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Multimodal analgesia may include pharmacological components such as regional anesthesia, opioid and nonopioid systemic analgesics, nonsteroidal anti-inflammatories, and a variety of adjuvant agents. Multimodal analgesia has been reported for a variety of
Roberta De Jong, Alexander J. Shysh
doaj +1 more source
Background Ketamine infusions have been used for decades to treat acute pain, but a recent surge in usage has made the infusions a mainstay of treatment in emergency departments, in the perioperative period in individuals with refractory pain, and in ...
E. Schwenk+9 more
semanticscholar +1 more source
Multilocular pain syndromes with advanced chronification lead to a significant reduction in the quality of life of patients. The administration of cannabis is currently being discussed in the context of therapy-resistant pain and increasing opiate abuse.
Tobias Romeyke, Rudolf Westfal
doaj +1 more source
A 61-year-old retired farmer started experiencing severe pain in his abdomen for the last 2 weeks along with abdominal distension, vomiting and inability to pass flatus or faeces. He was investigated on admission to our casualty and an abdominal x ray revealed classical features of intestinal obstruction (fig 1).
Suraj Jain+6 more
openaire +4 more sources
The clinical utility of conventional IV opioids is limited by the occurrence of opioid‐related adverse events. Oliceridine is a novel G protein–biased μ‐opioid receptor agonist designed to provide analgesia with an improved safety and tolerability ...
N. Singla+6 more
semanticscholar +1 more source
Epidural Catheter Migration in a Patient with Severe Spinal Stenosis
Establishment of appropriate neuraxial catheter positioning is typically a straightforward procedural undertaking. It can, however, lead to deception of even the most experienced clinician and occur despite the most meticulous attention to detail ...
Daryl I. Smith, Ryan Anderson
doaj +1 more source
Multicentre randomised controlled trial of nasal diamorphine for analgesia in children and teenagers with clinical fractures. [PDF]
OBJECTIVE: To compare the effectiveness of nasal diamorphine spray with intramuscular morphine for analgesia in children and teenagers with acute pain due to a clinical fracture, and to describe the safety profile of the spray.
Kendall, JM+3 more
core +1 more source
Key Points Question Which prospectively assessed descriptor of the acute pain trajectory in the first 10 days after surgery best estimates the likelihood of remote pain resolution, opioid cessation, and patient-reported complete recovery after surgery ...
Jennifer M. Hah+17 more
semanticscholar +1 more source
Parents' beliefs and knowledge about the management of acute otitis media: A qualitative study [PDF]
BACKGROUND: Acute otitis media is a common reason for antibiotic prescribing, despite strong evidence that antibiotics provide minimal benefit. Studies have demonstrated that patients’ (or parents’) expectations of antibiotics often influence general ...
Del Mar, Chris+3 more
core +2 more sources
In a cardiac output (CO) sub-study of the Restrictive versus Liberal Fluid Therapy in Major Abdominal Surgery (RELIEF) trial, it was shown that restrictive fluid management was associated with lower cardiac index at the end of surgery.
Zachary Hollo+5 more
doaj +1 more source