Results 141 to 150 of about 1,012,363 (342)

Hepatitis C virus core antigen assay: can we think beyond convention in resource limited settings?

Brazilian Journal of Infectious Diseases
Hepatitis C virus infects over 15 million patients from India and 2.86 million from Brazil. Detection of anti-hepatitis C virus antibodies has limited sensitivity during acute phase: the pre-seroconversion window period.
Anita Chakravarti, Mayank S. Chauhan, Gaurav Dogra, Sayantan Banerjee   +3 more
doaj   +1 more source

Relationship between gastro-intestinal complaints and endotoxaemia, cytokine release and the acute-phase reaction during and after a long-distance triathlon in highly trained men [PDF]

, 1999
A. E. Jeukendrup, K. Vet-Joop, Augueste Sturk, J. H. J. C. STEGEN, Joan M. Senden, W. H.M. Saris, Anton J. M. Wagenmakers   +6 more
openalex   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Luteinizing Hormone and Testosterone Levels during Acute Phase of Severe Traumatic Brain Injury: Prognostic Implications for Adult Male Patients

Frontiers in Endocrinology, 2018
Traumatic brain injury (TBI) is a worldwide core public health problem affecting mostly young male subjects. An alarming increase in incidence has turned TBI into a leading cause of morbidity and mortality in young adults as well as a tremendous resource
Alexandre Hohl, Alexandre Hohl, Fernando Areas Zanela, Gabriela Ghisi, Marcelo Fernando Ronsoni, Marcelo Fernando Ronsoni, Alexandre Paim Diaz, Alexandre Paim Diaz, Marcelo Liborio Schwarzbold, Marcelo Liborio Schwarzbold, Alcir Luiz Dafre, Alcir Luiz Dafre, Benjamin Reddi, Benjamin Reddi, Kátia Lin, Kátia Lin, Felipe Dal Pizzol, Felipe Dal Pizzol, Roger Walz, Roger Walz   +19 more
doaj   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Apparent diffusion in nucleus pulposus is associated with pain and mobility improvements after spinal mobilization for acute low back pain [PDF]

arXiv, 2017
Pain perception, trunk mobility in flexion, extension, and lateral flexion, and apparent diffusion coefficient (ADC) within nucleus pulposus of all lumbar discs were collected before and after posterior-to-anterior mobilization in 16 adults with acute low back pain.
arxiv  

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Relationship between gastro-intestinal complaints and endotoxaemia, cytokine release and the acute-phase reaction during and after a long-distance triathlon in highly trained men [PDF]

, 2000
Asker E. Jeukendrup, K. VET-JOOP, A. STURK, J.H.J.C. STEGEN, Joan M. Senden, W.H.M. SARIS, A.J.M. WAGENMAKERS   +6 more
openalex   +1 more source

CT Image Registration in Acute Stroke Monitoring [PDF]

arXiv, 2018
We present a new system based on tracking the temporal evolution of stroke lesions using an image registration technique on CT exams of the patient's brain. The system is able to compare past CT exams with the most recent one related to stroke event in order to evaluate past lesions which are not related to stroke.
arxiv