Results 71 to 80 of about 1,680,433 (254)

MetaPaCS: A Novel Meta‐Learning Framework for Pancreatic Cancer Subtype Identification

Advanced Intelligent Systems, EarlyView.
We have developed MetaPaCS, an ensemble meta‐learning framework for reliable prediction of pancreatic cancer subtypes with high accuracy. MetaPaCS is capable of capturing subtype‐specific distinct gene expression patterns and drug‐disease associations for pancreatic cancer.
Nick B. Peterson, Mengtao Sun, Xinchao Wu, Jieqiong Wang, Shibiao Wan   +4 more
wiley   +1 more source

Diabetic Ketoacidosis-induced Hypertriglyceridemic Acute Pancreatitis Treated with Plasmapheresis—Recipe for Biochemical Disaster Management

, 2014
Diabetic ketoacidosis (DKA)-induced hypertriglyceridemia causing pancreatitis is an interesting phenomenon that has rarely been reported in literature. Plasmapharesis is a well known treatment modality for hypertriglyceridemia-induced pancreatitis.
Saurabh Rajpal, Moheb Boktor, Taru Saigal, James D. Morris, Abhishek Seth, Jonathan S. Alexander, Ankur Sheth, Kenneth Manas, Paul A. Jordan, John Bienvenu   +9 more
core   +1 more source

Pancreatic pseudocyst eroding into the splenoportal venous confluence and mimicking an arterial aneurysm [PDF]

, 2009
We report the case of a 62-year-old man with chronic pancreatitis who presented with increasing abdominal pain. Sonography, magnetic resonance imaging, contrast-enhanced computed tomography, and ultimately catheter angiography demonstrated a pancreatic ...
Lehnert, Thomas, Vogl, Thomas J. (Prof. Dr.), Nour-Eldin A. Nour-Eldin, Thomas J. Vogl, Naguib, Nagy Naguib Naeem, Koitka, Karen, Nagy N. Naguib, Alhajii, Waleed, Thomas Lehnert, Mohammed, Nour-Eldin Abdelrehim Nour-Eldin, Karen Koitka, Waleed Alhajii   +11 more
core   +1 more source

Safety outcomes of antidiabetic medications: A comprehensive review of the EU summaries of product characteristics and international clinical practice guidelines

British Journal of Clinical Pharmacology, EarlyView.
Aims Information on the safety profile of antidiabetic medications is essential for informed treatment decisions in type 2 diabetes mellitus. Although this information is available in regulatory documents of individual drugs, a comprehensive overview across all approved antidiabetics is lacking.
David Liang, Daniala L. Weir, Safana Thevasahayam, Vera H. M. Deneer, Arno Siebes, Helga Gardarsdottir   +5 more
wiley   +1 more source

Long‐acting cabotegravir and rilpivirine in people with HIV receiving chronic anticoagulation: A real‐world case series

British Journal of Clinical Pharmacology, EarlyView.
Background Long‐acting intramuscular cabotegravir plus rilpivirine (LA‐CAB + RPV) is an effective maintenance antiretroviral regimen for virologically suppressed people with HIV. However, its use in individuals receiving chronic anticoagulation is limited by concerns regarding intramuscular bleeding risk, and real‐world data are scarce.
Montserrat Laguno, Berta Torres, Maria Martínez‐Rebollar, Paula Arreba, Octavi Roman, Roger LLobet, Leire Berrocal, Alberto Foncillas, Júlia Calvo, Abiu Sempere, Ivan Chivite, Elisa de Lazzari, Josep Mallolas, Ana González‐Cordón   +13 more
wiley   +1 more source

Severe acute pancreatitis with abscess after extracorporeal shock wave lithotripsy: a rare complication

, 2017
Extracorporeal shock wave lithotripsy (ESWL) is a widely accepted procedure for urolithiasis. However, the shock waves do not pass through the body without damage.
Weng, Chu-Hao;Ho, Pei-Yin;Tsai, Chia-Chi;Hsu, Jong-Ming;Chen, Marcelo;Lin, Wun-Rong, 何蓓茵   +1 more
core   +1 more source

Acute Myeloid Leukemia Developing with Acute Pancreatitis Mimicking Autoimmune Pancreatitis [PDF]

, 2021
A 33-year-old man was admitted to our hospital for fever and abdominal pain. A blood analysis revealed pancytopenia and increased serum pancreatic enzymes with disseminated intravascular coagulation.
賀川, 久美子, Murai, Jumpei, 原田, 武志, Fujii, Shiroh, 323782/profile-ja.html, ムライ, ジュンペイ, カガワ, クミコ, スミタニ, リョウヘイ, 950, Oura, Masahiro, 安倍, 正博, 876, タカハシ, マミコ, 919, 60265/profile-ja.html, 10511321, ミキ, ヒロカズ, アベ, マサヒロ, ホリ, タイキ, オオウラ, マサヒロ, 528, 曽我部, 公子, 00618473, 1164, Harada, Takeshi, 450, 三木, 浩和, 1634, Abe, Masahiro, 80263812, 349366/profile-ja.html, Sumitani, Ryohei, 337582/profile-ja.html, ソガベ, キミコ, Takahashi, Mamiko, 藤井, 志朗, 246784/profile-ja.html, Kawata, Shiyori, 208060/profile-ja.html, カワタ, シヨリ, 中村, 信元, 大浦, 雅博, Sogabe, Kimiko, 580, Nakamura, Shingen, フジイ, シロウ, Hori, Taiki, 住谷, 龍平, Kagawa, Kumiko, 229265/profile-ja.html, ハラダ, タケシ, ナカムラ, シンゲン, Miki, Hirokazu, 50511333, 364652/profile-ja.html   +54 more
core  

Phase 1, open‐label, randomized study of the elecoglipron pharmacokinetic profile in healthy participants under fed and fasted conditions

British Journal of Clinical Pharmacology, EarlyView.
Aims Elecoglipron (AZD5004/ECC5004) is an oral small‐molecule glucagon‐like peptide‐1 receptor agonist (GLP‐1 RA) in development for weight management in people living with obesity or overweight and type 2 diabetes. This study aimed to characterize the pharmacokinetics (PK) profiles of two formulations of elecoglipron under fed and fasted conditions ...
Jianfeng Xu, Amina Haggag, Laurie Butcher, Haihui Liu, Wen Chen, Xuefeng Sun, Aruni Jha, Hongtao Yu, Anis Khan, Victoria E. R. Parker, Christer Tannergren, Xiaoliang Pan, Jianfeng Xu, Jingye Zhou   +13 more
wiley   +1 more source

Management of Acute Pancreatitis in Critical Care Unit

, 2010
Pancreatitis is characterized by an inflammation occuring due to digestion of pancreatic self tissues and other organs after activation of digestive enzymes which are stable under normal conditions . For all the pancreatitis cases, the mortality rate is
Güniz Meyancı Köksal
core   +1 more source

Safety and pharmacokinetics of inhaled aloxistatin: A first‐in‐human phase 1 dose escalation trial

British Journal of Clinical Pharmacology, EarlyView.
Aims Aloxistatin (E64d) is a membrane‐permeable cysteine protease inhibitor prodrug that is converted by esterases to the active metabolite E64c (loxistatin). This first‐in‐human study evaluated the safety, tolerability and pharmacokinetics of single ascending doses of inhaled E64d in healthy volunteers.
Sebastian Fähndrich, Franziska Friedrich, Daniel Soriano, Jona Gjeloshi, Björn C. Frye, Xuan Phuoc Nguyen, Lydia Herbstritt, Caroline von Spee‐Mayer, Britta Lang, Fabrice Nollevaux, Andreas Hoheisel, Dorothee Winterberg, Armin Braun, Thomas Epting, Christine Contini, Karl Winkler, Thomas Reinheckel, Franziska C. Trudzinski, Gernot Rohde, Daiana Stolz, Robert Bals, Martin J. Hug, Sebastian Wirtz, Christoph Peters, Carolin Jenkner   +24 more
wiley   +1 more source