Results 121 to 130 of about 211,431 (346)

Comparative Efficacy of Metabolic/Bariatric Surgery Versus GLP‐1 Receptor Agonists: A Network Meta‐Analysis of Randomized Controlled Trials

open access: yesObesity, EarlyView.
ABSTRACT Objective This study compared the efficacy of metabolic/bariatric surgery (MBS) and GLP‐1 receptor agonists (GLP‐1 RAs), including dual GLP‐1/GIP analogues, for weight and metabolic outcomes in adults with obesity. Methods A network meta‐analysis of randomized controlled trials compared MBS or GLP‐1 RAs versus lifestyle intervention in adults ...
Lucas Sabatella   +9 more
wiley   +1 more source

Weekly Subcutaneous VK2735, a GIP/GLP‐1 Receptor Dual Agonist, for Weight Management: Phase 2, Randomized, 13‐Week VENTURE Study

open access: yesObesity, EarlyView.
Four doses of VK2735 and a placebo group were included in the VENTURE study. Adults who were overweight or had obesity had significant weight loss when taking any dose of VK2735 for 13 weeks. More people lost at least 10% of their body weight as the dose increased.
Harold E. Bays   +9 more
wiley   +1 more source

Natural Compounds for the Treatment of Acute Pancreatitis: Novel Anti-Inflammatory Therapies

open access: yesBiomolecules
Acute pancreatitis remains a serious public health problem, and the burden of acute pancreatitis is increasing. With significant morbidity and serious complications, appropriate and effective therapies are critical.
Wenkai Jiang   +3 more
doaj   +1 more source

Efficacy and Safety of Tirzepatide in Japanese Participants With Obesity: A Subpopulation Analysis of the SURMOUNT‐1 Trial

open access: yesObesity, EarlyView.
ABSTRACT Objective This prespecified subpopulation analysis aimed to assess the efficacy and safety of once‐weekly tirzepatide versus placebo alongside lifestyle intervention in Japanese adults with obesity or overweight. Methods Data from 102 Japanese adults in the SURMOUNT‐1 trial with BMI ≥ 30 kg/m2 or ≥ 27 kg/m2 and ≥ 1 weight‐related comorbidity ...
Yasushi Ishigaki   +4 more
wiley   +1 more source

The Evolution of Pneumocystis jirovecii Pneumonia Prophylaxis for Pediatric Patients With Extracranial Solid Tumors: A Review of Historical Insights and Future Directions

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pneumocystis jirovecii pneumonia (PJP) remains a modern‐day complication for pediatric patients receiving treatment for extracranial solid tumors (ST), highlighting the need for reconsideration of our current approach toward PJP prophylaxis. This critical review aims to evaluate both universal and risk‐stratified approaches to PJP prophylaxis ...
Kriti Kumar   +8 more
wiley   +1 more source

Development and external validation of models to predict acute respiratory distress syndrome related to severe acute pancreatitis

open access: green, 2022
Yunlong Li   +7 more
openalex   +2 more sources

Machine Learning‐Based Risk‐Adjusted CUSUM Control Chart for Monitoring Readmission Rate Following PTBD Catheter Placement

open access: yesQuality and Reliability Engineering International, EarlyView.
ABSTRACT Percutaneous transhepatic biliary drainage (PTBD) catheter placement is known to have a high readmission rate. This work focuses on monitoring the change in readmission rate after a new clinical paradigm for post‐procedural care is implemented for the PTBD procedures.
Muhammed Aljifri   +2 more
wiley   +1 more source

Statistics, ethics, and probiotica

open access: yes, 2008
A randomized clinical trial comparing an experimental new treatment to a standard therapy for a life-threatening medical condition should be stopped early on ethical grounds, in either of the following scenarios: (1) it has become overwhelmingly clear ...
Gill, Richard D.
core   +5 more sources

Prognostic value of contrast‐enhanced ultrasound in dogs with acute renal injury treated with haemodialysis

open access: yesVeterinary Record, Volume 196, Issue 6, 15/22 March 2025.
Abstract Background It is clinically relevant to predict outcomes in dogs with acute kidney injury (AKI) treated with haemodialysis. The aim of this study was to evaluate the prognostic value of contrast‐enhanced ultrasound (CEUS) and its role in discriminating between AKI and acute impairment associated with chronic kidney disease (AKI/CKD).
Caterina Puccinelli   +3 more
wiley   +1 more source

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