Immunotherapy strategies and prospects for acute lung injury: Focus on immune cells and cytokines
Frontiers in Pharmacology, 2022 Acute lung injury/acute respiratory distress syndrome (ALI/ARDS) is a disastrous condition, which can be caused by a wide range of diseases, such as pneumonia, sepsis, traumas, and the most recent, COVID-19.
Wenfang Zhu, Yiwen Zhang, Yinghong Wang
doaj +1 more source
The role of ubiquitination and deubiquitination in the regulation of cell junctions
Protein & Cell, 2017 Maintenance of cell junctions plays a crucial role in the regulation of cellular functions including cell proliferation, permeability, and cell death.
Junting Cai +3 more
doaj +1 more source
Динаміка показників легеневого ушкодження за умови експериментального HCl-індукованого гострого ураження легень = Dynamics of pulmonary damage parameters in experimental HCl-induced acute lung injury [PDF]
, 2014 Hryshchuk L. A., Besky V. O., Marushchak M. I. Динаміка показників легеневого ушкодження за умови експериментального HCl-індукованого гострого ураження легень = Dynamics of pulmonary damage parameters in experimental HCl-induced acute lung injury ...
Besky, V. O. +2 more
core +1 more source
Leukocyte sequestration in pulmonary microvessels and lung injury following systemic complement activation in rabbits [PDF]
, 1999 Inflammatory reactions are associated with sequestration of leukocytes in the lung. Complement activation leads to accumulation of leukocytes in alveolar septa and alveoli, to lung edema and hemorrhage.
Kuhnle, Gerhard E. H. +5 more
core +1 more source
, 2018 A wide variety of insults can produce acute lung damage, inclusive of those that injure the lungs directly. The clinical syndrome of acute onset respiratory distress, dyspnea, and bilateral infiltrates is referred to as acute respiratory distress syndrome.
Cheung O. -Y., Graziano P., Smith M. L.
openaire +2 more sources
CpG oligonucleotide activates Toll-like receptor 9 and causes lung inflammation in vivo [PDF]
, 2007 Background Bacterial DNA containing motifs of unmethylated CpG dinucleotides (CpG-ODN) initiate an innate immune response mediated by the pattern recognition receptor Toll-like receptor 9 (TLR9).
Schwederski Markus +21 more
core +1 more source
Lung volume recruitment maneuvers and respiratory system mechanics in mechanically ventilated mice [PDF]
, 2009 The study aim was to establish how recruitment maneuvers (RMs) influence lung mechanics and to determine whether RMs produce lung injury. Healthy BALB/c mice were allocated to receive positive end-expiratory pressure (PEEP) at 2 or 6 cmH2O and volume ...
Sly, P.D. +20 more
core +1 more source
Hyperoxia and acute lung injury
American Journal of Physiology-Lung Cellular and Molecular Physiology, 2008 to the editor: The review by Matute-Bello et al. ([15][1]) has misleading and potentially dangerous statements concerning the role of hyperoxia in human acute lung injury (ALI). Table 4 states “in normal human lungs, 100% oxygen has not induced lung injury … ” The text states that ...
Aron B, Fisher, Michael F, Beers
openaire +3 more sources
Mediators of Inflammation, 2017 Maintenance of pulmonary endothelial barrier integrity is important for reducing severity of lung injury. Lysophosphatidic acid (LPA) regulates cell motility, cytoskeletal rearrangement, and cell growth.
Junting Cai +4 more
doaj +1 more source
Macrolides for Acute Lung Injury [PDF]
Chest, 2012 In this issue of CHEST (see page 1153), Walkey and Wiener1 examine the association between receipt of a macrolide antibiotic and mortality in patients with acute lung injury (ALI). The authors used existing, publicly available data from the Acute Respiratory Distress Network (ARDSNet) Lisofylline and Respiratory Management of Acute Lung Injury (LARMA ...
Michael J, Noto, Arthur P, Wheeler
openaire +2 more sources