Results 1 to 10 of about 90,559 (117)

Immunophenotypic patterns in paediatric acute leukaemia: A flowcytometry-based prospective observational study in tribal dominant state, Jharkhand [PDF]

open access: yesJournal of Family Medicine and Primary Care
Introduction: Acute leukaemia is a rapidly progressive haematopoietic disorder affecting bone marrow, leading to excessive production of immature blast cells. Acute myeloid leukaemia (AML) in adults accounts for 80–90% of cases of acute leukaemia.
Rashmi Rati   +5 more
doaj   +2 more sources

Flow cytometric characterisation of acute leukaemia in adolescent and adult Ethiopians [PDF]

open access: yesAfrican Journal of Laboratory Medicine
Background: Flow cytometric characterisation of acute leukaemia is a key diagnostic approach for clinical management of patients, but is minimally practised in resource-constrained settings like Ethiopia.
Jemal Alemu   +6 more
doaj   +2 more sources

Classification of Acute Leukaemia based on Blast Morphology, Cytochemistry and Flow Cytometry [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2023
Introduction: Acute leukaemias are a heterogeneous group of malignancies due to the abnormal proliferation of immature cells. The classification of acute leukaemia has been transformed over a period.
P Jubit Paulose, J Latha Fathima
doaj   +1 more source

Unusual Presentation of Acute Leukaemia: A Tripod of Cases [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2016
Acute Leukaemia is one of the common haematological malignancies encountered with varied clinical and haematological presentation. In acute leukaemia, complications like bleeding and infection cause significant morbidity and mortality, thus ...
Manjari Kishore   +3 more
doaj   +1 more source

OSR1 suppresses acute myeloid leukaemia cell proliferation by inhibiting LGR5-mediated JNK signalling

open access: yesAutoimmunity, 2021
Odd-skipped related transcription factor 1 (OSR1) is implicated in various pathophysiologic processes, such as embryonic heart and urogenital formation, and functions as a tumour suppressor in diverse tumours.
Lingyan Zong, Yingxin Sun
doaj   +1 more source

Correlation of Bone Marrow Morphology and Immunophenotyping in Acute Leukaemia Patients

open access: yesHaematology Journal of Bangladesh, 2020
Background: Acute leukaemia (AL) is a malignant disorder of the blood that is characterized by blocked or impaired differentiation of haemopoietic stem cells, resulting in abnormal accumulation of immature precursors and suppression of growth and ...
Muhammad Nurul Farhad   +3 more
doaj   +1 more source

Leukaemia Cutis: Clinical Features and Outcomes of 56 Patients

open access: yesActa Dermato-Venereologica, 2022
Leukaemia is a malignant neoplasm of the haematopoietic system. Cutaneous manifestations of leukaemia are called leukaemia cutis, and are regarded as a sign of poorer prognosis and shorter survival time.
Hwa Jung Yook   +8 more
doaj   +1 more source

Immunotherapy in leukaemia

open access: yesActa Biochimica et Biophysica Sinica, 2023
Leukaemia is the common name for a group of malignant diseases of the haematopoietic system with complex classifications and characteristics. Remarkable progress has been made in basic research and preclinical studies for acute leukaemia compared to that
Mu Xingmei   +7 more
doaj   +1 more source

Acute leukemia in pregnancy: a single institutional experience with 21 cases at 10 years and a review of the literature

open access: yesAnnals of Medicine, 2021
Introduction Acute leukemia (AL) occurring in pregnancy is extremely rare, and its treatment is a clinical dilemma.Methods We retrospectively reviewed the medical records of our hospital from 2010 to 2019.Results Twenty-one patients were diagnosed with ...
Dengqin Zhu   +4 more
doaj   +1 more source

T-cell acute lymphoblastic leukaemia, mild leucocytosis causes severe tumour lysis syndrome

open access: yesAdvances in Human Biology, 2019
Tumour lysis syndrome (TLS) is a potentially life-threatening complication of the tumour. This syndrome consists of laboratory parameters such as hyperuricaemia, hyperkalaemia, hyperphosphataemia and hypocalcaemia and clinical complications such as ...
Dilshad Jahan, Mainul Haque
doaj   +1 more source

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