Results 21 to 30 of about 1,570,861 (237)

Rare additional chromosomal abnormalities in acute promyelocytic leukaemia resulting in rapidly fatal disease: report of a case

eJHaem, 2022
Background Acute promyelocytic leukaemia results from reciprocal translocation between the long arms of chromosomes 15 and 17. This translocation leads to the formation of chimeric gene, which is both the diagnostic marker as well as the therapeutic ...
Ahmed Maseh Haidary, Sarah Noor, Sahar Noor, Maryam Ahmad, Ahmad Walid Yousufzai, Ramin Saadaat, Zeeshan Ansar Ahmed, Abdul Jamil Rasooli, Ahmad Shekib Zahier, Haider Ali Malakzai, Abdul Sami Ibrahimkhil, Samuel Sharif, Mohammad Sarwar Anwari, Abdul Hadi Saqib, Tawab Baryali, Najla Nasir   +15 more
doaj   +1 more source

Erythrocytic Pyruvate Kinase and Malondialdehyde Levels in Acute Leukaemia Patients [PDF]

Journal of Clinical and Diagnostic Research, 2012
Introduction: Many acquired enzymopathies have been reported in patients with acute leukaemia. Oxidative stress is also found to be increased in acute leukaemia, which can be indicated by the increased malondialdehyde (MDA) levels.
Veena Singh, Munish Kaushik, Kiran Dahiya, P.S. Ghalaut, Rakesh Dhankhar, Ragini Singh   +5 more
doaj  

Acute disseminated encephalomyelitis mimicking late CNS relapse of acute lymphoblastic leukaemia: case report

Journal of Medical Case Reports, 2007
Background Acute encephalomyelopathy occurring after an allogeneic bone marrow transplant for leukaemia is a diagnostic emergency. The diagnosis can be challenging since there is a wide set of alternative diagnoses, including opportunistic infections and
Kumar Ram, Nijalingappa Shobha, Grainger John, Ismayl Omar   +3 more
doaj   +1 more source

Acute Leukaemia [PDF]

, 2020
Acute lymphoblastic leukaemia occurs with a frequency of 3.3 per 100,000 children and acute myeloid leukaemia with a frequency of 0.7 per 100,000 children aged
Andrea Jarisch, Gökbuget, Nicola, von Wolff, Michael, Michael von Wolff, Jarisch, Andrea, Nicola Gökbuget   +5 more
core   +1 more source

Enhancer RNAs contribute to genome reprogramming driven by a GATA3 noncoding variant in leukaemia

Scientific Reports
The GATA3 noncoding variant rs3824662 has been implicated in the pathogenesis of Ph-like B-ALL, where it is associated with extensive chromatin reorganisation, resulting in the dysregulation of multiple genes, including CRLF2 overexpression.
Thayana da Conceição Barbosa, Caroline Pires Poubel, Ana Luiza Tardem Maciel, Caroline Barbieri Blunck, Rafael Lima dos Santos, Mariana Boroni, Marcela Braga Mansur, Mariana Emerenciano   +7 more
doaj   +1 more source

Myeloid Sarcoma Presenting as Nasal and Orbital Mass: An Initial Manifestation of an Acute Myeloid Leukaemia [PDF]

Journal of Clinical and Diagnostic Research, 2017
Myeloid sarcoma is an extramedullary manifestation of Acute Myeloid Leukaemia and sometimes is the only indicator of the disease. The incidence varies between 3-9.1% of acute leukaemia cases.
Amita Jain Gupta, Shramana Mandal, Richa Gupta, Nita Khurana, Achal Gulati   +4 more
doaj   +1 more source

The Impact of the COVID‐19 Pandemic on Childhood Cancer Survival: A Population‐Based Assessment of Survival Patterns Between 2015 and 2023 in Germany

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Numerous international studies have reported declines in new cancer diagnoses, delayed diagnoses and disruptions in cancer treatment following the implementation of COVID‐19 pandemic public health measures, raising concerns that these effects may ultimately contribute to increased cancer mortality.
Friederike Erdmann, Maike Wellbrock, Javier Louro, Arndt Borkhardt, Martin Schrappe, Claudia Trübenbach, Desiree Grabow, Cécile M. Ronckers, Joachim Schüz   +8 more
wiley   +1 more source

Referral Patterns and Diagnostic Timeliness in Pediatric Cancer: A Hospital‐Based Study in Indonesia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Timely diagnosis and treatment are critical for improving survival among children with cancer. In low‐ and middle‐income countries (LMICs), delays are common and may be influenced by fragmented referral pathways and diagnostic limitations.
Nur Melani Sari, Regina Hadi Putri, Fatimah Assyifa, Judith Spijkerman, Gertjan Johannes Kaspers, Susi Susanah   +5 more
wiley   +1 more source

The detection and classification of blast cell in Leukaemia Acute Promyelocytic Leukaemia (AML M3) blood using simulated annealing and neural networks [PDF]

, 2011
This paper was delivered at AIME 2011: 13th Conference on Artifical Intelligence in Medicine.This paper presents a method for the detection and classification of blast cells in M3 with others sub-types using simulated annealing and neural networks.
Ismail, W, Swift, S, Hassan, R, Payne, A
core   +6 more sources

Severe Wernicke encephalopathy and acute pancreatitis due to all-trans-retinoic acid and arsenic trioxide during treatment of acute promyelocytic leukaemia: a case report

Journal of International Medical Research, 2020
A 55-year-old woman developed acute promyelocytic leukaemia during treatment with all-trans-retinoic acid and arsenic trioxide. Initially, she presented with symptoms of epigastric pain, vomiting, and nausea, and she developed acute pancreatitis. She was
Yan Jiang, Linhua Ji
doaj   +1 more source