Results 221 to 230 of about 311,440 (293)

A new recurrent inversion, inv(7)(p15q34), leads to transcriptional activation of HOXA10 and HOXA11 in a subset of T-cell acute lymphoblastic leukemias [PDF]

, 2005
Benoit, Yves, BILLIET, J, BOOGAERTS, M, Cauwelier, Barbara, COOLS, J, DASTUGUE, N, De Moerloose, Barbara, De Paepe, Anne, GRAUX, C, HAGEMEIJER, A, HUGUET, F, MARYNEN, P, Poppe, Bruce, ROBERT, A, SELLESLAG, D, Speleman, Franki, UYTTEBROECK, A, Van Roy, Nadine, VANDENBERGHE, P, Vandesompele, Jo, Verhasselt, Bruno   +20 more
core  

Differentiation Syndrome and Sweet Syndrome‐Like Overlap Following Venetoclax–Azacytidine and G‐CSF Therapy

JEADV Clinical Practice, EarlyView.
ABSTRACT Differentiation syndrome (DS) and Sweet syndrome (SS) are inflammatory complications mediated by cytokine dysregulation, classically associated with therapies that promote myeloid differentiation or cytokine release. While DS has been primarily linked to all‐trans retinoic acid (ATRA) and IDH inhibitors, recent evidence suggests that ...
Katerina Grafanaki, Maria Gerbesi, Zoe Apalla, Dimitrios Tsokanas, Efstathia Pasmatzi, Alexandros Spyridonidis, Maria Liga   +6 more
wiley   +1 more source

m6A Modification of ATOX1 Inhibits Acute Myeloid Leukemia Progression by Promoting Cuproptosis. [PDF]

Cancer Res Commun
Peng J, Fu X, Li S, Hu C, Zhao X, Peng J.   +5 more
europepmc   +1 more source

Fat Mass and Obesity‐Associated Protein Contributes to Tumorigenesis and Drug Resistance of Diffuse Large B‐Cell Lymphoma by Suppressing N6‐Methyladenosine Methylation of Myc

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Ibrutinib resistance remains a major obstacle in the treatment of diffuse large B‐cell lymphoma (DLBCL). Fat mass and obesity‐associated protein (FTO) has been implicated in drug resistance through its regulation of N6‐methyladenosine (m6A) modifications; however, whether FTO mediates ibrutinib resistance in DLBCL remains unclear.
Ting‐Ting Lu, Jin‐Hao Chen, Yan‐Fang Wang, Xiao Wu, Hui‐Yun Ni, Qiu‐Rong Zhang   +5 more
wiley   +1 more source

Inside the Battle Against Acute Myeloid Leukemia: Biology, Breakthroughs, and Hope. [PDF]

Cells
Bao J, Freund O, Sund L, Du W.
europepmc   +1 more source

Oncogenic KRAS Rewires Stress Granule Dynamics: Mechanisms and Therapeutic Opportunities

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Stress granules (SGs) are dynamic, membrane‐less structures that form in response to various cellular stresses, including metabolic, oxidative, and therapeutic challenges. They function as adaptive hubs and reorganize protein synthesis and signaling networks to help cells survive under stress. In cancer, these condensates are often hijacked to
Msimisi Ndzinisa, Birhanetensay Masresha Altaye, Yuh‐Pyng Sher   +2 more
wiley   +1 more source

CCAAT-enhancer binding protein delta functions as a tumor suppressor gene in acute myeloid leukemia. [PDF]

Neoplasia
Prajapati SC, Meydan C, Neelamraju Y, Wang Z, Atwood G, Paudel BB, Fan H, Dunham N, Dillon R, Gandara JA, Lee T, Sheridan C, Wang S, Zumbo P, Becker MW, Bullinger L, Carroll MP, D'Andrea RJ, Levine RL, Mason CE, Melnick AM, Zang C, Bekiranov S, Garrett-Bakelman FE.   +23 more
europepmc   +1 more source

ZFP36L1 Enhances Microglial Ferroptosis in Ischemic Stroke by Reducing FTO‐Mediated N6‐Methyladenosine Demethylation of ACSL1 mRNA

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Microglia play an important role in ischemic stroke (IS). However, the molecular regulatory mechanisms underlying microglial ferroptosis in IS remain incompletely understood. In this study, blood samples were collected from 20 IS patients and 15 healthy volunteers.
Ai‐Xia Song, Han‐Xu Jin, Yuan‐Xin Sun, Wen‐Hui Kou, Xiao‐Ning Niu, Huan‐Huan Wang, Ting‐Ting Zhong, Ping Gu   +7 more
wiley   +1 more source

Investigation of the expression and potential mechanistic role of BYSL in acute myeloid leukemia. [PDF]

Clin Exp Med
Gao J, Wang F, Chen Y, Wu P, Jia Y, Song X.   +5 more
europepmc   +1 more source

Menin Inhibition in Acute Myeloid Leukemia: Pathobiology, Progress and Promise. [PDF]

Biomedicines
Joshi U, Shallis RM.
europepmc   +1 more source