Results 161 to 170 of about 223,598 (343)

An Integrated Method to Evaluate the Treatment Efficacy and Immunogenicity of B‐Cell Acute Lymphoblastic Leukemia Therapeutic Enzyme Formulations

open access: yesSmall Methods, EarlyView.
This work presents an integrated set of methods to evaluate the efficacy of asparaginase formulations against B‐cell Acute Lymphoblastic Leukemia (ALL) in mice, including the establishment of an ALL murine model, an amino acid depletion study using high‐performance liquid chromatography (HPLC), and comprehensive assessment of antibody production ...
Julien Santelli   +6 more
wiley   +1 more source

Altered expression of DNMT3A gene in B-cell acute lymphoblastic leukemia by mercaptopurine

open access: diamond, 2021
Seyedhossein Hekmatimoghaddam   +4 more
openalex   +1 more source

Imaging of Abdominal Complications in Children With Acute Lymphoblastic Leukaemia

open access: yesJournal of Medical Imaging and Radiation Oncology, EarlyView.
ABSTRACT Acute lymphoblastic leukaemia (ALL) is the most common paediatric malignancy and remains one of the most common causes of cancer‐related death in children and adolescents. Five‐year overall survival rates now exceed 90% with current multidrug chemotherapeutic regimens. This improvement, coupled with the toxicity of chemotherapy, has led to the
Luke R. Holmes   +2 more
wiley   +1 more source

Clinical validation of the nursing diagnosis of inadequate nutritional intake in children with cancer

open access: yesInternational Journal of Nursing Knowledge, EarlyView.
Abstract Purpose To clinically validate the nursing diagnosis “Inadequate Nutritional Intake” based on elements identified within a specific situation theory framework in the context of children with cancer. Methods This is a diagnostic accuracy study following the Standards for Reporting Diagnostic Accuracy Studies (STARD) protocol.
Iane Ximenes Teixeira   +7 more
wiley   +1 more source

Age‐ and Sex‐Adjusted Body Mass Index Increases in Childhood Acute Lymphoblastic Leukaemia Patients From Diagnosis to Five‐Year Follow‐Up

open access: yesActa Paediatrica, EarlyView.
ABSTRACT Aim Children with acute lymphoblastic leukaemia (ALL) are at risk of metabolic and cardiovascular complications. We evaluated the development of overweight and obesity for 5 years after diagnosis in children and adolescents treated for ALL. Methods The medical records of children diagnosed with ALL at one centre during 2000–2018 were assessed.
Aino Kytömäki   +4 more
wiley   +1 more source

Burden of haematological malignancies among children, adolescents and young adults: Global and high‐income region insights from the GBD 2021 study

open access: yesBritish Journal of Haematology, EarlyView.
Summary This study provides a comprehensive assessment of haematological malignancies among children, adolescents and young adults aged 0–24 years, using data from the Global Burden of Disease 2021 across 204 countries from 1990 to 2021. We found that global incidence and prevalence remained relatively stable, with approximately 150 000 new cases and ...
Shujuan Xu   +4 more
wiley   +1 more source

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