Results 31 to 40 of about 1,338,409 (341)

Optimization of the dosage regimen of zoledronic acid with a kinetic-pharmacodynamic model and exposure-response analysis

Frontiers in Pharmacology, 2023
Purpose: In order to support the dose optimization of zoledronic acid, the kinetic-pharmacodynamic model and exposure-response analysis were used to describe the changes in bone mineral density in different doses of zoledronic acid and establish the ...
Huan Wang, Huan Wang, Huan Wang, Qi Liu, Qi Liu, Muhan Jiang, Muhan Jiang, Chunli Song, Chunli Song, Dongyang Liu, Dongyang Liu   +10 more
doaj   +1 more source

Serum amyloid A primes microglia for ATP-dependent interleukin-1\u3b2 release [PDF]

, 2018
Acute-phase response is a systemic reaction to environmental/inflammatory insults and involves production of acute-phase proteins, including serum amyloid A (SAA).
A Basu, A Franceschini, AA Culbert, AJ Sharp, AL Giuliani, AM Van Dam, B Sperlágh, C Gabay, C Marinelli, C Solà, C Volonté, CA Dinarello, CM Uhlar, D Ferrari, D Kim, DL Thiele, E Gruys, E Nishida, E Venereau, G Guillemin, G Ristori, H Yokote, I Hardardóttir, I Kushner, I Rajkovic, J Saura, JA Sloane, JS Liang, JT Guo, K Chang, K Niemi, K Selmaj, L Facci, L Facci, L Peferoen, L Probert, L Sun, L Yao, Laura Facci, LK Parvathenani, M Barbierato, M Barbierato, M Casula, M Connolly, M De Buck, M Idzko, M Li, M Sanz, Massimo Barbierato, ME Hamby, MK McCoy, Morena Zusso, MS Kindy, MT Heneka, N Chauvet, N Cheng, P Honore, Pietro Giusti, R Ebert, RA Dal Canto, RJ Rodrigues, S Kim, S Sandri, S Tanaka, SD Skaper, SD Skaper, SD Skaper, SJ Crocker, SJ Hewett, SL Passey, SM Allan, Stephen D. Skaper, SY Seong, T Kawamoto, T Miida, T Tamamoto, TF Chung, TH Holm, XQ Li, Y Kumon, Y Wang, Y Yu, YR Ji   +82 more
core   +2 more sources

Differences in GlycA and lipoprotein particle parameters may help distinguish acute kawasaki disease from other febrile illnesses in children. [PDF]

, 2016
BackgroundGlycosylation patterns of serum proteins, such as α1-acid glycoprotein, are modified during an acute phase reaction. The response of acute Kawasaki disease (KD) patients to IVIG treatment has been linked to sialic acid levels on native IgG ...
Burns, Jane C, Connelly, Margery A, Kanegaye, John T, Otvos, James D, Pourfarzib, Ray, Shalaurova, Irina, Shimizu, Chisato, Tremoulet, Adriana H, Winegar, Deborah A   +8 more
core   +3 more sources

Prediction of musculoskeletal pain after the first intravenous zoledronic acid injection in patients with primary osteoporosis: development and evaluation of a new nomogram

BMC Musculoskeletal Disorders, 2023
Objective To construct a new prediction nomogram to predict the risk of musculoskeletal pain in patients with primary osteoporosis who receive zoledronic acid intravenously for the first time.
Xiaoxia Zheng, Jiangnan Ye, Qunzhang Zhan, Weifeng Zhao, Zhongqin Liao, Xiaolin Ye, Chongzheng Qu   +6 more
doaj   +1 more source

Plasmapheresis reduces cytokine and immune cell levels in COVID-19 patients with acute respiratory distress syndrome (ARDS)

Pulmonology, 2021
Background In December 2019, pneumonia associated with a novel coronavirus (COVID-19) was reported in Wuhan, China. Acute respiratory distress syndrome (ARDS) is the most frequently observed complication in COVID-19 patients with high mortality rates ...
Seyed MohammadReza Hashemian, Navid Shafigh, Golnaz Afzal, Hamidreza Jamaati, Payam Tabarsi, Majid Marjani, Majid Malekmohammad, Seyed Mehdi Mortazavi, Batoul Khoundabi, Davood Mansouri, Afshin Moniri, Abbas Hajifathali, Elham Roshandel, Esmaeil Mortaz, Ian M Adcock   +14 more
doaj   +3 more sources

Acute Phase Proteins in Marine Mammals: State of Art, Perspectives and Challenges

Frontiers in Immunology, 2019
The term “acute phase response” (APR) is referred to a nonspecific and complex reaction of an organism that occurs shortly after any tissue damage, such as infection, trauma, neoplasia, inflammation, and stress.
Maria Elena Gelain, Federico Bonsembiante, Federico Bonsembiante   +2 more
doaj   +1 more source

Acute extravascular hemolytic transfusion reaction due to anti-Kpa antibody missed by electronic crossmatch [PDF]

, 2014
BackgroundKpa antigen is a low incidence red blood cell antigen within the Kell system. Anti-Kpa alloantibody may be associated with acute and delayed hemolytic transfusion reactions.Case StudyWe report a case of a clinically significant acute ...
Berardi, Philip, Desjardins, Diana, Erickson, Kathy, Giulivi, Antonio, Neurath, Doris, Padmore, Ruth, Saidenberg, Elianna, Tokessy, Melanie   +7 more
core   +1 more source

Combined Inflammatory and Metabolic Defects Reflected by Reduced Serum Protein Levels in Patients with Buruli Ulcer Disease [PDF]

, 2014
Buruli ulcer is a skin disease caused by Mycobacterium ulcerans that is spreading in tropical countries, with major public health and economic implications in West Africa.
AA Pahlevan, AG Fraga, Arnaud Fontanet, B Meijer, BH Ji, C Demangel, Caroline Demangel, D Yeboah-Manu, DC Gore, E Coutanceau, E Coutanceau, E Peresi, EJ Park, F van de Goot, Fatoumata Niang, Fred S. Sarfo, FS Sarfo, FS Sarfo, FS Sarfo, FS Sarfo, Gerd Pluschke, H Hong, H Hong, J Guarner, J Trygg, JD Storey, Jordi Landier, K Asiedu, K Huygen, Kabiru Abass, KM George, L Guenin-Mace, L Guenin-Mace, M Wansbrough-Jones, Mark Forson, Mark Wansbrough-Jones, ME Posthauer, Michael Frimpong, PD Johnson, R Phillips, R Phillips, RE Simmonds, Reid Oldenburg, Richard O. Phillips, S Boulkroun, S Etuaful, WA Nienhuis, William Thompson, Y Benjamini   +48 more
core   +11 more sources

Effects of meeting the requirements in energy and protein, and of systemic inflammation on the interval from parturition to conception in dairy cows

Czech Journal of Animal Science, 2018
Main aim of this retrospective study was to determine the role of the level of meeting the requirements in net energy of lactation (NEL) and utilizable crude protein at the duodenum (uCP) in weeks 3-17 postpartum on the interval from parturition until ...
Elke Humer, Leonhard Gruber, Qendrim Zebeli   +2 more
doaj   +1 more source

Expression and Differential Responsiveness of Central Nervous System Glial Cell Populations to the Acute Phase Protein Serum Amyloid A [PDF]

, 2017
Acute-phase response is a systemic reaction to environmental/inflammatory insults and involves hepatic production of acute-phase proteins, including serum amyloid A (SAA). Extrahepatically, SAA immunoreactivity is found in axonal myelin sheaths of cortex
A Castellheim, A Ellis, AE Mullick, BK Lundholt, BM Schreiber, C Caltagirone, C Gabay, C Marinelli, C Nathan, C Nuccio De, C Rosin, C Solà, C Vaure, CM Uhlar, DB Noriega, DL Thiele, E Gruys, ES Wohleb, F Begum, F Caso, G Guillemin, GC Sellar, GS Getz, GW Duff, H Zheng, HJ Yu, I Hardardóttir, I Paterniti, I Paterniti, I Rajkovic, J Saura, JM Dopp, JS Liang, JT Guo, JW Jeong, J‐L Tchélingérian, K Selmaj, L Facci, L Probert, L Qin, L Sun, M Alhouayek, M Barbierato, M Bsibsi, M Buck De, M Cordaro, M Kopf, M Li, M Poljakovic, ME Hamby, MK McCoy, MS Kindy, N Castanon, N Cheng, N Marchi, P Matzinger, R Martini, RA Dal Canto, RL Meek, RM Ransohoff, S Amor, S Kim, S Lehnardt, S Sandri, S Spuler, SA Liddelow, SD Skaper, SD Skaper, SJ Crocker, SJ Hewett, SY Seong, T Kawamoto, T Miida, TC Theoharides, TF Chung, Y Kumon, Y Yu, YJ Jang   +77 more
core   +2 more sources