that is worse than that of many cancers. Epidemiological studies have demonstrated a link between IPF and thrombotic vascular events.
Crooks, Michael G., Hart, Simon P.
core   +3 more sources