Results 231 to 240 of about 1,921,670 (307)

Does disease ontogeny matter more than JAK2 mutation status in acute myeloid leukemia? [PDF]

Cancer
Babu NS, Sangeetha KSS.
europepmc   +1 more source

Regulating Lipid Metabolism in Cancer: The Therapeutic Potential of Traditional Chinese Medicine

Phytotherapy Research, EarlyView.
By regulating the reprogramming of lipid metabolism in tumor cells, TCM provides a novel strategy for antitumor therapy with reduced toxicity and enhanced efficacy. ABSTRACT Lipid metabolic reprogramming is a key feature of tumor cells to adapt to the microenvironment and plays an important role in tumor growth, invasion, and metastasis.
Yufeng Gao, Huiming Huang, Xuejiao Wei, Xiaoxue Wang, Wanying Xie, Xinyu Qiu, Fei Wang, Zhuguo Wang, Ruoxin Zhang, Yilin Cai, Changhai Qu, Zhongdong Hu   +11 more
wiley   +1 more source

Targeting the CD47–SIRPα phagocytic checkpoint in cancer: Biology, translational opportunities, and next‐generation therapeutic strategies

Smart Molecules, EarlyView.
The CD47–SIRPα axis has emerged as a critical innate immune checkpoint that suppresses macrophage‐mediated phagocytosis through a canonical “don't eat me” signal and enables tumor immune evasion. We comprehensively summarize the structural and biological features of CD47 and the molecular mechanisms underlying CD47‐mediated regulation of phagocytosis ...
Ruimei Zhou, Lingjie Jing, Jianping Zhang, Cheng Guo, Quanjun Yang   +4 more
wiley   +1 more source

Prognostic impact of CD123 overexpression on the outcome of pediatric acute myeloid leukemia. [PDF]

Front Oncol
Mohammed M, Sidhom I, El-Sharkawy N, Hammad M, Salama M, Soliman S, Yassin D, Salem S, Hamdy N, Elnashar A, Abouelnaga S, Ahmed S, Elhemaly A, Elhaddad A.   +13 more
europepmc   +1 more source

Nutrimental Determinants of Chronological Aging and Competitiveness in the snf1Δ Warburg Model

Yeast, EarlyView.
Deletion of SNF1 in Saccharomyces cerevisiae alters chronological aging in a nutrient‐dependent manner, shortening lifespan under low‐nutrient conditions and extending it under high‐glucose and high‐amino‐acid conditions. Under nutrient‐rich conditions, the snf1∆ strain also showed an approximately 2‐log increase in competitiveness relative to the wild
Abigail Correa‐Olivares, Amanda de la Caridad Lahera Champagne, Alma Delia Bertadillo‐Jilote, Karla I. Lira‐de Leon, David G. Garcia‐Gutierrez, Gerardo M. Nava, Vanessa Sanchez‐Quezada, Luis Alberto Madrigal‐Perez   +7 more
wiley   +1 more source

Interventional oncology in children: Where are we now?

Journal of Medical Imaging and Radiation Oncology, EarlyView.
Abstract Paediatric Interventional Oncology (IO) lags behind adult IO due to a scarcity of specific outcome data. The suboptimal way to evolve this field is relying heavily on adult experiences. The distinct tumour types prevalent in children, such as extracranial germ cell tumours, sarcomas, and neuroblastoma, differ strongly from those found in ...
Premal Amrishkumar Patel, Fernando Gómez Muñoz   +1 more
wiley   +1 more source

Prime salvage treatment for pediatric acute myeloid leukemia. [PDF]

Haematologica
Kaspers GJL.
europepmc   +1 more source

Clinical validation of the nursing diagnosis of inadequate nutritional intake in children with cancer

International Journal of Nursing Knowledge, EarlyView.
Abstract Purpose To clinically validate the nursing diagnosis “Inadequate Nutritional Intake” based on elements identified within a specific situation theory framework in the context of children with cancer. Methods This is a diagnostic accuracy study following the Standards for Reporting Diagnostic Accuracy Studies (STARD) protocol.
Iane Ximenes Teixeira, Natália Cabrera Matos, Marcos Venícios de Oliveira Lopes, Viviane Martins da Silva, Amanda Laryssa Gomes do Nascimento, Yanka Alcântara Cavalcante, Ana Beatriz Oliveira Marques dos Santos, Daniele Paula Alves Mouta   +7 more
wiley   +1 more source

Divergent Clonal Trajectories of FLT3-ITD in Acute Myeloid Leukemia and Their Clinical and Transcriptomic Associations. [PDF]

Hematol Oncol
Tsai XC, Chang YS, Tien FM, Lo MY, Kuo YY, Tseng MH, Peng YL, Yao CY, Yao SC, Lin CC, Ko BS, Yao M, Tien HF, Hou HA, Chou WC.   +14 more
europepmc   +1 more source