Results 41 to 50 of about 7,955,704 (317)
A novel mechano‐enzymatic cleavage mechanism underlies transthyretin amyloidogenesis
EMBO Molecular Medicine, 2015 The mechanisms underlying transthyretin‐related amyloidosis in vivo remain unclear. The abundance of the 49–127 transthyretin fragment in ex vivo deposits suggests that a proteolytic cleavage has a crucial role in destabilizing the tetramer and releasing
Julien Marcoux +17 more
doaj +1 more source
The Pentraxins 1975–2018: Serendipity, Diagnostics and Drugs
Frontiers in Immunology, 2018 The phylogenetically ancient, pentraxin family of plasma proteins, comprises C-reactive protein (CRP) and serum amyloid P component (SAP) in humans and the homologous proteins in other species.
Mark. B. Pepys, Mark. B. Pepys
doaj +1 more source
Effect of short-term abomasal corn starch infusions on postruminal fermentation and blood measures
Journal of Dairy Science, 2023 : It is possible that some of the systemic responses to subacute ruminal acidosis (SARA) may be caused by increased intestinal starch fermentation. The objective of this experiment was to evaluate the effect of abomasal infusion of up to 3 g of corn ...
S.K. Cronin +5 more
doaj +1 more source
Cell Reports, 2015 Multinucleated giant cells (MGCs) form by fusion of macrophages and are presumed to contribute to the removal of debris from tissues. In a systematic in vitro analysis, we show that IL-4-induced MGCs phagocytosed large and complement-opsonized materials ...
Ronny Milde +8 more
doaj +1 more source
A Narrative Review of the Role of Transthyretin in Health and Disease
Neurology and Therapy, 2020 Transthyretin (TTR) is a tetrameric transport protein highly conserved through vertebrate evolution and synthesized in the liver, choroid plexus, and retinal pigment epithelium. TTR transports the thyroid hormone thyroxine and the retinol-binding protein
Marcia Almeida Liz +5 more
doaj +1 more source
The complementary role of histology and proteomics for diagnosis and typing of systemic amyloidosis
The Journal of Pathology: Clinical Research, 2019 The tissue diagnosis of amyloidosis and confirmation of fibril protein type, which are crucial for clinical management, have traditionally relied on Congo red (CR) staining followed by immunohistochemistry (IHC) using fibril protein specific antibodies ...
Tamer Rezk +12 more
doaj +1 more source
Acute phase response in lame crossbred dairy cattle [PDF]
Veterinary World, 2016 Aim: The study was undertaken to study acute phase response based on acute phase proteins (APPs) such as C-reactive protein (CRP), haptoglobin (Hp), serum amyloid A (SAA), and fibrinogen in lame crossbred dairy cattle.
A. Bagga +3 more
doaj +1 more source
The major acute phase proteins of bovine milk in a commercial dairy herd
BMC Veterinary Research, 2015 BackgroundMilk acute phase proteins (APP) have been identified and show promise as biomarkers of mastitis. However analysis of their profile in dairy cows from a production herd is necessary in order to confirm their benefits in mastitis diagnosis.
F. Thomas +5 more
semanticscholar +1 more source
The acute phase protein response to intramammary infection in water buffalo (Bubalus bubalis)
, 2010 Acute phase proteins are a group of serum proteins that change their concentration in animals following infection, inflammation or stress. Serum amyloid A (SAA) and α1-acid glycoprotein (AGP) are regarded as acute phase proteins in bovine, and their ...
P. Sartorelli +7 more
core +2 more sources
Blood fibrinogen concentrations in New Zealand White rabbits during the first year of life [PDF]
Bulgarian Journal of Veterinary Medicine, 2018 The aim of this study was to examine the reference range of blood plasma fibrinogen, which belongs to the group of moderate acute phase protein in rabbits. The experiment followed the dynamics of blood plasma fibrinogen (Fb) during the first year of life
Y. Petrova +3 more
doaj +1 more source