Results 201 to 210 of about 325,916 (299)

METTL3-m6A methylation inhibits the proliferation and viability of type II alveolar epithelial cells in acute lung injury by enhancing the stability and translation efficiency of Pten mRNA [PDF]

Qiuyun Wang, Jie Shen, Shiyuan Luo, Zhize Yuan, Shiyou Wei, Qiang Li, Qianzi Yang, Yan Luo, Lei Zhuang   +8 more
openalex   +1 more source

Chaperone‐Mediated Autophagic Degradation of USP9X in Macrophages Exacerbates Postmyocardial Infarction Inflammation and Cardiac Dysfunction

Advanced Science, EarlyView.
This study demonstrates that inflammatory stimuli induce the acetylation‐triggered, chaperone‐mediated autophagic degradation of ubiquitin‐specific peptidase 9 X‐linked (USP9X) in macrophages. USP9X acts as a macrophage “inflammation switch” after myocardial infarction (MI). USP9X loss destabilizes tumor necrosis factor receptor‐associated factor (TRAF)
Biqing Wang, Xiangheng Cai, Mengqi Li, Xue Liu, Junhui Xue, Ye Liu, Ding Ai, Xinyang Hu   +7 more
wiley   +1 more source

Fcer1g and St3gal1: Macrophage-associated angiogenesis biomarkers and therapeutic targets in sepsis-induced acute lung injury. [PDF]

PLoS One
Liu L, Luo P, Wang M, Yu S, Xiao J.
europepmc   +1 more source

Recent developments of small molecules with anti-inflammatory activities for the treatment of acute lung injury

, 2020
Tianpeng Chen, Gaoyang Zhu, Xiangwei Meng, Xingxian Zhang   +3 more
openalex   +1 more source

A Dual‐Responsive Versatile Nanohybrid Orchestrating Tumor Elimination and Tumor‐Associated Osteolysis Restoration via Sequential Release

Advanced Science, EarlyView.
The versatile CaO2@CuMOF@HAP nanohybrid demonstrates an outstanding MMP9/pH‐triggered release performance for sequential release of osteogenic growth peptide into deep‐seated tumor‐infiltrated bone destruction areas and dual ions into tumor cells, enabling efficient tumor‐associated osteolysis restoration and tumor elimination for more comprehensive ...
Lan Liu, Han‐Zhe Liu, Zhe‐Nan Liu, Tong Wang, Li‐Li Yu, Qiu‐Jing Li, Zi‐Yi Chen, Guo‐Feng Luo, Zheng‐Jun Shang   +8 more
wiley   +1 more source

Bmi1 deficiency exacerbates hyperoxia-induced acute lung injury in mice. [PDF]

Front Physiol
Hernández-Cuervo H, Soundararajan R, Patil SS, Breitzig MT, Alleyn M, Narala VR, Lockey R, Galam L, Kolliputi N.   +8 more
europepmc   +1 more source

MiR-199a-3p Attenuates Sepsis-Induced Acute Lung Injury by Targeting NLRP1 and Suppressing Caspase-1/GSDMD-Mediated Pyroptosis in a CLP Rat Model [PDF]

Wenhan Xia, Liming Liu, Xingmi Ye, Huiwei He, Cong Wang   +4 more
openalex   +1 more source

Nature‐Inspired Surface Modification Strategy Reverses the Autophagic Flux Impairment of Mitochondrial Transplantation for Attenuating Ischemic Strokes

Advanced Science, EarlyView.
The functionalized starch modifies the mitochondrial surface and encapsulates resveratrol into the cavity of helices, facilitating a novel mitochondrial transplantation platform (MLSR). Upon internalization in recipient cells, MLSR triggers mitophagy and maintains positive autophagic flux through RIP1/RIP3 pathway inhibition.
Nisha Wang, Qiyang Ding, Lei Shi, Ji Xia, Shuyue Zhang, Chenxin Jian, Yixiao Yan, Xiuhua Luo, Jiarui Wang, Ming Cheng, Yiqiong Jia, Hao Tian, Wei Gao   +12 more
wiley   +1 more source

Tristetraprolin protects against ozone-induced acute lung injury and inflammation in mice. [PDF]

J Immunol
Lamichhane R, Choudhary I, Singamsetty D, Patial S, Saini Y.   +4 more
europepmc   +1 more source