Results 151 to 160 of about 1,599,857 (245)

DHX15 affects AML1-ETO9a splicing together with HNRNPL, RBM33 in AML1-ETO-positive acute myeloid leukaemia. [PDF]

Br J Haematol
Liu Q, Wang X, Fan J, Zheng Y, Ye L, Chang W, Chen X, Cai Y, Lai X, Li Y, Pan L, Li X, Lin R, Wang S.   +13 more
europepmc   +1 more source

A practical difference from the normal approach to evaluate natural killer (NK) cells and NK cell neoplasms by flow cytometry

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Natural killer (NK) cell neoplasms span indolent to highly aggressive entities, and flow cytometric immunophenotyping is central to their detection and classification. However, distinguishing reactive from neoplastic NK cell expansions can be challenging because NK cells lack somatically recombined antigen receptors, and reactive states may ...
Aaron J. Wilk, Afshin Shameli, Erik Ames, Jonathan R. Fromm, Bartosz Grzywacz, Min Shi, Sindhu Cherian, Jean Oak   +7 more
wiley   +1 more source

Appearances can be deceptive: acute myeloid leukaemia simulating chronic lymphocytic leukaemia. [PDF]

Adv Lab Med
Horsefield BG, García DC, Garzó Moreno A, Tuset Andujar E, Sierra LS, Querol MS.   +5 more
europepmc   +1 more source

Old data, new tricks: Comprehensive computational analysis of 10 years of multi‐center EuroFlow acute myeloid leukemia diagnostic immunophenotypic data

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Acute myeloid leukemia (AML) is characterized by high genotypic and immunophenotypic heterogeneity. We collected an extensive dataset containing 5366 flow cytometry files from 885 AML patients, stained with the EuroFlow acute leukemia orientation tube (ALOT) and AML/MDS panel, acquired in a standardized way at eight centers over a period of 10 
Sarah Bonte, Rosan Olsman, Sofie Van Gassen, Sergio Matarraz, Neus Villamor, Stefan Nierkens, Paula Fernandez, Elaine Sobral da Costa, Carmen‐Mariana Aanei, Alberto Orfao, Jacques J. M. van Dongen, Yvan Saeys, Mattias Hofmans, Vincent H. J. van der Velden   +13 more
wiley   +1 more source

Targeting oncogenic FLT3 uncovers a ferroptosis vulnerability through selenocysteine recoding in acute myeloid leukaemia. [PDF]

Nat Cell Biol
Li M, Zhu Y, Kageyama Y, Furudate K, Kitano A, Tan T, Feng M, Zhou J, Wang T, Taylor RJ, Stevens AM, Samee MAH, Magee JA, Takahashi K, Nakada D.   +14 more
europepmc   +1 more source

Subset‐specific and tissue‐specific expression of NK‐cell markers and killer immunoglobulin‐like receptors: Implications for NK‐cell clonality assessment

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Accurate immunophenotypic evaluation of natural killer (NK)‐cell neoplasms is challenging because NK‐cells lack somatically rearranged antigen receptors, are comprised of phenotypically distinct subsets, and exhibit tissue‐specific subset distribution. We developed a flow cytometry (FC) panel for NK‐cell immunophenotypic analysis and clonality
Valerie Woodings, Orrin Koepke, Jason E. Love, Alireza Torabi, Lianqun Qiu, Jonathan R. Fromm, Sindhu Cherian, Afshin Shameli   +7 more
wiley   +1 more source

<i>Additional sex combs-like 1</i> variants in an acute myeloid leukaemia and a general elderly cohort in central South Africa. [PDF]

Afr J Lab Med
Bergman MV, Kloppers JF, Bester PA, van Marle AC.   +3 more
europepmc   +1 more source

Challenges and Pitfalls to Diagnosing NUTM1‐Rearranged Neoplasia of the Pancreas by Cytology and Ancillary Studies

Diagnostic Cytopathology, EarlyView.
ABSTRACT Fine‐needle aspiration cytology specimens are frequently utilized for ancillary studies to identify diagnostic and prognostic information. This case highlights diagnostic pitfalls and challenges in diagnosing NUTM1‐rearranged neoplasia on pancreatic cytology.
Terrance J. Lynn
wiley   +1 more source

The myeloid cell leukaemia-1 inhibitor MIK665 is a potent therapy in preclinical models of paediatric acute myeloid leukaemia. [PDF]

Br J Haematol
Connerty P, Colgan JN, El-Najjar F, Henry E, Xie J, Idais D, Gentile C, Mao J, Dolman MEM, Marshall GM, Lock RB.   +10 more
europepmc   +1 more source

Differentiation therapy in acute myeloid leukaemia: molecular basis, clinical progress, and future perspectives. [PDF]

Front Med (Lausanne)
Asiri A.
europepmc   +1 more source