Results 31 to 40 of about 593,677 (304)

Mastitomics, the integrated omics of bovine milk in an experimental model of Streptococcus uberis mastitis: 1. High abundance proteins, acute phase proteins and peptidomics

open access: yesMolecular Biosystems, 2016
Acute phase proteins and a group of 77 peptides in a biomarker panel increase in milk during bovine mastitis caused by a Streptococcus uberis infection of mammary glands.
F. Thomas   +8 more
semanticscholar   +1 more source

Efficacy of bortezomib, cyclophosphamide and dexamethasone in treatment-naïve patients with high-risk cardiac AL amyloidosis (Mayo Clinic stage III)

open access: yesHaematologica, 2014
Bortezomib is an active agent in AL amyloidosis and responses to this drug in combination with cyclophosphamide and dexamethasone are both rapid and deep.
Arnaud Jaccard   +16 more
doaj   +1 more source

A novel mechano‐enzymatic cleavage mechanism underlies transthyretin amyloidogenesis

open access: yesEMBO Molecular Medicine, 2015
The mechanisms underlying transthyretin‐related amyloidosis in vivo remain unclear. The abundance of the 49–127 transthyretin fragment in ex vivo deposits suggests that a proteolytic cleavage has a crucial role in destabilizing the tetramer and releasing
Julien Marcoux   +17 more
doaj   +1 more source

Acute-phase proteins as diagnostic markers in horses with colic.

open access: yesJournal of Veterinary Emergency and Critical Care, 2016
OBJECTIVE To investigate the diagnostic potential of the concentrations of acute-phase proteins serum amyloid A (SAA), haptoglobin (Hp), and fibrinogen in blood and peritoneal fluid (PF) for differentiating horses with inflammatory colic (entero-colitis ...
T. H. Pihl   +8 more
semanticscholar   +1 more source

The Pentraxins 1975–2018: Serendipity, Diagnostics and Drugs

open access: yesFrontiers in Immunology, 2018
The phylogenetically ancient, pentraxin family of plasma proteins, comprises C-reactive protein (CRP) and serum amyloid P component (SAP) in humans and the homologous proteins in other species.
Mark. B. Pepys, Mark. B. Pepys
doaj   +1 more source

The diagnostic accuracy of acute phase proteins and proinflammatory cytokines in sheep with pneumonic pasteurellosis

open access: yesPeerJ, 2016
The goal of this study was to assess the diagnostic accuracy of acute phase proteins and proinflammatory cytokines in sheep with pneumonic pasteurellosis. Blood samples were collected from 56 sheep (36 naturally infected with Pasteurella multocida and 20
W. El-Deeb, A. Elmoslemany
semanticscholar   +1 more source

Multinucleated Giant Cells Are Specialized for Complement-Mediated Phagocytosis and Large Target Destruction

open access: yesCell Reports, 2015
Multinucleated giant cells (MGCs) form by fusion of macrophages and are presumed to contribute to the removal of debris from tissues. In a systematic in vitro analysis, we show that IL-4-induced MGCs phagocytosed large and complement-opsonized materials ...
Ronny Milde   +8 more
doaj   +1 more source

A Narrative Review of the Role of Transthyretin in Health and Disease

open access: yesNeurology and Therapy, 2020
Transthyretin (TTR) is a tetrameric transport protein highly conserved through vertebrate evolution and synthesized in the liver, choroid plexus, and retinal pigment epithelium. TTR transports the thyroid hormone thyroxine and the retinol-binding protein
Marcia Almeida Liz   +5 more
doaj   +1 more source

Acute phase response in lame crossbred dairy cattle [PDF]

open access: yesVeterinary World, 2016
Aim: The study was undertaken to study acute phase response based on acute phase proteins (APPs) such as C-reactive protein (CRP), haptoglobin (Hp), serum amyloid A (SAA), and fibrinogen in lame crossbred dairy cattle.
A. Bagga   +3 more
doaj   +1 more source

The major acute phase proteins of bovine milk in a commercial dairy herd

open access: yesBMC Veterinary Research, 2015
BackgroundMilk acute phase proteins (APP) have been identified and show promise as biomarkers of mastitis. However analysis of their profile in dairy cows from a production herd is necessary in order to confirm their benefits in mastitis diagnosis.
F. Thomas   +5 more
semanticscholar   +1 more source

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