Results 201 to 210 of about 185,904 (310)

Clinical validation of a real‐time machine learning‐based system for the detection of acute myeloid leukemia by flow cytometry

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Machine‐learning (ML) models in flow cytometry have the potential to reduce error rates, increase reproducibility, and boost the efficiency of clinical labs. While numerous ML models for flow cytometry data have been proposed, few studies have described the clinical deployment of such models.
Lauren M. Zuromski, Jacob Durtschi, Aimal Aziz, Jeffrey Chumley, Mark Dewey, Paul English, Muir Morrison, Keith Simmon, Blaine Whipple, Brendan O'Fallon, David P. Ng   +10 more
wiley   +1 more source

BCR::ABL1-Positive Acute Myeloid Leukemia. [PDF]

Am J Hematol
Canali A, Rieu JB, Lapierre L, Bain BJ.
europepmc   +1 more source

Unraveling genotype–phenotype associations and predictive modeling of outcome in acute myeloid leukemia

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Acute myeloid leukemia (AML) comprises 32% of adult leukemia cases, with a 5‐year survival rate of only 20–30%. Here, the immunophenotypic landscape of this heterogeneous malignancy is explored in a single‐center cohort using a novel quantitative computational pipeline.
Artuur Couckuyt, Sofie Van Gassen, Annelies Emmaneel, Vince Janda, Malicorne Buysse, Ine Moors, Jan Philippé, Mattias Hofmans, Tessa Kerre, Yvan Saeys, Sarah Bonte   +10 more
wiley   +1 more source

CD36 as a marker of acute myeloid leukemia prognosis: A systematic review. [PDF]

Hematol Transfus Cell Ther
Amantéa MC, da Silva RP, Soares LR, Pereira JLM, de Souza APD.   +4 more
europepmc   +1 more source

Genetic profile of ASXL1 gene in risk assessment in acute myeloid leukemia. [PDF]

BMC Genom Data
Bamusa SA, Qureshi W, Gohar A, Irfan M, Khan IA, Shakeel M.   +5 more
europepmc   +1 more source

RORγt‐APCs: The New Masters of Oral Tolerance

Barrier Immunity, EarlyView.
ABSTRACT Oral tolerance is defined by the hypo‐responsiveness of our body to fed antigens, and its failure can lead to immune‐mediated diseases, such as allergy, chronic inflammation and autoimmune diseases. Decades of research have demonstrated that antigen‐presenting cells (APCs) promote oral tolerance by inducing regulatory T cells (Tregs) and/or ...
Thierry Gauthier, WanJun Chen
wiley   +1 more source

Acute dyspnoea in cancer patients: Prevalence of acute heart failure, resource use and diagnostic accuracy of natriuretic peptides

European Journal of Heart Failure, EarlyView.
Cancer patients presenting to the emergency department ED with dyspnoea. Among 2153 patients presenting to the ED with dyspnea, 473 (22.0%) had an active or past cancer. Acute heart failure (AHF) was the most common final diagnosis in both groups. Pneumonia and cancer‐related dyspnoea were more common in cancer patients.
Paolo Bima, Desirée Wussler, Pedro Lopez‐Ayala, Maria Belkin, Albina Nowak, Xueting Lin, Ivo Strebel, Fabiana Sgueglia, Eleni Michou, Androniki Papachristou, Laureve Chollet, Codruta Popescu, Nikola Kozhuharov, Samyut Shrestha, Gabriela Kuster, Katharina Rentsch, Arnold Von Eckardstein, Mascha Binder, Felix Mahfoud, Tobias Breidthardt, Christian Mueller   +20 more
wiley   +1 more source

Correction: Venetoclax efficacy on acute myeloid leukemia is enhanced by the combination with butyrate. [PDF]

Sci Rep
Kawakatsu R, Tadagaki K, Yamasaki K, Yoshida T.   +3 more
europepmc   +1 more source

Prognostic significance of somatic mutations in myeloid cells of men with chronic heart failure – interaction between loss of Y chromosome and clonal haematopoiesis

European Journal of Heart Failure, EarlyView.
Abstract Aims Age‐associated clonal haematopoiesis of indeterminate potential (CHIP) has been linked to increased incidence and worse prognosis of chronic heart failure (CHF). CHIP arises from somatic mutations in haematopoietic stem and progenitor cells. Mosaic loss of Y chromosome (LOY), the most common somatic mutation in male blood cells, increases
Sebastian Cremer, Moritz von Scheidt, Klara Kirschbaum, Lukas Tombor, Silvia Mas‐Peiro, Wesley Abplanalp, Tina Rasper, Akshay Ware, Andrin Schuff, Alexander Berkowitsch, Johannes Krefting, David Leistner, Heribert Schunkert, Thimoteus Speer, Stefanie Dimmeler, Andreas Michael Zeiher   +15 more
wiley   +1 more source

Gallbladder Myeloid Sarcoma Associated With NPM1 Mutated Acute Myeloid Leukemia. [PDF]

EJHaem
Grimaldi F, Rascato MG, Mainenti PP, Giordano M, Mascolo M, Pane F.   +5 more
europepmc   +1 more source