Results 51 to 60 of about 3,455,272 (209)
Mechanisms of Lung Injury in a Mouse Model of Bronchopulmonary Dysplasia [PDF]
, 2009 Bronchopulmonary dysplasia (BPD) is a chronic lung disease that affects preterm infants. Increased levels of inflammatory mediators in the amniotic fluid and in the lungs of preterm infants are associated with the development of BPD.
Hogmalm, Anna
core +1 more source
Biomarkers in acute lung injury [PDF]
Translational Research, 2012 Acute respiratory distress syndrome (ARDS) and acute lung injury (ALI) result in high permeability pulmonary edema causing hypoxic respiratory failure with high morbidity and mortality. As the population ages, the incidence of ALI is expected to rise. Over the last decade, several studies have identified biomarkers in plasma and bronchoalveolar lavage ...
Maneesh, Bhargava, Chris H, Wendt
openaire +2 more sources
Beta Agonist Lung Injury TrIal-2 (BALTI-2) trial protocol : a randomised, double-blind, placebo-controlled of intravenous infusion of salbutamol in the acute respiratory distress syndrome [PDF]
, 2011 Background: The Acute Respiratory Distress Syndrome (ARDS) is a common cause of respiratory failure in critically ill patients. Experimental studies suggest that treatment with beta agonists may be helpful in ARDS.
McCabe Chris +21 more
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CXCR2 in Acute Lung Injury [PDF]
Mediators of Inflammation, 2012 In pulmonary inflammation, recruitment of circulating polymorphonuclear leukocytes is essential for host defense and initiates the following specific immune response. One pathological hallmark of acute lung injury and acute respiratory distress syndrome is the uncontrolled transmigration of neutrophils into the lung interstitium and alveolar space ...
Konrad, Franziska Magdalena +1 more
openaire +4 more sources
Nature Communications, 2021 The serine protease TMPRSS2 primes SARS-CoV-2 glycoprotein for cell entry. Here, the authors perform a screen to identify drugs that reduce TMPRSS2 expression and find that halofuginone modulates proteasome-mediated degradation of TMPRSS2 and reduces ...
Yanwen Chen +16 more
doaj +1 more source
BMJ OpenIntroduction The optimal method for conducting spontaneous breathing trials (SBTs) remains a subject of ongoing debate. High-flow oxygen via endotracheal tube (HFOT) has emerged as a novel alternative for SBTs.
Ming-Yue Miao +4 more
doaj +1 more source
Internal Medicine, 2009 The first report of acute respiratory distress syndrome (ARDS) was published in 1967, and even now acute lung injury (ALI) and ARDS are severe forms of diffuse lung disease that impose a substantial health burden all over the world. Recent estimates indicate approximately 190,000 cases per year of ALI in the United States each year, with an associated ...
Tsushima, Kenji +5 more
openaire +3 more sources
, 2020 Introduction: Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are acute onset syndromes affecting the lungs, which develop for several reasons and are characterized by hypoxemia and diffuse lung infiltration.
Serdar Kalemci +14 more
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Platelet-activating factor receptor plays a role in lung injury and death caused by influenza A in mice [PDF]
, 2010 Influenza A virus causes annual epidemics which affect millions of people worldwide. A recent Influenza pandemic brought new awareness over the health impact of the disease.
Sousa, Lirlandia P. +60 more
core +2 more sources
Redox Biology, 2022 It is increasingly recognized that cigarette smoke (CS) exposure increases the incidence and severity of acute respiratory distress syndrome (ARDS) in critical ill humans and animals. However, the mechanism(s) is not well understood.
Alexis White +13 more
doaj +1 more source