Results 81 to 90 of about 2,864,300 (339)

PFKFB2‐Driven Glycolysis Promotes Dendritic Cell Maturation and Exacerbates Acute Lung Injury

Advanced Science, EarlyView.
Paraquat (PQ) or lipopolysaccharide (LPS) exposure activates the HIF‐1α–PFKFB2 pathway, driving glycolysis in dendritic cells (DCs). This metabolic shift enhances DC maturation and immune activation, exacerbating acute lung injury (ALI). This study demonstrates that PFKFB2‐driven glycolytic reprogramming in DCs plays a critical role in the pathogenesis
Ding Yuan, Fang Yang, Linlin Hou, Yan Zhang, Xin Pang, Yuqi Du, Hongyi Yan, Huanzhou Zhu, Yue Cheng, Yue Wu, Pinpin Jiang, Mengnan Guo, Mengying Zhang, Jinjie Guo, Huihui Hao, Yong Jiang, Yi Li, Yanxia Gao   +17 more
wiley   +1 more source

DIAGNOSTIC ACCURACY OF BEDSIDE INDEX OF SEVERITY IN ACUTE PANCREATITIS (BISAP) SCORE IN PREDICTING OUTCOMES IN PATIENTS PRESENTING WITH ACUTE PANCREATITIS

Pakistan Armed Forces Medical Journal, 2020
Objective: To determine the diagnostic accuracy of Bedside Index of Severity in Acute Pancreatitis score in predictting outcomes in terms of mortality and severe acute pancreatitis in patients presenting with acute pancreatitis.
Sarah Fatima, Waqas Ahmed, Khalid Ibrahim Akhtar, Muhammad Khalid Siddique, Rabia Mushtaq, Syed Muhammad Hashim Raza   +5 more
doaj   +2 more sources

Hypertriglyceridemia and acute pancreatitis: clinical and basic research—a narrative review

Journal of Pancreatology
Hypertriglyceridemia (HTG) is the third most common cause of acute pancreatitis (AP), and the incidence of HTG-induced AP (HTG-AP) is rising worldwide as a result of changes in lifestyle and dietary habits.
Lin Gao, Weiqin Li
doaj   +1 more source

The clinical characteristics of focal acute pancreatitis based on imaging diagnosis: comparison with non-localized acute pancreatitis- a preliminary result

BMC Gastroenterology, 2023
Background Focal acute pancreatitis is a special type of acute pancreatitis, which diagnosis is based on image showing a focal mass formation in the pancreas.
Mengmeng Ding, Renren Wang, Huawei Xu, Meng Li, Tao Zhou, Yueyue Li, Yanjing Gao, Xiaomeng Gu   +7 more
doaj   +1 more source

The use of complementary and alternative medicine is frequent in patients with pancreatic disorder [PDF]

, 2016
BACKGROUND: Herbal remedies and other complementary and alternative medicine (CAM) are used by 30% of the patients with liver and inflammatory bowel diseases.
Archibugi, L, Capurso, G., DELLE FAVE, Gianfranco, Stigliano, S, Zerboni, G   +4 more
core   +1 more source

Low-Grade Inflammation in the Association between Mild-to-Moderate Hypertriglyceridemia and Risk of Acute Pancreatitis: A Study of More Than 115000 Individuals from the General Population.

Clinical Chemistry, 2019
BACKGROUND How mild-to-moderate hypertriglyceridemia (2-10 mmol/L; 177-886 mg/dL) potentially causes acute pancreatitis is unknown; however, cellular studies indicate that inflammation might be a driver of disease progression.
Signe E. J. Hansen, C. M. Madsen, A. Varbo, B. Nordestgaard   +3 more
semanticscholar   +1 more source

An MOF‐Enhanced Anti‐Fouling Immunoprobe Platform for Efficient Direct Screening of Pancreatic Cancer

Advanced Science, EarlyView.
This work introduces an electrochemical sensing method that employs an innovative platform based on metal‐organic framework (MOF) for detecting biomarkers. The platform integrates an antifouling surface, oriented antibody immobilization, and an enhanced electron transfer layer.
Wenjuan Yang, Shujuan Mao, Hao Zhu, Handong Yao, Wei Jin, Lingyan Feng, Xinghua Gao, Xuefeng Wang, Wei Chen, Min Tu, Yuan Zhang   +10 more
wiley   +1 more source

Disseminated Nocardia cyriacigeorgia causing pancreatitis in a haploidentical stem cell transplant recipient. [PDF]

, 2017
We report the first published case of acute pancreatitis secondary to disseminated nocardiosis in a hematopoietic stem cell transplant (HSCT) recipient on chronic immunosuppression for graft-versus-host disease (GVHD).
Chen, MD, Jason, Filicko-O\u27Hara, Joanne, Flomenberg, Phyllis, Kasner, Margaret, Pan, MD, Jonathan   +4 more
core   +3 more sources

CXCR1 Depletion in Ly6C+ cDC2 Alleviates Acute Lung Injury via Modulation of Th17/Treg Balance

Advanced Science, EarlyView.
Pro‐inflammatory Ly6C⁺ cDC2s are identified as key effector cells mediating Cxcr1 signaling, driving the progression of ALI. Ly6C⁺ cDC2s release high levels of Il‐6 and Il‐1β, inducing Th17 differentiation. Cxcr1 deficiency reduces Il‐6 and Il‐1β production from Ly6C⁺ cDC2s through suppressing MEK1/ERK /NF‐κB signaling, thereby shifts naïve T cells ...
Shenghui Li, Wei Zhuang, Yang Wang, Hao Qin, Xichun Qin, Xianliang Yan, Xuefei Hu, Xiucheng Liu, Chang Chen   +8 more
wiley   +1 more source

Klebsiella predominance in peripancreatic microbial spectrum is associated with the severity of infected pancreatic necrosis

BMC Infectious Diseases
Background Infectious pancreatic necrosis (IPN) is associated with the prognosis of acute pancreatitis (AP). The correlation between microbial diversity in the peripancreatic region and AP severity remains unclear.
Xiaolan Guo, Yao Xu, Kaiwei Li, Jingzhu Zhang, Zhihui Tong, Weiqin Li, Donghuang Hong   +6 more
doaj   +1 more source