Results 51 to 60 of about 7,156,078 (242)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Development and evaluation of one step single tube multiplex RT-PCR for rapid detection and typing of dengue viruses

Virology Journal, 2008
Background Dengue is emerging as a major public health concern in many parts of the world. The development of a one-step, single tube, rapid, and multiplex reverse transcription polymerase chain reaction (M-RT-PCR) for simultaneous detection and typing ...
Parida Manmohan, Shrivastava Ambuj, Santhosh SR, Dash Paban, Saxena Parag, Rao PV   +5 more
doaj   +1 more source

Acute phase reaction to gadolinium-DTPA in dialysis patients [PDF]

Nephrology Dialysis Transplantation, 2008
Several late sequelae of the administration of gadolinium (Gd)-containing MRI contrast agents have been described in patients with advanced renal failure. In an observational series, we found a remarkable frequency of peracute reactions after administration of Gd-DTPA used for cardiovascular evaluation before renal transplantation.In a 26-month ...
Henning, Steen, Evangelos, Giannitsis, Claudia, Sommerer, Udo, Bahner, Margit, Brandl, Christoph, Merbach, Constanze, Merten, Eberhard, Ritz, Hugo A, Katus, Martin, Zeier, Vedat, Schwenger   +10 more
openaire   +2 more sources

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Potential of acute phase proteins as predictor of postpartum uterine infections during transition period and its regulatory mechanism in dairy cattle [PDF]

Veterinary World, 2016
Among the various systemic reactions against infection or injury, the acute phase response is the cascade of reaction and mostly coordinated by cytokines-mediated acute phase proteins (APPs) production.
A. Manimaran , A. Kumaresan , S. Jeyakumar , T. K. Mohanty , V. Sejian , Narender Kumar , L. Sreela , M. Arul Prakash , P. Mooventhan , A. Anantharaj , D. N. Das   +10 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Association of Cardiovascular Complications with Acute Phase Response in Kawasaki Patients

پزشکی بالینی ابن سینا, 2002
Investigation of risk factors leading to cardiac complications in    Kawasaki disease is extremely important because coronary vasculitis may    lead to aneurysmal formation , stenosis and myocardial infarction.
Abdollah A. Karimi, Alireza Nateghian, Mehran Karimi, Behzad Shirvani   +3 more
doaj  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Long-term self-reported health and disability after COVID-19 in public employees

BMC Public Health, 2022
Background Although the symptomatology has been assessed in multiple studies among persons recovering from coronavirus disease 2019 (COVID-19), less is known regarding long-term general health and disability.
Linda Ashman Kröönström, Johanna Krause, Simon B. Larsson, Robert Sigström, Katharina Stibrant Sunnerhagen   +4 more
doaj   +1 more source

Optimization of the indications for allogeneic stem cell transplantation in Acute Myeloid Leukemia based on interactive diagnostic strategies [PDF]

, 2011
The indications for allogeneic stem cell transplantation (SCT) in Acute Myeloid Leukemia (AML) represent a real challenge due to the clinical and genetic heterogeneity of the disorder.
Hartwig, Maite, Zander, Axel R., Haferlach, Torsten, Fehse, Boris, Bacher, Ulrike, Kröger, Nicolaus   +5 more
core   +1 more source